Free shipping on all orders over $ 500

Featured Products


Cat.No.  Name Information
M1817 Y-27632 dihydrochloride Y-27632 is a potent, selective inhibitor of Rho-associated protein kinases (ROCK) with IC50 values of 140-220 nM for ROCK1 and ROCK2.
M1925 LY294002 LY294002 is a highly selective PI3K inhibitor with IC50 values of 0.31, 0.73, 1.06 and 6.60 μM for PI3Kβ, PI3Kα, PI3Kδ and PI3Kγ respectively.
M1837 MK-2206 2HCl MK-2206 is a novel allosteric inhibitor of Akt with IC50 values of 8 nM, 12 nM and 65 nM for Akt1, Akt2 and Akt3, respectively.
M1715 GDC-0941 GDC-0941 is a selective and potent inhibitor of Class I PI3K, p110a IC50=0.003uM, U87MG IC50=0.95μM.
M1902 MG132 MG132 is a specific and potent cell-permeable proteasome inhibitor (IC50 = 100 nM, Ki = 4 nM).
M4005 PDTC PDTC is a selective nuclear factor-κB (NF-κB) inhibitor.
M4839 Cell Counting Kit-8 Cell Counting Kit-8 (CCK-8) allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays.
M1988 Dabrafenib Dabrafenib (free base) (GSK2118436A) is a V600 mutant BRAF-specific inhibitor.
M1820 Tofacitinib Tofacitinib (formerly tasocitinib, CP-690550) is a novel Janus Kinase 3 (JAK-3) kinase inhibitor with an IC50 value estimated at 0.2 μM.
M2082 Streptozotocin Streptozotocin is a small molecule antibiotic and a potent DNA methylating agent.
M1977 U0126 U0126 is a potent and highly selective non-competitive inhibitor of MAPK/ERK kinase with IC50 of 72 nM for MEK1 and 58 nM for MEK2.
M1861 CX-4945 CX-4945 (Silmitasertib) is a potent small molecule protein kinase inhibitor that selectively binds to and inhibits the enzyme casein kinase II (CK2).
M1759 GSK1120212 (Trametinib) GSK1120212 (JTP-74057) is a highly potent and selective MEK inhibitor with IC50 values to be 0.7 and 0.9 nM for MEK1 and MEK2 respectively and with long circulating half-life.
M1671 BEZ235 BEZ235 (NVP-BEZ235) is a potent dual PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively.
M1768 Rapamycin Rapamycin (Sirolimus,Rapamune)is an inhibitor of mTOR.The mammalian target of rapamycin (mTOR) is a kinase responsible for mitogen-induced cell proliferation/survival signaling.
M1732 BMN673 BMN673 is a potent inhibitor of poly (ADP-ribose) polymerases (PARP)-1 and -2.
M1763 PD-0325901 PD-0325901 is a highly potent and selective MEK inhibitor with an IC50 in C26 cells of 0.33nM.
M1746 DAPT DAPT (GSI-IX) is a γ-secretase inhibitor with IC50 values of 115 and 200 nM for total Aβ and Aβ42 respectively.
M1646 AG490 AG490 (Tyrphostin AG490) is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively).
M1738 Niltubacin Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.
M2080 INCB28060 INCB28060 is a novel inhibitor of c-MET kinase with IC50 of 0.13 nM.
M2223 Cisplatin Cisplatin is a potent anticancer agent that blocks DNA synthesis.
M3722 Temsirolimus Temsirolimus (CCI-779) is a specific mTOR inhibitor with IC50 of 1.76 μM.
M4879 Cycloheximide Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, with IC50 of 532.5 nM.
M1637 ABT-263 ABT-263 (Navitoclax) is a potent, orally bioavailable inhibitor of the antiapoptotic Bcl-2 family members Bcl-2, Bcl-x (L), and Bcl-w.
M2129 Temozolomide (TMZ) Temozolomide (TMZ) is an oral DNA methylating, chemotherapeutic agent.
M2048 Sumatriptan succinate Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.
M1966 Fulvestrant Fulvestrant (Faslodex) is a novel estrogen receptor (ER) antagonist (IC50 = 0.29 nM).
M3115 VE-822 VE-822 is an ATR inhibitor with IC50 of 19 nM.
M1737 MF63 MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme respectively.
M2296 3-Methyladenine (3-MA) 3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM, respectively.
M1749 Gefitinib Gefitinib (ZD-1839, Iressa) is a novel potent EGFR tyrosine kinase inhibitor with an IC50 of 0.40nM.
M1666 AZD8055 AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase (both complexes mTORC1 and mTORC2) with an IC50 of 0.8 nM.
M2017 ABT-199 ABT-199 is a highly potent, orally bioavailable and BCL-2 inhibitor.
M2302 PF-562271 PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.
M2562 ZCL278 ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM.
M2084 SCH772984 SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
M2288 Carboplatin Carboplatin is a DNA synthesis inhibitor by binding to DNA and interfering with the cell's repair mechanism.
M2143 MK-1775 MK-1775 is a potent and selective small molecule Wee1 kinase inhibitor with IC50 of 5.2 nM.
M2112 LY2835219 LY2835219 is an orally available inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM, respectively.
M1712 FTY720 FTY720 (Fingolimod) is a sphingosine-1-phosphate receptor 1 receptor.
M1970 Paclitaxel Paclitaxel is a mitotic inhibitor with IC50 of 0.1 pM in human endothelial cells.
M2066 Staurosporine Staurosporine (AM-2282) is a potent ATP-competitive kinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively.
M2076 SP600125 SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M1664 AZD2281 (Olaparib) AZD 2281 (Olaparib, KU-0059436) is a potent PARP (poly ADP-ribose polymerase) inhibitorwith IC50 of 5 and 1 nM for PARP-1and PARP-2 respectively.
M7528 Phosphatase Inhibitor Cocktail (EDTA-Free) AbMole Phosphatase Inhibitor Cocktail (EDTA-Free) is a mixture of protease inhibitors prepared by 8 independent protease inhibitors according to the optimized ratio. It is divided into A and B two tubes: A tube is a phosphate - root analogue to prevent the loss of phosphorylation of proteins and lipids , and B tube is a new natural product to provide more comprehensive protection for phosphatase.
M2053 Wortmannin Wortmannin is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM.
M1781 SB203580 SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3-5 μM.
M1802 Lapatinib Ditosylate Lapatinib Ditosylate (CAS 388082-78-8) is a selective and effective inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM) and ErbB-4 kinase (Ki = 347 nM).
M4748 Pectolinarigenin Pectolinarigenin is a dual inhibitor of COX-2/5-LOX with anti-inflammatory activity.
M1680 BKM120 BKM120 (NVP-BKM120) is a potent and highly specific oral pan-class I PI3K inhibitor.
M1661 AZD6244 AZD6244 (ARRY-142886, Selumetinib) is a potent MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nM.
M3030 S-Ruxolitinib S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
M2108 SB-525334 SB-525334 is a potent activin receptor-like kinase (ALK5)/ type I TGFβ-receptor kinase inhibitor with IC50 of 14.3 nM.
M2167 (+)-JQ1 (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.
M1686 Bortezomib Bortezomib (Velcade) is a highly selective proteasome inhibitor with a ki value of 6nM.


Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.