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Featured Products

Hot and exclusive products from AbMole during 2014!
Cat.No.  Name Information
M5169 EAI045 EAI045 is an allosteric inhibitor that targets selected drug-resistant EGFR mutants but spares the wild-type receptor.
M2346 Filgotinib Filgotinib (GLPG0634) is the first selective inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively.
M2302 PF-562271 PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 with IC50 of 1.5 nM and 14 nM, respectively.
M2189 MLN4924 MLN4924 is a novel small molecule NAE inhibitor with IC50 of 4 nM.
M2185 Nutlin-3 Nutlin-3 is a selective MDM2 (mouse double minute 2) antagonist with IC50 of 90 nM.
M2104 BYL719 BYL719 is the first oral PI3K inhibitor that strongly and selectively inhibits the PI3K alpha isoform of PI3K.
M2084 SCH772984 SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
M2017 ABT-199 ABT-199 is a highly potent, orally bioavailable and BCL-2 inhibitor.
M2008 ICG-001 ICG-001 is a novel small molecule inhibitor of TCF/beta-catenin-mediated transcription.
M1966 Fulvestrant Fulvestrant (Faslodex) is a novel estrogen receptor (ER) antagonist (IC50 = 0.29 nM).
M1934 FK-506 FK-506 is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin.
M1902 MG132 MG132 is a specific and potent cell-permeable proteasome inhibitor (IC50 = 100 nM, Ki = 4 nM).
M1861 CX-4945 CX-4945 (Silmitasertib) is a potent small molecule protein kinase inhibitor that selectively binds to and inhibits the enzyme casein kinase II (CK2).
M1768 Rapamycin Rapamycin (Sirolimus,Rapamune)is an inhibitor of mTOR.The mammalian target of rapamycin (mTOR) is a kinase responsible for mitogen-induced cell proliferation/survival signaling.
M1759 GSK1120212 GSK1120212 (JTP-74057) is a highly potent and selective MEK inhibitor with IC50 values to be 0.7 and 0.9 nM for MEK1 and MEK2 respectively and with long circulating half-life.
M1753 Trichostatin A Trichostatin A (TSA) is a potent, reversible inhibitor of mammalian histone deacetylase (HDAC) with IC50 value around 20 nM.
M1750 TAK-733 TAK-733 is a potent and selective MEK allosteric site inhibitor with IC50 of 3.2nM for the treatment of cancer.
M1742 Tubacin Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.
M1734 BAY-60-7550 BAY-60-7550 is a potent PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human).
M1732 BMN673 BMN673 is a potent inhibitor of poly (ADP-ribose) polymerases (PARP)-1 and -2.

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