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Chloroquine diphosphate

Cat. No. M2510

All AbMole products are for research use only, cannot be used for human consumption.

Chloroquine diphosphate Structure
Synonym:

Chloroquine Phosphate

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
50mg USD 30  USD30 In stock
100mg USD 50  USD50 In stock
200mg USD 75  USD75 In stock
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Quality Control & Documentation
Biological Activity

Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent.

Product Citations
Customer Product Validations & Biological Datas
Source International Journal of Neurosci (2020 Mar) Figure 7. chloroquine (Abmole Bioscience Inc., Houston, TX, USA)
Method Apoptosis detection
Cell Lines BM-MNCs
Concentrations 0 μM, 2.0 μM, 4.0 μM, 8.0 μM or 16.0 μM
Incubation Time 48 h
Results The cell viabilities (means ± SD) of the five 3-MA-treated groups was 100%, 73.13 ± 3.02%, 56.45 ± 2.70%, 34.35 ± 1.65% and 10.14 ± 0.93%, respectively (Figure 7a), while those of the five CHQ-treated groups were 100%, 65.99 ± 3.26%, 48.79 ± 2.51%, 28.04 ± 2.54% and 3.02 ± 0.70%, respectively (Figure 7b).
Chemical Information
Molecular Weight 515.86
Formula C18H26ClN3.2H3O4P
CAS Number 50-63-5
Solubility (25°C) Water ≥ 30 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Xiaoguang Hao, et al. Chloroquine diphosphate suppresses liver cancer via inducing apoptosis in Wistar rats using interventional therapy

[2] Yan-Jie Han, et al. Advances and challenges in the prevention and treatment of COVID-19

[3] Mayla Gabriela Silva Borba, et al. Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial

[4] Jianjun Gao, et al. Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

[5] Thandar Aye, et al. Utility of chloroquine diphosphate in the blood bank laboratory

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Keywords: Chloroquine diphosphate, Chloroquine Phosphate supplier, Autophagy, inhibitors, activators

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