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Cytokines Cytokines

Inhibitors

Cat.No.  Name Information
M9370 Recombinant Human TNF α(HEK293) Recombinant Human TNF α(HEK293)
M9413 Recombinant Human VEGF165(HEK293) Recombinant Human VEGF165(HEK293) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M11533 DKK-1 (Mammalian,N-8His) Recombinant Human Dickkopf-related protein 1 is produced by our Mammalian expression system and the target gene encoding Thr32-His266 is expressed with a 8His tag at the N-terminus.
M11496 FGF-basic, Rat(E. coli) FGF-basic, Rat(E. coli) Expressed with an n-terminal Gly. FGF-basic (Pro10-Ser154) Accession # P13109. Bioactivity: ED50 < 0.25 ng/ mL, measured by 3T3 cell proliferation method, corresponding to > 4.0 × 106 units /mg.
M11495 TNF-α, Human (E. coli) TNF-α, Human (E. coli) Protein structure: TNF-α (VAL77-LEU233) Accession # P01375. Bioactivity: ED50 < 30.0 pg/ mL, measured in cytotoxicity assay of L-929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D, corresponding specific activity > 3.3 × 107 units /mg.
M11494 BMP-2, Human(E. coli) BMP-2, Human(E. coli) Protein structure: BMP-2 (GLN283-ARG396) Accession # P12643. Biological activity: Experiment 1: To determine its ability to induce alkaline phosphatase production in ATDC-5 cells. The ED50 for this effect is generally 0.07-0.2µg/ mL. Experiment 2: The ability of inducing ALKALINE phosphatase production in C2C12 cells was determined. The ED50 for this effect is usually 0.2-1µg/ mL.
M11493 SCF, Human (P. pastoris) SCF, Human (P. pastoris) The protein was Expressed with an n-terminal Met. SCF (Glu26-Ala189) Accession # P21583-1. Biological activity: ED50 was < 2.0 ng/ mL by dose-dependent tF-1 cell stimulation, corresponding specific activity was 5 × 105IU /mg.
M11492 Endostatin, Human (P. pastoris) Endostatin, Human (P. pastoris) Protein structure: Endostatin (AlA1571-Lys1754) Accession # P39060. Biological activity: determined by endothelial tubule formation. Endostatin concentration of 10 μg/ mL showed obvious anti-angiogenesis effect.
M11491 IL-33, Mouse(E. coli) IL-33, Mouse(E. coli) Protein structure: IL-33 (SER109-ILE266) Accession # Q8BVZ5. Bioactivity: Fully bioactive compared to the standard. The ED50 measured by D10S cell proliferation assay was less than 0.5 ng/ mL, corresponding to a specific activity of > 2.0 × 106IU /mg.
M11490 VEGF165, Human(P. pastoris) VEGF165, Human(P. pastoris) Protein structure: VEGF165 (ALA27-ARG191) Accession # P15692-4. Biological activity: ED50 was 1.0-5.0 ng/ mL, which stimulated HUVEC cell proliferation in a dose-dependent manner, corresponding specific activity was 2.0 × 105-1.0 × 106 units /mg.
M11489 MCP-1/CCL2, Human(E. coli) MCP-1/CCL2, Human(E. coli) Protein structure: McP-1 (GLN24-THR99) Accession # P13500. Bioactivity: EC50 value of Human McP-1 /CCL2 against Cho-K1 /Gα15/hCCR2(human Gα15 and human CCR2 are stably expressed in Cho-K1 cells)Ca2+ mobilization assay was less than 1.0 μ G/mL.
M11488 Recombinant Human PDGF-BB(E. coli) Protein structure: PDGF-BB (SER82-THR190) Accession # P01127 Bioactivity: The ED50 of this effect was less than 10 ng/ mL in BALB/ C 3T3 cell proliferation assay
M11487 Recombinant Mouse M-CSF Protein(E. coli) Expressed with an n-terminal Met. M-CSF (Lys33-Pro187) Accession # P07141 Biological activity; ED50 < 3.0 ng/ mL, measured in mouse M-NFS-60 cell proliferation assay, corresponding to > 3.3 × 105 units /mg.
M11486 Recombinant Mouse M-CSF Protein(CHO) Protein structure: M-CSF (Lys33-PRO187) Accession # P07141 Bioactivity: ED50 < 3.0 ng/ mL, measured in mouse M-NFS-60 cell proliferation assay, corresponding to > 3.3 × 105 units /mg.
M11485 Recombinant Mouse GM-CSF Protein(E. coli) Expression system: E. coli Bioactivity: ED50 < 5.0 pg/ mL, measured in cell proliferation assay of mouse FDC-P1 cells, corresponding specific activity > 2.0 × 108 units /mg.
M11480 Bmp-7 protein, Human (E. coli) The BMP-7 protein, Human (E. coli), is a potent bone morphogenetic protein and part of the transforming growth factor (TGF-β) superfamily.
M11471 Recombinant Human CCL5 protein(E.coli) Protein construction: The DNA sequence encoding human CCL5 (SER24-SER91) was fused with the GST marker Biological activity: Chemokines for blood monocytes, memory T helper cells and eosinophils. Cause basophils to release histamine and activate eosinophils.
M11464 Recombinant Human RANKL (E.coli) Recombinant Human RANKL is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK).
M11391 Recombinant Human 4-1BB Ligand Protein (HEK293) Recombinant Human 4-1BB Ligand Protein (HEK293) Protein sequence: DNA sequence encoding human 4-1BB Ligand (NP_003802.1) expressed with Fc tag at c-terminal Bioactivity: Fixed human 4-1BB (His tag) at a concentration of 1ug/mL (100 μL/ well) can bind 4-1BB ligands (Fc tag) in a linear range of 1.25-20ug/mL
M11390 Recombinant Human 4-1BB Protein (HEK293) Recombinant Human 4-1BB Protein (HEK293) Protein sequence: DNA sequence encoding human 4-1BB (UniProtKB/ Swiss-PROt: Q07011.1) expressed with His tag at the C-terminal Bioactivity: 4-1BB, also known as CD137, is a member of the tumor necrosis factor receptor superfamily 9 (TNFRSF9) induced by lymphocyte activation (ILA), and is a costimulatory molecule of the tumor necrosis factor receptor superfamily.
M11389 Anti-human CD3/CD28 beads for T cell Bioactivity: CD3/CD28 mab conjugated magnetic beads are mainly used for isolation, activation and in vitro amplification of human T cells.
M11388 Anti-human CD137 mAb Biological activity: CD137(also known as 4-1BB) is an inducible cell surface receptor, a member of the tumornecrosis factor receptor (TNFR) superfamily.



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