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Abmole Inhibitor Catalog 2017

Cytokines Cytokines

Inhibitors

Cat.No.  Name Information
M10669 Recombinant Human/Murine/Rat Activin A (CHO) Activin A is a homodimer of two βA chains that is involved in tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin A protects the heart from hypoxic stress and promotes the differentiation of embryonic stem cells into cardiomyocytes.
M10638 Recombinant Human Interleukin-31 (E. coli) Human Interleukin-33 (IL-33) is a proinflammatory cytokine that belongs to the IL-1 family. IL-33 plays a role in autoimmune disease. IL-33’s interaction with ST2 can drive allergic pathology and IL-33 has been reported to play a role in the development of rheumatoid arthritis and systemic lupus erythematosus.
M10610 Recombinant Human Fibroblast Growth Factor 9 (E. coli) Fibroblast growth factor-9 (FGF-9) is a steroid-regulated mitogen and survival factor for nerve and mesenchymal cells.
M10603 Anti-human CD28 mAb CD28 molecule exists on the surface of most T cells and is considered to be a specific surface molecule of T cells. The responsiveness of T cells to antigens is mainly mediated by the CD3/TCR complex, but it also depends on the cooperation of other molecules on the surface of T cells.
M10601 SCF, Mouse (P. pastoris) Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). It stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
M10592 Recombinant Human M-CSF (CHO-expressed) Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages.
M10558 Recombinant human VEGF-C (HEK 293) Recombinant human VEGF-C (rhVEGF-C) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels.
M10536 Recombinant Human Interleukin-31 (E. coli) Recombinant Human Interleukin-31 (IL-31) signals through IL-31 receptor A and oncostatin M receptor subunits and can activate STAT3 through receptors and maybe involve in skin immunity.
M10512 Recombinant Human Interleukin-6 (E. coli) Recombinant Human IL-6 is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine.
M10466 Recombinant Mouse Interleukin-4 (IL-4) (E. coli) Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression.
M10465 Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression.
M10460 Recombinant Rat Insulin-like Growth Factor-1 (E. coli) Recombinant Rat Insulin-like Growth Factor-1 belonged to the insulin gene family, it is mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro.
M10430 Recombinant Human TGF-α (E. coli) Recombinant Human TGF-α, also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells.
M10354 Recombinant Human EGF (E. coli) Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells.
M10353 Recombinant Human FGF-10/KGF-2 (E. coli) Recombinant Human Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in the lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF and receptor binding to FGFR2-IIIb.
M10352 Recombinant Human HGF (CHO-expressed) Recombinant human Hepatocyte Growth Factor (rhHGF) , also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells.
M10344 Recombinant Human Glial Cell Line-derived Neurotrophic Factor Glial cell-derived neurotrophic factor is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
M10313 Recombinant Human Granulocyte Colony Stimulating Factor (CHO-expressed) Human Granulocyte Colony Stimulating Factor (G-CSF) is a pleiotropic cytokine, mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ.
M10297 Recombinant Rat Interferon-gamma (CHO-expressed) Recombinant Rat Interferon-gamma (IFN-γ, Rat) also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells.
M10296 Recombinant Murine Interleukin-2 IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.
M10286 Recombinant Murine Midkine Midkine is a heparin-binding growth factor, which contains 121 amino acid residues with 5 disulfide bonds.
M10115 Recombinant Murine TNFα Protein TNF-α is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts.
M10111 Anti-human CD3 mAb CD3 is an important marker of T cells, it is composed of five polypeptide chains: γ, δ, ε, ζ, and η.
M10022 Recombinant Murine GM-CSF Protein Recombinant Murine GM-CSF Protein is a hematopoietic growth factor that can promote the development of neutrophils and macrophages, and promote the proliferation and development of early erythroid megakaryocytes and eosinophilic progenitors.
M10021 Recombinant Murine BMP-4 Protein Recombinant Murine BMP-4 Protein is a TGF-beta superfamily ligand that is widely expressed from early embryogenesis through adulthood.
M10020 Recombinant Murine TPO Protein Recombinant Murine TPO Protein is a lineage-specific growth factor produced in the liver, kidney, and skeletal muscle, stimulates the proliferation and maturation of megakaryocytes and promotes the increase of platelet circulation in the body.
M10019 Recombinant Rat M-CSF Protein Recombinant Rat M-CSF Protein is a powerful hematopoietic factor produced by lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.
M10018 Recombinant Rat IL-4 Protein Recombinant Rat IL-4 Protein is a multidirectional cytokine that regulates various T cell and B cell responses such as cell proliferation, survival, and gene expression.
M10017 Recombinant Rat TNFα Protein Recombinant Rat TNFα Protein is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts.
M10016 Recombinant Rat EGF Protein Recombinant Rat EGF Protein is type Itransmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc.
M10015 Recombinant Murine IL-6 Protein Recombinant Murine IL-6 Protein is produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, and has a variety of biological functions.
M10014 Recombinant Murine M-CSF Protein Recombinant Murine M-CSF Protein is a powerful hematopoietic factor produced by lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.
M10013 Recombinant Murine VEGF165 Protein Recombinant Murine VEGF165 Protein is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M10012 Recombinant Human IFN-ω Protein Recombinant Human IFN-ω Protein signals through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities.
M10011 Recombinant Human IFN-α 2b Protein Human IFN-α2a and -α2b are allelic variants of the same gene, the IFN-α subtype is classified as an intermediate/strong ISG inducer and has strong antiviral activity against influenza A virus.
M10010 Recombinant Human Fetuin A Protein Recombinant Human Fetuin A Protein is a major plasma protein and a member of the cystatin superfamily of protease inhibitors.
M10009 Recombinant Human Apo-transferrin Protein Transferrin is iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids.
M10007 Recombinant Human Holo-Transferrin Protein Transferrin is iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids.
M10006 Recombinant Human rHSA Protein Recombinant Human rHSA Protein is a single-chain aglycosylated protein consisting of 585 amino acid residues, has many important physiological properties and has a wide range of uses.
M10005 Recombinant Human CXCL1 Protein Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family.
M10004 Recombinant Human KGF(FGF-7) Protein Recombinant Human KGF(FGF-7) Protein is a mitogenic factor specific to epithelial cells and keratinocytes, it plays an important role in the development of kidney and lung, as well as angiogenesis and wound healing.
M10003 Recombinant Human FGF-8b Protein Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect.
M10002 Recombinant Human sTRAIL/Apo2L Protein Recombinant Human sTRAIL/Apo2L Protein is a cytotoxic protein that can activate the rapid apoptosis of tumor cells, but does not work in normal cells.
M10001 Recombinant Human Rantes(CCL5) Protein Recombinant Human Rantes(CCL5) Protein is a CC chemokine that can signal through CCR 1, CCR 3, CCR 5 and US 28 (cytomegalovirus receptor).
M10000 Recombinant Human Vitronectin Protein Recombinant Human Vitronectin Protein is a secreted glycoprotein synthesized in the liver. It mainly circulates in the form of monomers, but can undergo conformational changes to form disulfide bond-connected multimers.
M9999 Recombinant Human Noggin Protein Recombinant Human Noggin Protein can bind to ligands of the transforming growth factor-β family and regulate its activity by inhibiting its pathway with signal receptors.
M9998 Recombinant Human LIF Protein Recombinant Human LIF Protein promotes the long-term maintenance of embryonic stem cells by inhibiting the spontaneous differentiation of embryonic stem cells.
M9997 Recombinant Human IFN-λ1 Protein Recombinant Human IFN-λ1 Protein uses an independent receptor system consisting of IFN-λR1 subunit (also called CRF 2-12) and IL-10R2 subunit (also called CRF 2-14) to induce an antiviral defense similar to type I interferon, but different from type I interferon.
M9996 Recombinant Human Vimentin Protein Recombinant Human Vimentin Protein is a type III intermediate filament protein, which mainly exists in cells of mesenchymal origin, such as vascular endothelial cells and blood cells, and is the main component of the cytoskeleton.
M9994 Recombinant Human IGF-1 LR3 Protein Recombinant Human IGF-1 LR3 Protein is a mitogenic polypeptide growth factor that can stimulate the proliferation and survival of various cells, including muscle, bone and cartilage tissue.


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