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Cat.No.  Name Information
M9601 Cariprazine Cariprazine is a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor.
M9600 2-Aminoethyl diphenylborinate (2-APB) 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release.
M9599 NB-598 NB-598 is a potent competitive inhibitor of squalene epoxidase (SE).
M9598 Evans Blue Evans blue is a biological dye, for detection of cell survival. Evans Blue can not penetrate healthy cell membrane, but can penetrate into death cell.
M9597 Vonafexor Vonafexor is a farnesoid X receptor agonist.
M9596 Pemigatinib Pemigatinib (INCB054828) is an orally bioavailable inhibitor of FGFR with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively.
M9595 Upamostat Upamostat is an orally bioavailable, second generation serine protease inhibitor targeting the human urokinase plasminogen activator (uPA) system with potential antineoplastic and antimetastatic activities.
M9594 EDC.HCl Crosslinker EDC.HCl Crosslinker is a zero-length crosslinker that can be used to conjugate carboxyl functional groups to primary amines.
M9593 Iminodiacetic acid Iminodiacetic acid is a bovine liver glutamate dehydrogenase inhibitor.
M9592 Theaflavin 3,3'-digallate Theaflavin 3,3'-digallate (TF3) is an antitumor agent.
M9591 D-(+)-Trehalose dihydrate D-(+)-Trehalose dihydrate is used as a food ingredient and pharmaceutical excipient.
M9590 Acotiamide dihydrochloride Acotiamide is a potent, selective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE).
M9589 Rifamycin sodium Rifamycin sodium belongs to the family of ansamycin antibiotics, it is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase.
M9588 SNAP SNAP is a nitrosothiol derivative, releases nitric oxide, acts as a stable inhibitor of platelet aggregation.
M9587 NDI-091143 NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay).
M9586 ZT-12-037-01 ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor with IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N), respectively.
M9585 MAC-545496 MAC-545496 is potent GraR inhibitor (glycopeptide-resistance-associated protein R), reverses β-lactam resistance in the community-acquired MRSA USA300 strain.
M9584 SAM-315 SAM-31 (WAY-255315) is selective 5-Hydroxytryptamine-6 antagonists.
M9583 Dansylsarcosine piperidinium salt Dansylsarcosine piperidinium salt
M9582 Tris Dodecyl Sulfate Tris Dodecyl Sulfate
M9581 AZD1390 AZD1390 is a potent and selective inhibitor of ATM in cells (IC50 = 0.78 nM) with the ability to cross the blood-brain barrier.
M9580 β-Nicotinamide mononucleotide β-nicotinamide mononucleotide (β-NM) is an intermediate in NAD+ biosynthesis produced from nicotinamide (NAM) and phosphoribosyl pyrophosphate (PRPP) by nicotinamide phosphoribosyl transferase enzyme with no toxicity.
M9579 XMD-17-51 XMD-17-51 is a potent and selective NUAK1 inhibitor.
M9578 BI-2852 BI-2852 is a potent KRAS inhibitor that binds with nanomolar affinity to a pocket.
M9577 RA190 hydrochloride RA190 HCl is a potent RPN13 and ADRM1 Inhibitor, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
M9575 NVP-DPP-728 dihydrochloride NVP-DPP-728 dihydrochloride is a potent and selective dipeptidyl peptidase IV inhibitor.
M9574 Ginkgetin Ginkgetin is a natural biflavonoid isolated from leaves of Ginkgo biloba L. with effects of anti-inflammation and anticancer activity.
M9573 Orexin A (human, mouse, rat, bovine) Orexin A (human, mouse, rat, bovine) is a specific, high-affinity agonist for G-protein-coupled receptor OX1R.
M9572 α-Melanocyte stimulating hormone α-Melanocyte-stimulating hormone (α-MSH) is a tridecapeptide, mostly produced by the cells in the brain, pituitary and circulation.
M9571 Pin1 inhibitor API-1 Pin1 inhibitor API-1 is a Pin1 inhibitor with an IC50 of 72.3 nM.
M9570 PTP1B-IN-9 PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor with anticancer activity.
M9569 AB928 AB928 is an orally bioavailable, dual antagonist of the A2aR and A2bR adenosine receptors, leads to greater immunomodulatory activity and reduced tumor growth.
M9568 SC-26196 SC-26196 is a potent, orally active D6D inhibitor (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA).
M9567 Leptin (116-130) mouse Leptin (116-130) mouse is a synthetic leptin peptide fragment.
M9566 Glycine Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
M9565 RU 24969 hemisuccinate RU 24969 hemisuccinate is a selective agonist at the 5-HT1A and 5-HT1B receptors.
M9564 Lumiflavine Lumiflavine is a structural analog of the water-soluble vitamin riboflavin.
M9563 2,1,3-Benzothiadiazole-5-carbaldehyde 2,1,3-Benzothiadiazole-5-carbaldehyde
M9562 Huperzine A Huperzine A is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor extracted from traditional Chinese herb.
M9561 A-485 A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.
M9560 Paquinimod Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
M9559 Chloroquine Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis, it is also a autophagy and toll-like receptors (TLRs) inhibitor.
M9558 JSH-150 JSH-150 is a potent CDK9 inhibitor with IC50 of 1 nM.
M9557 BAY-1816032 BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM.
M9556 Potassium thiocyanate Potassium thiocyanate is an inorganic potassium salt. Potassium thiocyanate (KSCN) may be used for the colorimetric quantification of intracellular iron content of the superparamagnetic iron oxide (SPIO) nanoparticles.
M9555 Endothelin-1 (human, porcine) Endothelin-1 (human, porcine) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.
M9554 BQ-123 BQ-123 is a selective endothelin A receptors (ETAR) antagonist with an IC50 value of 7.3 nM.
M9553 PF-06873600 PF-06873600 is an orally bioavailable, cyclin-dependent kinase (CDK) inhibitor, with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.
M9552 Stigmasterol Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
M9551 Coixol Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen.
M9550 Sivelestat Sivelestat (ONO5046; LY544349; EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM.
M9549 Nonaethylene glycol monododecyl ether Nonaethylene glycol monododecyl ether is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification.
M9548 CZC-8004 CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.
M9547 VTX-27 VTX-27 is a novel potent and selective PKCθ inhibitor, with Kis of 0.08 nM and 16 nM for PKC θ and PKC δ.
M9546 TBK1/IKKε-IN-5 TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively.
M9545 Hydrocortisone Hemisuccinate Hydrocortisone hemisuccinate is an anti-inflammatory agent.
M9544 Heparan Sulfate Heparan sulfate is a complex and linear polysaccharide, which expressed abundantly on the cell surface and in the extracellular matrix.
M9543 Dextran Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation.
M9542 TMRM Perchlorate TMRM Perchlorate is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).
M9541 DM4 DM4, a chemical derivative of maytansine, is a potent and selective cytotoxic agent that inhibit cell division.
M9540 ODM-203 ODM-203 is an orally available inhibitor of VEGFR and FGFR, with IC50s of 26, 9, 5 nM for VEGFR1, VEGFR2 and VEGFR3, and 11, 16, 6, 35 nM for recombinant FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
M9539 Dansylcadaverine Dansylcadaverine is a fluorescent probe.
M9538 Nisin Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species.
M9537 Protein kinase inhibitors 1 Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
M9536 VBIT-12 VBIT-12 is a potent inhibitor of VDAC1, directly interacting with purified VDAC1 and reducing its channel conductance.
M9535 Mobocertinib Mobocertinib (TAK-788) is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions.
M9534 TAS6417 TAS6417 is a novel EGFR inhibitor targeting exon 20 insertion mutations, with IC50 values range from 1.1-8.0 nM.
M9533 DS-1001b DS-1001b is a potent mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor with antitumor activity.
M9532 BO-264 BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM.
M9531 NADP disodium salt NADP disodium salt is a participant coenzyme in aerobic and anaerobic oxidations.
M9530 Inarigivir soproxil Inarigivir soproxil, also known as SB 9200, is a novel agonist of innate immunity, which shows potent antiviral activity against resistant HCV variants.
M9529 L-Glutamic acid monosodium salt hydrate L-Glutamic acid monosodium salt hydrate is also a Kainate receptor, NMDA receptor and quisqualate receptor agonist; an excitatory amino acid neurotransmitter.
M9528 KPT-9274 KPT-9274, also known as PAK4-IN-1, is a potent, selective and dual PAK4/NAMPT inhibitor with IC50s of less than 100 and 120 nM, respectively.
M9527 BMVC-8C3O BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s.
M9526 GSK-J5 GSK-J5 is a cell-permeable, inactive control for histone demethylase JMJD3/UTX inhibitor GSK-J4.
M9525 Pamiparib Pamiparib (BGB-290) is an orally active, potent, highly selective inhibitor of PARP1 and PARP2 with IC50 values of 0.9 nM and 0.5 nM, respectively.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria.
M9523 PEG6000 PEG6000 is a neutral and biocompatible hydrophilic polymer.
M9522 SRI-011381 SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
M9521 Glumetinib Glumetinib, also known as SCC244, is a novel, potent and highly selective inhibitor of c-Met with an IC50 of 0.42 nM.
M9520 BCECF-AM BCECF-AM is a cell membrane permeable compound, widely used as a fluorescent indicator for intracellular pH.
M9519 Nelonicline Nelonicline (ABT-126) is a nicotinic acetylcholine receptor agonist.
M9518 BN82002 BN82002, also known as CDC25 Phosphatase Inhibitor I, is a potent, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively).
M9517 Sodium hippurate Hippuric acid is a low molecular weight phenolic carboxylic acid urinary metabolite that may be a useful urinary biomarker for certain cancers such as gastric cancer and oxidative stress.
M9516 INF39 INF39 is a nontoxic, irreversible NLRP3 inhibitor able to decrease interleukin-1β release from macrophages.
M9515 MS417 MS417 (also known as GTPL7512) is a potent and selective BRD4 inhibitor, which binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30 and 46 nM, respectively.
M9514 JDTic JDTic is a kappa opioid receptor (KOR) antagonist that prevents stress-induced reinstatement of cocaine-maintained responding and has antidepressant-like effects.
M9513 BTdCPU BTdCPU is an potent activator of HRI, it promotes eIF2α phosphorylation and induced apoptosis in resistant cell.
M9512 PLX5622 PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM.
M9511 DO264 DO264 is a potent selective, and in vivo active ABHD12 inhibitor, with an IC50 of 11 nM.
M9510 JWG-071 JWG-071 is the first reported kinase-selective chemical probe for ERK5, inhibits ERK5 and LRRK2 with IC50 of 88 and 109 nM, respectively.
M9509 NS-3-008 hydrochloride NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM.
M9508 C75 trans C75 trans is an enantiomer of C75, which is a synthetic fatty-acid synthase (FASN) inhibitor.
M9507 ML-109 ML-109 is a full agonist of TSHR (thyroid stimulating hormone receptor) with an EC50 of 40 nM.
M9506 TH5487 TH5487 is a selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC50 of 342 nM.
M9505 Compound E Compound E is a cell-permeable, potent, selective inhibitor of γ-secretase and Notch processing.
M9504 D-Desthiobiotin D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation.
M9503 E1210 E1210 (APX001A) is the first-in-class inhibitor of the fungal protein Gwt1 (GPI-anchored wall transfer protein 1) in the glycosylphosphatidylinositol (GPI) biosynthesis pathway.
M9502 CVT-12012 CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively.
M9501 AN2718 AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS.


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