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Cat.No.  Name Information
M6145 BMS-5 BMS-5 is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively).Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
M6144 BMS-3 BMS-3 is a potent inhibitor of LIMK1.LIM kinase 1 (LIMK1) activity is essential for cell migration and cell cycle progression.
M6143 SP2509 SP2509 is a selective histone demethylase LSD1 inhibitor with IC50 of 13 nM, showing no activity against MAO-A, MAO-B, lactate dehydrogenase and glucose oxidase.
M6142 XY1 XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.
M6141 NIBR189 NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).
M6140 TA 01 TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively).
M6139 GSK2256098 GSK2256098 is a potent, selective, reversible, and ATP competitive FAK kinase inhibitor with apparent Ki of 0.4 nM.
M6138 E-7046 E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities.
M6137 PF-05175157 PF-05175157 (Compound 9) is a potent Acetyl-CoA carboxylase (ACC1) inhibitor with IC50s of 23.5±1.1 nM (rat) and 27.0±2.7 nM (human).
M6136 Epacadostat Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
M6135 Calicheamicins The calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable.
M6134 Tildipirosin Tildipirosin is a derivative of the naturally occurring compound tylosin.
M6133 Oritavancin diphosphate Oritavancin is approved for the treatment of adult patients with acute bacterial skin and skin structure infections (SSSIs) caused by or suspected to be caused by susceptible isolates of designated gram-positive microorganisms.
M6132 ECBN HCL ECBN obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-d-glucan synthase.
M6131 Pristinamycin The pristinamycins exhibit a strong synergistic antibacterial activity against a wide range of Gram-positive and some Gram-negative bacteria, including methicillin- and vancomycin-resistant strains.
M6130 Zotarolimus Zotarolimus (ABT-578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.
M6129 Dalfopristin Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-drug resistant Enterococcus faecium infections.
M6128 BOC-D-FMK Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 µM.
M6127 TD-4208 TD-4208 is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity.
M6126 Triazolo-pyramidine derivative Triazolo-pyramidine derivative is a purine receptor antagonist.
M6125 AKP-11 AKP-11 has potent immune modulatory activity for treatment of EAE/MS, but with relatively low adverse effects suggesting AKP-11 as a potential therapeutic drug for MS patients.
M6124 Lubiprostone Lubiprostone is an orally active prostone that locally and selectively activates ClC-2 chloride channels to enhance the intestinal fluid secretion without altering the serum electrolyte levels.
M6123 Nandrolone phenylpropionate Nandrolone phenylpropionate (NPP) is an anabolic-androgenic steroid. The low androgenicity and enhanced anabolic activity of NPP has shown to positively influence calcium metabolism and to increase bone mass in osteoporosis.
M6122 ChlordehydroMethyl Testosterone Testosterone is normally present in the circulation of both men and women. Due to the dynamic regulation of endogenous testosterone production, including the acute effects of competition and exercise, testosterone concentrations may vary considerably within and among individuals.
M6121 Testosterone phenylpropionate Testosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester.
M6120 Testosterone isocaproate Testosterone Isocaproate help in increasing the body weight and will also help in gaining the strength and also help in losing fat in the body and gives an increase in libido, red blood cells, stamina and quick recovery after heavy training.
M6119 Testosterone Enanthate Androcur-treatment abolished testosterone-reduced cAMP, coupled with a changed expressional milieu of cAMP signaling elements. Results from in vitro experiments suggest that some of these effects are testosterone-AR dependent, while others could be due to disturbed LH and/or other signals.
M6118 666-15 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM.
M6117 Testosterone decanoate As with all forms of testosterone,Testosterone Decanoate will cause weight and strength gain, fat loss, a libido increase, an increase in IGF-1 levels, Red Blood Cell count, and of course increased recovery from training
M6116 Drostanolone Enanthate Drostanolone is one of the most frequently detected anabolic androgenic steroids in doping control analysis.
M6115 Drostanolone Propionate Drostanolone propionate can reduce the uptake of oestradiol-17B by tumour cells
M6114 Metandienone Metandienone is a synthetic anabolic steroid that is prohibited in sports by the World Anti-Doping Agency (WADA).
M6113 Hastatoside Hastatoside is isolated from Verbena species and exhibits various biological activities including sleep-promoting.
M6112 Thiamine chloride Thiamine chloride —the biologically active form of vitamin B1—is vital for all cellular life because it is a co-factor for several essential enzymes.
M6111 Meta-Fexofenadine Fexofenadine is a nonsedating antihistamine drug which is indicated for treatment of seasonal allergic rhinitis.
M6110 Levomefolic acid Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
M6109 Calcium N5-methyltetrahydrofolate Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.
M6108 Levomefolate calcium Levomefolate is an artificial form of folate.
M6107 Trenbolone Trenbolone(β-Trenbolone) is a steroid used by veterinarians on livestock to increase muscle growth and appetite.
M6106 17α-Methyltestosterone 17α-Methyltestosterone has similar binding affinity to AR and similar androgenic and anabolic activities as testosterone. IC50 value: 17 nM (Ki) Target:Androgen Receptor.
M6105 Testosterone Testosterone is an androgen, which binds the androgen receptor.
M6104 Ipilimumab Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 kD.
M6103 Cetuximab Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation. MW : 145.781 KD.
M6102 Pembrolizumab Pembrolizumab is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. MW : 146.286 KD.
M6101 Atezolizumab Atezolizumab is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of PD-L2 with PD-1. MW : 145 KD.
M6100 Nivolumab Nivolumab is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1,PCD-1) with immune checkpoint inhibitory and antineoplastic activities. MW : 143.597 KD.
M6099 Boldenone Undecylenate Boldenone undecylenate(Equipoise) is a synthetic steroid which has a similar effect as the natural steroid testosterone.
M6098 Baicalein Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM.
M6097 Corynoxine Corynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
M6096 JQ-1 carboxylic acid (+)-JQ1 carboxylic acid is the carboxylic acid form of (+)-JQ1 for derivative synthesis.
M6095 FGF-401 FGF-401 is an inhibitor of FGFR4 extracted from patent WO2015059668A1, compound example 83; has an IC50 of 1.9 nM.
M6094 Darunavir Darunavir is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.
M6093 SQ22536 SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.
M6092 Mirogabalin Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS.
M6091 Cadazolid Cadazolid, a novel fluoroquinolone-oxazolidinone antibiotic, exhibits potent in vitro activity against Clostridium difficile, including the epidemic BI/NAP1/027 strain.
M6090 Cilastatin Cilastatin is a dehydropeptidase I inhibitor that acts on the brush border membrane of the proximal tubule to prevent accumulation of imipenem and toxicity.
M6089 XMD8-92 XMD8-92 is a potent and selective BMK1/ERK5 inhibitor with Kd of 80 nM.
M6088 LY2409881 LY2409881 is a novel selective inhibitor of IKK2 with IC50 of 30 nM; IC50 for IKK1 and other common kinases is at least one log higher.
M6087 LXR-623 LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.
M6086 SBI-0206965 SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 .
M6085 GSK-1014802 CNV1014802(GSK-1014802) is a novel small molecule state-dependent sodium channel blocker; Nav1.7 sodium channel inhibitor.
M6084 IPI549 IPI549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM.
M6083 AZD9496 AZD9496 is an oral estrogen receptor inhibitor that blocks the growth of ER-positive and ESR1 mutant breast tumours in preclinical models.
M6082 2,6-Dichloro-3,5-dimethoxyaniline 2,6-Dichloro-3,5-dimethoxyaniline is H3B-6275 intermediate.
M6081 EAI045 EAI045 is an allosteric inhibitor that targets selected drug-resistant EGFR mutants but spares the wild-type receptor.
M6080 BAY-1895344 Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models
M6079 Triiodothyronine Triiodothyronine is a potent agonist of both thyroid hormone receptors TRα and Trβ with Kis of 2.3 nM for both.
M6078 CFI-402257 CFI-402257 is a highly selective and orally bioavailable TTK and Mps1 inhibitor with Kis of 0.1 and 0.09 nM, respectively.
M6077 LTURM34 LTURM34 is a specific DNA-PK inhibitor, 170-fold more selective for DNA-PK activity compared to PI3K activity, with IC50 value of 0.034 μM.
M6076 Miquelianin Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid.
M6075 HA15 HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
M6074 AA26-9 AA26-9 is a potent and broad spectrum serine hydrolase inhibitor.
M6073 WT161 WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM.
M6072 Iberdomide Iberdomide (CC-220) is a cereblon modulator in clinical development for systemic lupus erythematosis. Iberdomide exhibits an IC50 of 60 nM in TR-FRET cereblon binding assay.
M6071 Lu AF21934 Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4.
M6070 EDO-S101 EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively.
M6069 β-Estradiol 17-acetate β-Estradiol 17-acetate is a metabolite of estradiol.
M6068 Zonisamide Zonisamide is a voltage-dependent sodium channel and T-type calcium channel blocker, used as an antiepileptic drug.
M6067 Zomepirac sodium salt Zomepirac Sodium is a pyrrole-acetic acid structurally related to tolmetin sodium; a prostaglandin synthetase inhibitor.
M6066 Zolpidem Zolpidem is a benzodiazepine agonist with high selectivity for α1-subunit-containing GABAA receptors.
M6065 Ziprasidone HCl monohydrate Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity.
M6064 Ziprasidone HCl Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder.
M6063 Zatebradine Zatebradine(UL-FS49) is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner; 92% inhibition of the hHCN1-mediated current at 10 uM.
M6062 Xylose Xylose is a sugar first isolated from wood.
M6061 Xylometazoline HCl Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.
M6060 Xylazine HCl Xylazine is an α2-Adrenergic receptor agonist, used as a sedative and muscle relaxant.
M6059 Warfarin Warfarin is one of the most widely used anticoagulant drugs worldwide, used in the prevention of thrombosis and thromboembolism, the formation of blood clots in the blood vessels and their migration elsewhere in the body.
M6058 Vortioxetine Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
M6057 Vitamin E Vitamin E is a fat-soluble vitamin with potent antioxidant properties. It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.
M6056 Vitamin D2 Vitamin D2 is a selective inhibitor of mammalian DNA polymerase A (pol A) with IC50 of 123 mM.
M6055 Vitamin B12 Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
M6054 Vinpocetine Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease.
M6053 Vidarabine Vidarabine is an antiviral drug by interfering with the synthesis of viral DNA, used to treat herpes simplex and varicella zoster viruses.
M6052 Vernakalant HCl Vernakalant Hcl(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
M6051 Venlafaxine Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.
M6050 Venlafaxine HCl Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
M6049 Vecuronium Bromide Vecuronium is a non-depolarizing neuromuscular blocking agent, used for skeletal muscle relaxation during surgery.
M6048 Vardenafil HCl Vardenafil Hcl is a PDE5 inhibitor used for treating erectile dysfunction.
M6047 Ursodiol Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 μM)
M6046 Uridine Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.


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