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Cat.No.  Name Information
M9153 ACY-738 ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50s of 1.7 nM.
M9152 CPI-637 CPI-637 is a potent and selective CBP/EP300 bromodomains inhibitor with IC50 of 0.03±0.01μM and 11.0±0.6 μM for CBP/EP300 and BRD4, respectively.
M9151 MI-503 MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM.
M9150 MI-463 MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the Menin-MLL interaction, with an IC50 value of 15.3 nM.
M9149 MI-136 MI-136 inhibits DHT-induced expression of androgen receptor (AR) target genes.
M9148 SRT2104 SRT2104 is a selective brain-permeable activator of SIRT1.
M9147 Peficitinib Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.
M9146 GSK1324726A GSK1324726A (I-BET726) is a highly selective inhibitor of BET family proteins with IC50 of 41 nM, 31 nM, and 22 nM for BRD2, BRD3, and BRD4, respectively.
M9145 MI-2 MI-2 (Menin-MLL Inhibitor 2) is a potent menin-MLL interaction inhibitor with IC50 of 446±28 nM.
M9144 PFI-3 PFI-3 is a selective chemical probe for SMARCA bromodomains, including SMARCA2, SMARCA4 and PB1(5) bromodomains with a Kd of 89 nM.
M9143 HPOB HPOB is a highly potent and selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 56 nM, >30 fold less potent against other HDACs.
M9142 FLLL32 FLLL32 is a potent JAK2/STAT3 inhibitor with IC50 of <5 μM.
M9141 SGC-CBP30 SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively.
M9140 Hinokitiol Hinokitiol (β-thujaplicin) is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
M9139 Benzamide Benzamide is an inhibitor of poly(ADP-ribose) polymerase with an IC50 of 3.3 μM.
M9138 Picolinamide Picolinamide is a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
M9137 Elamipretide Elamipretide, also known as MTP-131, is a cardiolipin peroxidase inhibitor and mitochondria-targeted peptide.
M9135 TAK-779 TAK-779 is a potent and selective nonpeptide antagonist of CCR5, with a Ki of 1.1 nM for CCR5.
M9134 Citreoviridin Citreoviridin is a mycotoxin and potent inhibitor of mitochondrial ATPase.
M9133 AKBA AKBA is an active triterpenoid compound from the extract of Boswellia serrata and Boswellia carteri Birdw, exerts anti-inflammatory therapeutic effects and noncompetitively inhibits 5-lipoxygenase, topoisomerase, and leukocyte elastase.
M9132 ABM-3627 ABM-3627, also known as Mutant EGFR inhibitor, is a selective and potent Mutated EGFR inhibitor.
M9131 ZK-756326 dihydrochloride ZK-756326 dihydrochloride is a potent, selective and non-peptide CCR8 chemokine receptor agonist.
M9130 LSN3154567 LSN3154567 (also known as Nampt-IN-1) is a potent and elective NAMPT inhibitor, inhibits purified NAMPT with an IC50 of 3.1 nM.
M9129 GNE-131 GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.
M9128 AZ31 AZ31 is a potent and highly selective ATM inhibitor.
M9127 ONO-8590580 ONO-8590580 is a GABAAα5 negative allosteric modulator which enhances long-term potentiation and improves cognitive deficits in preclinical models.
M9126 Ac-CoA Synthase Inhibitor 1 Ac-CoA Synthase Inhibitor 1 (also known as ACSS2 Inhibitor), an anti-virus agent, is a Ac-CoA Synthase Inhibitor.
M9125 Z-Guggulsterone Z-Guggulsterone is a mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM).
M9124 DY268 DY268 is a potent FXR antagonist with IC50 of 7.5 nM.
M9123 MBX-4132 MBX-4132 is a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.
M9122 Tormentic Acid Tormentic Acid is a natural anti-inflammatory agent which inhibits production of tumor necrosis factor‑α (TNF‑α), interleukin 6 (IL‑6), and IL‑1β.
M9121 LY303511 hydrochloride LY303511 hydrochloride is a structural analogue of LY294002. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors.
M9120 Hexacosanoic acid Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
M9119 JNJ-632 JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D.
M9118 Chebulinic acid Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity.
M9117 W-54011 W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist, which inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM.
M9116 Atorvastatin Atorvastatin is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.
M9115 PF-06869206 PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with an IC50 of 380 nM.
M9114 LAU159 LAU159 is a potent, functionally selective α6β3γ2 GABAA receptor modulator.
M9113 Bictegravir Bictegravir (GS-9883) is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
M9112 AB-423 AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells.
M9111 Nidufexor Nidufexor is a farnesoid X receptor (FXR) agonist.
M9110 Alanosine Alanosine, also known as L-alanosine, is an amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
M9109 Corn oil Corn oil, extracted from the germ of corn, can be used as a carrier for drug molecules and has anti-tumor activity.
M9108 AZD-0364 AZD-0364 is a potent and selective ERK2 inhibitor with an IC50 of 0.6 nM.
M9107 LOXO-195 LOXO-195 is a potent and selective, next-generation TRK inhibitor, with IC50 values of 0.6±0.1 nM, <2.5 nM for TRKA and TRKC, respectively.
M9106 ST-193 ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
M9105 ARV-771 ARV-771 is a small-molecule pan-BET degrader with Kd values of 4.7, 7.6, 7.6 nM against BRD2, BRD3 and BRD4, respectively.
M9104 HX 531 HX 531 is a potent antagonist of retinoid X receptors (IC50 = 18 nM).
M9103 Eleclazine hydrochloride Eleclazine HCl is a novel late Na+ current inhibitor, with IC50 value of 0.7 uM.
M9102 Palosuran Palosuran, also known as ACT-058362, is a Urotensin-II receptor antagonist with an IC50 of 3.6±0.2 nM.
M9101 Exatecan mesylate Exatecan Mesylate is a water soluble topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL).
M9100 PLX51107 PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively.
M9099 SCH23390 SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively).
M9098 HDAC8-IN-1 HDAC8-IN-1 is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.
M9097 GLPG1837 GLPG1837 (ABBV-974) is a novel CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
M9096 H2DCFDA H2DCFDA is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS).
M9095 Marinopyrrole A Marinopyrrole A (Maritoclax) is a novel and specific Mcl-1 inhibitor with an IC50 value of 10.1 μM.
M9094 EG00229 Trifluoroacetate salt EG00229 Trifluoroacetate is the first small molecule inhibitor of the neuropilin-1 and VEGF-A interaction with an IC50 of inhibition of 8 uM (125I-VEGF binding to PAE/NRP1 cells).
M9093 DTT Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent; as a reducing or "deprotecting" agent for thiolated DNA.
M9092 Hemin chloride Hemin is an iron-containing porphyrinis potentially for the treatment of gastroparesis.
M9091 A-779 A-779 is a specific antagonist of G-protein coupled receptor (Mas receptor).
M9090 Tranylcypromine hemisulfate Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO).
M9089 SAR7334 SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.
M9088 SRI-011381 hydrochloride SRI-011381 hydrochloride is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
M9087 FICZ FICZ is a potent aryl hydrogen receptor (AhR) agonist.
M9086 NAD+ NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
M9085 Indoximod Indoximod, also known as NLG8189 and D-1MT is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor with a Ki value of 19 μM.
M9084 STING-Inducer-1 STING-Inducer-1 (ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes).
M9083 Disitertide Disitertide is a TGF-β1 inhibitor.
M9082 ISO-1 ISO-1, also known as MIF Antagonist, is a MIF inhibitor with an IC50 of 7 uM.
M9081 Sodium Stibogluconate Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase.
M9080 Substance P Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
M9079 Angiotensin-(1-7) Angiotensin (1-7) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7), inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM.
M9077 MDK-6314 MDK-6314 (STAT5-IN-1) is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain, with an IC50 of 47 μM for STAT5β isoform.
M9076 NADPH tetrasodium salt NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes.
M9075 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt.
M9074 GSK872 GSK872 is a receptor interacting protein kinase-3 (RIP3) inhibitor, which inhibits kinase activity with an IC50 of 1.3 nM.
M9073 Apatinib Apatinib is a selective VEGFR2 inhibitor with IC50 of 1 nM.
M9072 ATP Adenosine triphosphate (ATP) is an adenine nucleotide containing three phosphate groups esterified to the sugar moiety.
M9071 Amyloid beta-peptide(25-35) Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.
M9070 AMG 487 AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8.2nM for I-IP-10 and I-ITAC, respectively.
M9069 AS1842856 AS1842856 is a cell-permeable Foxo1 inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM.
M9068 Mitoquinone mesylate Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant.
M9067 TG-100572 hydrochloride TG-100572 hydrochloride is a potent and selective multi-targeted VEGFR2/Src kinase inhibitor.
M9066 PT2385 PT2385 is an orally active, selective inhibitor of hypoxia inducible factor (HIF)-2alpha, with a Ki value of less than 50 nM.
M9065 Ac-DEVD-CHO Ac-DEVD-CHO is a specific inhibitor of Caspase-3 with a Ki value of 230 pM.
M9064 Oxytocin acetate Oxytocin acetate is a mammalian neurohypophysial hormone.
M9063 TLR2-IN-C29 TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling.
M9062 Necrosulfonamide Necrosulfonamide is an MLKL inhibitor with IC50 value of 124 nM in human HT-29.
M9061 Dehydroepiandrosterone Dehydroepiandrosterone is an effective antiapoptotic factor.
M9060 RSL3 RSL3 is an inhibitor of the glutathione (GSH) peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system.
M9059 TBHQ TBHQ is an aromatic organic compound, as a selective inducer of Nrf2 in a preclinical model of ICH.
M9058 Varenicline hydrochloride Varenicline hydrochloride is a nicotinic receptor partial agonist.
M9057 XMU-MP-1 XMU-MP-1 is a potent and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively.
M9056 Losartan Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
M9055 INT-777 INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM.
M9054 Valproic acid Valproic acid is an HDAC inhibitor with IC50 in the range of 0.5~2 mM.
M9053 D-Luciferin D-Luciferin is a light-emitting compound, also a natural substrate of luciferases.
M9052 ST2825 ST-2825 is MyD88 inhibitor.


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