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Cat.No.  Name Information
M6195 Propofol Propofol inhibited tumor size, cell viability and promoted cell apoptosis via inhibiting mTOR/p70S6K pathway mediated by HOTAIR in cervical cancer.
M6194 Esomeprazole Magnesium trihydrate Esomeprazole Magnesium trihydrate is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.
M6193 Propacetamol Hydrochloride Propacetamol is water soluble and can be directly injected.
M6192 Cetilistat Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.
M6191 Velpatasvir Velpatasvir is a second-generation NS5A inhibitor that inhibits hepatitis C viral replication through acting on the crucial "membranous web" that facilitates RNA replication.
M6190 Calcium-Sensing Receptor Antagonists I Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors.
M6189 AS101 AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
M6188 QS11 QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.
M6187 SM-164 SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
M6186 TPX-0005 TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 5.3 nM, 1.01 nM, 1.26 nM and 1.08 nM for SRC, WT ALK, ALK G1202R and ALK L1196M, respectively.
M6185 YM-58483 YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals.
M6184 Deutetrabenazine Deutetrabenazine is the deuterium labeled Tetrabenazine, which is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder.
M6183 7ACC2 7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. IC50 value: 11 nM ([14C]-lactate influx).
M6182 7ACC1 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters.
M6181 Anlotinib Anlotinib is a EGFR inhibitor extracted from patent 2015185012 A1, compound 1,which can be used to treat non-small cell lung cancer.
M6180 AZD3264 AZD3264 is a novel IKK2 inhibitor.
M6179 Diethylmaleate Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
M6178 Chidamide Chidamide is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
M6177 SGC2085 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >100-fold selective over other PRMTs.
M6176 TMP195 TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays.
M6175 Serabelisib Serabelisib (INK-1117,MLN-1117,TAK-117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
M6174 Avibactam sodium Avibactam sodium is a covalent, reversible β-lactamase inhibitor, inhibits β-lactamase TEM-1 and CTX-M-15 with IC50 of 8 nM and 5 nM, respectively.
M6173 AHU-377 hemicalcium salt AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
M6172 Isavuconazole Isavuconazole is a moderate inhibitor of CYP3A4 and a water-soluble triazole with broad-spectrum antifungal activity.
M6171 Solithromycin Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness.
M6170 Bedaquiline fumarate Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
M6169 FAAH-IN-2 FAAH-IN-2 is a potent FAAH(fatty acid amide hydrolase) inhibitor extracted from Patent WO/2008/100977A2.
M6168 LDK378 dihydrochloride LDK378 2Hcl (Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
M6167 Palbociclib Palbociclib is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.
M6166 Avastin Humanized vascular endothelial growth factor (VEGF) antibody (bevacizumab; Avastin) is a highly effective monoclonal antibody against metastatic colorectal cancer and several other advanced late stage cancers.
M6165 GSK 4716 GSK 4716 is a selective agonist with estrogen-related receptors ERRβ and ERRγ.
M6164 MCC950 MCC950 is a potent, selective NLRP3 inhibitor with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively.
M6163 MAK683 MAK683, an epigenetic drug for nasopharyngeal carcinoma, which is more prevalent in China than elsewhere, has entered Phase I clinical trials.
M6162 MTX-211 MTX-211 is a enamide hydrate.
M6161 GSK369796 GSK369796 shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain.
M6160 Bohemine An analog of aromatic cytokinins, the 2,6,9-trisubstituted purine derivative bohemine, was applied to cultures of mouse hybridoma cells in order to analyze its capacity of suppressing cell growth and maintaining or enhancing the production of monoclonal antibody.
M6159 GSK-2018682 This compound belongs to the class of organic compounds known as n-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 1-position.
M6158 ARQ-087 ARQ 087 is a novel, ATP competitive, small molecule, multi-kinase inhibitor with potent in vitro and in vivo activity against FGFR addicted cell lines and tumors. ARQ 087 exhibited IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3.
M6157 PX-102 PX-102, also known as PX20606, is a FXR agonist.
M6156 WZB117 WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 μM.
M6155 AR7 AR7 is a retinoic acid receptor α (RARα) antagonist.
M6154 2-PMPA 2-PMPA is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM.
M6153 E6005 RVT-501 (E6005) is a selective phosphodiesterase 4 (PDE4PDE4) inhibitor with an IC50 of 2.8 nM.
M6152 SF2523 SF2523 is a highly selective and potent inhibitor of PI3K with IC50 values of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.
M6151 LOXO-101 LOXO-101 is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.
M6150 GPR39-C3 GPR39-C3 is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.
M6149 HPI-4 HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
M6148 RS-1 RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer.
M6147 M2I-1 M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC.
M6146 TA 02 TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM. IC50 value: 20 nM. TA-02 is a novel compound with similar cardiogenic properties as SB203580 and SB202190. TA-02 especially inhibits TGFBR-2.
M6145 BMS-5 BMS-5 is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively).Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
M6144 BMS-3 BMS-3 is a potent inhibitor of LIMK1.LIM kinase 1 (LIMK1) activity is essential for cell migration and cell cycle progression.
M6143 SP2509 SP2509 is a selective histone demethylase LSD1 inhibitor with IC50 of 13 nM, showing no activity against MAO-A, MAO-B, lactate dehydrogenase and glucose oxidase.
M6142 XY1 XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.
M6141 NIBR189 NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).
M6140 TA 01 TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively).
M6139 GSK2256098 GSK2256098 is a potent, selective, reversible, and ATP competitive FAK kinase inhibitor with apparent Ki of 0.4 nM.
M6138 E-7046 E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities.
M6137 PF-05175157 PF-05175157 (Compound 9) is a potent Acetyl-CoA carboxylase (ACC1) inhibitor with IC50s of 23.5±1.1 nM (rat) and 27.0±2.7 nM (human).
M6136 Epacadostat Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
M6135 Calicheamicins The calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable.
M6134 Tildipirosin Tildipirosin is a derivative of the naturally occurring compound tylosin.
M6133 Oritavancin diphosphate Oritavancin is approved for the treatment of adult patients with acute bacterial skin and skin structure infections (SSSIs) caused by or suspected to be caused by susceptible isolates of designated gram-positive microorganisms.
M6132 ECBN HCL ECBN obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-d-glucan synthase.
M6131 Pristinamycin The pristinamycins exhibit a strong synergistic antibacterial activity against a wide range of Gram-positive and some Gram-negative bacteria, including methicillin- and vancomycin-resistant strains.
M6130 Zotarolimus Zotarolimus (ABT-578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.
M6129 Dalfopristin Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-drug resistant Enterococcus faecium infections.
M6128 BOC-D-FMK Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-α with an IC50 of 39 µM.
M6127 TD-4208 TD-4208 is a novel and potent muscarinic receptor antagonist that has a high affinity and long residence time at the M3 receptor, and demonstrates in vitro kinetic selectivity for M3 over M2 muscarinic receptor subtype and no meaningful off-target activity.
M6126 Triazolo-pyramidine derivative Triazolo-pyramidine derivative is a purine receptor antagonist.
M6125 AKP-11 AKP-11 has potent immune modulatory activity for treatment of EAE/MS, but with relatively low adverse effects suggesting AKP-11 as a potential therapeutic drug for MS patients.
M6124 Lubiprostone Lubiprostone is an orally active prostone that locally and selectively activates ClC-2 chloride channels to enhance the intestinal fluid secretion without altering the serum electrolyte levels.
M6123 Nandrolone phenylpropionate Nandrolone phenylpropionate (NPP) is an anabolic-androgenic steroid. The low androgenicity and enhanced anabolic activity of NPP has shown to positively influence calcium metabolism and to increase bone mass in osteoporosis.
M6122 ChlordehydroMethyl Testosterone Testosterone is normally present in the circulation of both men and women. Due to the dynamic regulation of endogenous testosterone production, including the acute effects of competition and exercise, testosterone concentrations may vary considerably within and among individuals.
M6121 Testosterone phenylpropionate Testosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester.
M6120 Testosterone isocaproate Testosterone Isocaproate help in increasing the body weight and will also help in gaining the strength and also help in losing fat in the body and gives an increase in libido, red blood cells, stamina and quick recovery after heavy training.
M6119 Testosterone Enanthate Androcur-treatment abolished testosterone-reduced cAMP, coupled with a changed expressional milieu of cAMP signaling elements. Results from in vitro experiments suggest that some of these effects are testosterone-AR dependent, while others could be due to disturbed LH and/or other signals.
M6118 666-15 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM.
M6117 Testosterone decanoate As with all forms of testosterone,Testosterone Decanoate will cause weight and strength gain, fat loss, a libido increase, an increase in IGF-1 levels, Red Blood Cell count, and of course increased recovery from training
M6116 Drostanolone Enanthate Drostanolone is one of the most frequently detected anabolic androgenic steroids in doping control analysis.
M6115 Drostanolone Propionate Drostanolone propionate can reduce the uptake of oestradiol-17B by tumour cells
M6114 Metandienone Metandienone is a synthetic anabolic steroid that is prohibited in sports by the World Anti-Doping Agency (WADA).
M6113 Hastatoside Hastatoside is isolated from Verbena species and exhibits various biological activities including sleep-promoting.
M6112 Thiamine chloride Thiamine chloride —the biologically active form of vitamin B1—is vital for all cellular life because it is a co-factor for several essential enzymes.
M6111 Meta-Fexofenadine Fexofenadine is a nonsedating antihistamine drug which is indicated for treatment of seasonal allergic rhinitis.
M6110 Levomefolic acid Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
M6109 Calcium N5-methyltetrahydrofolate Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.
M6108 Levomefolate calcium Levomefolate is an artificial form of folate.
M6107 Trenbolone Trenbolone(β-Trenbolone) is a steroid used by veterinarians on livestock to increase muscle growth and appetite.
M6106 17α-Methyltestosterone 17α-Methyltestosterone has similar binding affinity to AR and similar androgenic and anabolic activities as testosterone. IC50 value: 17 nM (Ki) Target:Androgen Receptor.
M6105 Testosterone Testosterone is an androgen, which binds the androgen receptor.
M6104 Ipilimumab Ipilimumab is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 kD.
M6103 Cetuximab Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation. MW : 145.781 KD.
M6102 Pembrolizumab Pembrolizumab is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. MW : 146.286 KD.
M6101 Atezolizumab Atezolizumab is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of PD-L2 with PD-1. MW : 145 KD.
M6100 Nivolumab Nivolumab is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1,PCD-1) with immune checkpoint inhibitory and antineoplastic activities. MW : 143.597 KD.
M6099 Boldenone Undecylenate Boldenone undecylenate(Equipoise) is a synthetic steroid which has a similar effect as the natural steroid testosterone.
M6098 Baicalein Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM.
M6097 Corynoxine Corynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
M6096 JQ-1 carboxylic acid (+)-JQ1 carboxylic acid is the carboxylic acid form of (+)-JQ1 for derivative synthesis.


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