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Cat.No.  Name Information
M21541 L-2-Aminooxy-3-phenylpropanoic acid L-2-Aminooxy-3-phenylpropanoic acid is an inhibitor of L-phenylalanine ammonia-lyase.
M21540 L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) is a long-term vitamin C derivative that can stimulate the expression and formation of collagen. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) can be used as a medium to supplement osteogenic differentiation of human adipose stem cells (hASCs). Increased alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation.
M21539 TC LPA5 4 TC LPA5 4 is a specific non-lipid LPA5 (GPR92) antagonist (IC50=0.8 μM in LPA5-RH7777 cells). Shows selectivity for LPA5 against 80 other screening targets.TC LPA5 4 was shown to inhibit LPA-induced aggregation of isolated human platelets.TC LPA5 4 inhibits proliferation and migration of thyroid cancer cells.
M21538 Diphenyl diselenide Diphenyl diselenide inhibits δ-aminolevulinic acid dehydrase (δ-ALA-D) in brain, liver, and kidney in vivo.
M21537 Urokinase Urokinase (urokinase) is a proteolytic enzyme. It can be used as a highly effective thrombolytic agent and also has a local vasodilating effect. Used as an antithrombotic compound.
M21536 BAY-069 BAY-069 is a branched-chain amino acid transaminase (BCAT) 1/2 inhibitor. Involved in the synthesis and catabolism of branched-chain amino acids.
M21535 UCB7362 UCB7362 is an oral plasma protease X (PMX) inhibitor that is being developed as an anti-malarial compound.
M21534 AN15368 AN15368 is an oral cleavage and polyadenylate specific factor (CPSF3) inhibitor being developed for use in Chagas disease (also known as American trypanosomiasis).
M21533 BI-0474 BI-0474 is a covalent KRASG12C inhibitor. The IC50 value for GDP-KRAS::SOS1 protein-protein interaction was 7.0 nM. BI-0474 also showed better antitumor activity in non-small cell lung cancer xenograft models.
M21532 JNJ-64264681 JNJ-64264681 is a covalent Bruton tyrosine kinase (BTK) inhibitor under development for hematological malignancies.
M21531 GDC-2394 GDC-2394 is an oral inhibitor of NLRP3 inflammasome. The NLRP3 inflamome, the best studied and most characterized, also inhibits IL-1β with IC50 of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β).
M21530 Sebetralstat Sebetralstat is an oral, on-demand plasma adrenalin trophin (PKa) inhibitor for hereditary angioedema (HAE). It can be used in the study of acute attacks.
M21529 All-trans-retinal All-trans-retinal is one of the major vitamin A metabolites in the retina. It is converted into retinoic acid in the body by retinal dehydrogenase. It is an effective photosensitizer.*The compound is unstable in solutions, freshly prepared is recommended
M21528 1-Carbamoylcyclopropanecarboxylic acid
M21527 MES hydrate MES is a buffer solution. MES is an amphoteric ion N- substituted sulfamic acid with a morpholine ring. This composition does not form complexes with most metals used in environmental and biological research. It is soluble in water but extremely insoluble in lipids, and therefore unable to penetrate membranes.
M21526 Recombinant Human S100A11(E.coli ) The recombinant human protein S100-A11 was produced by the expression system of Escoli and the target gene Met1-Thr105 was expressed. Protein number: P31949.
M21525 Recombinant Mouse S100A11 (E.coli , N-6His) The recombinant mouse protein S100-A11 was produced by the Escoli expression system, and the target gene Met1-Ile98 was expressed with 6His marker at the n terminal. Protein number: P50543.
M21524 Lyso-Tracker Red Lyso-Tracker Red is an eosinophilic fluorescent probe with a maximum excitation wavelength of 577nm and a maximum emission wavelength of 590nm. Lyso-Tracker Red must be at very low concentrations (usually about 50nM) to achieve excellent selectivity.
M21523 FNDR-20123 free base FNDR-20123 free base is an effective, safe and first-in-class anti-malarial HDAC inhibitor with an IC50 of 31 nM for Plasmodium and 3 nM for human HDAC.
M21522 FNDR-20123 FNDR-20123 is an effective, safe and first-in-class anti-malarial HDAC inhibitor with IC50 of 31 nM for Plasmodium and 3 nM for human HDAC.
M21521 THZ-P1-2 THZ-P1-2 is a first-in-class, selective PI5P4K inhibitor with an IC50 of 190 nM for Pi5P4α.
M21520 Vemurafenib-d5 Vemurafenib (PLX4032; RG7204; RO5185426) is a first-in-class selective B-RAF inhibitor that inhibits the activity of RAFV600E and c-RAF-1 with IC50 at 31 nM and 48 nM, respectively.
M21519 U7D-1 U7D-1 is a first-in-class, potent and selective ubiquitin-specific protease 7 USP7 PROTAC depressant in RS4; The DC50 in 11 cells was 33 nM. U7D-1 has anti-cancer activity.
M21518 MRTX849 ethoxypropanoic acid LC-2 is a potent, first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50, between 0.25 and 0.76 μM).
M21517 Supinoxin Supinoxin (RX-5902) is a potent oral inhibitor of phosphorylated p68 RNA helicase (P-p68) and a first-in-class anti-cancer agent. Supinoxin induced apoptosis and inhibited the growth of TNBC cancer cell lines, with IC50 ranging from 10 nM to 20 nM.
M21516 PZ-128 PZ-128 (P1pal-7), a cell-penetrating peptide, is a first-in-class, specific and reversible protease activating receptor 1 (PAR1) antagonist. It has anti-platelet, anti-metastasis, anti-angiogenesis and anticancer effects.
M21515 Zetomipzomib maleate Zetomipzomib (KZR-616) maleate is a first-in-class inhibitor of immunoproteasome that selectively targets the immunoproteasome subunit LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50:131/179 nM=hLMP7/mLMP7). Potential of Zetomipzomib maleate for use in multiple autoimmune diseases.
M21514 Myristoleic acid Myristoleic acid is a tedecaenoic acid with double bonds at positions 9-10 and a Z configuration. Myristoleic acid, a cytotoxic component of Serenoa repens extract, can induce apoptosis and necrosis of human prostatic cells.
M21513 Vemurafenib-d7 Vemurafenib (PLX4032; RG7204; RO5185426) is a first-in-class selective B-RAF inhibitor that inhibits the activity of RAFV600E and c-RAF-1 with IC50 at 31 nM and 48 nM, respectively. Vemurafenib can induce autophagy.
M21512 SR-1114 SR-1114 is a first-in-class PROTAC ENL depressant. SR-1114 in MV4; ENL degradation was observed in 11, MOLM-13 and OCI/AML-2 cells with DC50 values of 150 nM, 311 nM and 1.65 μM, respectively.
M21511 RGLS4326 RGLS4326 (RG4326) is a first-in-class microRNA-17 (miR-17) oligonucleotide inhibitor. RGLS4326 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 acts on HeLa cells to inhibit the function of miR-17 with EC50 value of 28.3 nM.
M21510 Telaglenastat hydrochloride Telaglenastat (CB-839) hydrochloride is a pioneering (first-in-class), selective, reversible, orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride has IC50 values of 23 nM and 28 nM for endogenous glutaminase in the kidney and brain of mice, respectively. Telaglenastat hydrochloride also induces autophagy and has strong antitumor activity.
M21509 Afizagabar Afizagabar (S44819) is a first-in-class, competitive and selective α5-GABAAR antagonist with an IC50 value of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2.
M21508 Ibezapolstat Ibezapolstat (ACX-362E) is a first-of-its-kind (first-in-class) inhibitor of the orally active DNA polymerase IIIC (DNA pol IIIC) developed for use in the study of Clostridium difficile infection (CDI).
M21507 AS-99 TFA AS-99 TFA is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity. In vivo, AS-99 TFA blocked cell proliferation, induced apoptosis and apoptosis, down-regulated MLL fusion target genes, and alleviated leukaemia.
M21506 MD-222 MD-222 is a first-in-class, highly effective ProTAC-based MDM2 depressant. MD-222 has anti-cancer properties.
M21505 AS-99 AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with antileukemic activity.
M21504 AS-99 free base AS-99 is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity.
M21503 MRTX849 acid MRTX849 acid can be used to synthesize PROTAC LC-2. LC-2 is a potent, first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50, between 0.25 and 0.76 μM).
M21502 FBA-IN-1 FBA-IN-1 is a pioneer, covalent allosteric inhibitor of 1, 6-bisphosphate fructoalbinase (CaFBA) from Candida albicans. FBA-IN 1 inhibited the growth of azole resistant strain 103 with MIC80 of 1 μg/mL.
M21501 Monalizumab Monalizumab is a first-in-class immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab can be used in the study of head and neck squamous cell carcinoma (HNSCC).
M21500 Polmacoxib Polmacoxib (CG100649) is a first-in-class, orally active non-steroidal anti-inflammatory compound (NSAID) that acts as a dual inhibitor. It inhibited COX-2 (IC50 ~ 0.1 μg/ml) and carbonic anhydrase.
M21499 Rodatristat ethyl Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity.
M21498 Bemarituzumab Bemarituzumab (FPA144) is a first-in-class, humanized, afucosylated immunoglobulin G1 monoclonal antibody (mAb) directed against fibroblast growth factor receptor 2b (FGFR2b) with two mechanisms of action against FGFR2b-overexpressing tumors: inhibition of FGFR2b signaling and enhanced antibody-dependent cell-mediated cytotoxicity (ADCC).
M21497 Gemcabene calcium Gemcabene calcium (PD-72953 calcium), the pioneering (first-in-class) lipid-lowering agent, can lower density lipoprotein cholesterol (LDL-C), lower triglycerides, and increase high-density lipoprotein cholesterol (HDL-C), and lower pro-inflammatory acute phase proteins. C-reactive protein (CRP), which shows anti-inflammatory activity.
M21496 N106 N106 is a first-in-class SERCA2a SUMOylation activator of sarcoplasmic reticulum calcium ATPase (N106). N106 directly activates the SUMO activating enzyme E1 ligase. N106 can be used in heart failure research.
M21495 Firibastat Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats.
M21494 Sibofimloc Sibofimloc (CD-202) is a first-in-class, intestinal limiting and oral active inhibitor of FimH adhesion. Sibofimloc has antibacterial activity and is being developed for the study of inflammatory bowel disease (IBD).
M21493 Omadacycline mesylate Omadacycline (PTK 0796) mesylate, the first (first-in-class) orally active aminomethylcycline antibiotic, is a tetracycline antibiotic. Omadacycline mesylate can be used to study acute bacterial skin and skin structure infections, infectious pneumonia, and urinary tract infections.
M21492 Omadacycline Omadacycline (PTK 0796) tosylate, the first (first-in-class) orally active aminomethylcycline antibiotic, is a tetracycline antibiotic. Omadacycline tosylate can be used to study acute bacterial skin and skin structure infections, infectious pneumonia, and urinary tract infections.
M21491 Rimtuzalcap Rimtuzalcap (CAD-1883) is the first (first-in-class), selective small conductance calcium-activated potassium channel (SK channel) positive allosteric regulator. Rimtuzalcap can be used in the study of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA).
M21490 Omadacycline hydrochloride Omadacycline (PTK 0796) hydrochloride, as a tetracycline antibiotic, is the first (first-in-class) orally active aminomethylcycline antimicrobial agent. Omadacycline hydrochloride is used to study acute bacterial skin and skin structure infections, infectious pneumonia, and urinary tract infections.
M21489 Secukinumab Secukinumab (AIN457) is a high-affinity monoclonal antibody against interleukin (IL-17A). Secukinumab (AIN457) is a first-in-class anti-IL-17 agent in the study of plaque psoriasis, ankylosing spondylitis, and psoriatic arthritis.
M21488 CM-579 CM-579 is a first-in-class reversible dual inhibitor of G9a and DNA methyltransferase (DNMT) with IC50 values of 16 nM and 32 nM, respectively. It plays an active role in a variety of cancer cells.
M21487 Valemetostat tosylate Valemetostat tosylate (DS-3201 tosylate) is a first-in-class EZH1/2 inhibitor with IC50 < 10 nM. Valemetostat tosylate can be used in the study of relapsed and refractory peripheral T cell lymphoma.
M21486 CM-579 trihydrochloride CM-579 trihydrochloride is a dual inhibitor of G9a and DNA methyltransferase (DNMT), with IC50 values of 16 nM and 32 nM, respectively, as first-in-class, reversible. It plays an active role in a variety of cancer cells.
M21485 Acotiamide-d6 Acotiamide-d6 (Z-338-d6 free base) is a deuterium substitute of Acotiamide. Acotiamide is a first-in-class gastrointestinal motility compound with oral activity that has the potential to be used in functional dyspepsia.
M21484 MBC-11 trisodium MBC-11 trisodium is a first-in-class coupling of bone-targeted ethyl bisphosphonate covalently bound to the antimetabolite cytarabine (Ara-C). MBC-11 trisodium has the potential to be used in neoplastic bone disease (TIBD).
M21483 MBC-11 triethylamine MBC-11 triethylamine is the first (first-in-class), bone-targeted ethyl bisphosphonate covalently bound conjugate to the antimetabolite cytarabine (araC). MBC-11 triethylamine has the potential to be used in neoplastic bone disease (TIBD).*The compound is unstable in solutions, freshly prepared is recommended
M21482 MS117 MS117 is a first-in-class, cell-active, irreversible covalent inhibitor of protein arginine methyltransferase (PRMT6) with an IC50 value of 18 nM.
M21481 MBC-11 MBC-11 is a first-in-class, bone-targeted bisphosphonate conjugate covalently bound to the antimetabolite cytarabine (araC). MBC-11 has the potential to be used in neoplastic bone disease (TIBD).
M21480 Varlilumab Varlilumab (CDX-1127) is a first-in-class monoclonal antibody to human IgG1 against CD27. Varlilumab has antitumor activity.
M21479 Vocacapsaicin hydrochloride Vocacapsaicin (CA-008) hydrochloride, as a prodrug of capsaicin, is the first non-opioid TRPV1 agonist. Vocacapsaicin hydrochloride provides lasting pain relief.
M21478 ELX-02 disulfate ELX-02 disulfate (NB-124 disulfate) is a first-in-class synthetic eukaryotic ribosomal specific glycoside (ERSG) that can be used to study genetic diseases caused by nonsense mutations.
M21477 Vocacapsaicin Vocacapsaicin (CA-008), a prodrug of capsaicin, is the first (first-in-class) non-opioid TRPV1 agonist. Vocacapsaicin can provide lasting pain relief.
M21476 ELX-02 sulfate ELX-02 sulfate (NB-124 sulfate) is a first-in-class synthetic eukaryotic ribosome-specific glycoside (ERSG) that can be used to study genetic diseases caused by nonsense mutations.
M21475 Ganaplacide hydrochloride Ganaplacide (KAF156) hydrochloride is a first-in-class antimalarial compound with oral activity. Ganaplacide hydrochloride is active on a variety of plasmodium parasites, including drug-resistant parasites.
M21474 Nln activator 1 Nln activator 1 is a first-in-class peptide neurolysin activator with enhanced brain permeability and stability.
M21473 Padsevonil Padsevonil (UCB0942) is the first effective antiepileptic agent. Padsevonil can be used in the study of epilepsy.
M21472 Gemcabene Gemcabene (PD-72953) is a first-in-class PPARα agonist, lipid-lowering agent. It lowers density lipoprotein cholesterol (LDL-C), lowers triglycerides and increases high density lipoprotein cholesterol (HDL-C), and lowers the pro-inflammatory acute phase protein, C-reactive protein (CRP), showing anti-inflammatory activity.
M21471 Recombinant Human Transferrin (Mammalian, C-6His) Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1.
M21470 CDDO-dhTFEA CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound that effectively activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB.
M21469 Recombinant Human PD-1 (HEK293, His) Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators.蛋白序列:DNA 序列编码人 PD-1( NCBI Reference Sequence: NP_005009.2)表达带有 His 标签在 C 末端。
M21468 DDR1-IN-4 DDR1-IN-4 is an effective and selective inhibitor of disk peptide domain receptor 1 (DDR1) autophosphorylation, with IC50 values of 29 nM and 1.9 μM for DDR1 and DDR2, respectively.
M21466 Recombinant Rat TNF-α (P. pastoris) Recombinant rat tumor necrosis factor produced in Pichia pastoris α (rrTNF- α) It is a glycosylated polypeptide chain containing 157 amino acids. rrTNF- α It is a completely biologically active molecule. Accession # P20826。
M21465 Trans-Farnesol Trans-Farnesol is a signaling molecule that is derived from farnesyl diphosphate, an intermediate in the isoprenoid/cholesterol biosynthetic pathway.
M21464 FITC-Dextran (MW 10000) FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm).
M21463 Recombinant Human HB-EGF(E. coli ) The recombinant human HB-EGF protein (Escherichia coli cell) is a polypeptide chain containing 86 amino acids. RhHB-EGF is a completely bioactive molecule, and its molecular weight is 12-14kDa by reduction SDS-PAGE analysis. Accession # Q99075。
M21462 24-Norursodeoxycholic acid 24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties.
M21461 Hexadecanedioic acid Hexadecanedioic acid is a common saturated fatty acid. Hexadecanedioic acid and Sepharose 4B are bound by covalent bond, which is more specific than dye resin and can be used to remove serum albumin (SA) from plasma.
M21460 Cinnamoylglycine Cinnamoylglycine is a human urine metabolite, a glycine conjugate of cinnamic acid and. Cinnamoylglycine is used as a urine marker, which can be used as a marker for colonization of drug resistance after the antibiotic study period.
M21459 ICG-OSu ICG-OSu (ICG NHS ester) is a near infrared fluorescent agent with amine reactivity that is widely used in the design of in vivo imaging probes. Em >750 nm infrared, Ex >750 nm infrared.
M21458 TRV120056 TRV120056 is a GQ-biased agonist, and its molecular efficiency on AT1R-Gq fusion protein is 10 times that of AT1R-βarr2 fusion protein. Sequence: DRVYIHPG.
M21457 Recombinant Human Galectin 9 (Human Cells, C-6His) Recombinant human Galectin 9 is produced by the human cell expression system, and the target gene encoding Met1-Thr323 is expressed in the C-terminus with the 6His marker. Protein number: Q3B8N1-2.
M21456 Enavogliflozin Enavogliflozin (DPW-16001), an antidiabetic compound, is a first class selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor with oral activity.
M21455 Casimersen Casimersen (SRP-4045) is an antisense oligonucleotide of the subclass of phosphodiamide morphorph oligomers. Casimersen binds to exon 45 of dystrophin's precursor mRNA to restore the open reading frame (by skipping exon 45), resulting in an internally truncated but functional dystrophin. Casimersen can be used in the study of Duchenne muscular dystrophy (DMD).
M21454 Cyclohexanecarboxamide Cyclohexanecarboxamide is a useful chemical for research.
M21453 Polyethylenimine Linear Polyethylenimine Linear (PEI) is a cationic polymer with a molecular weight of 40,000 that forms a compound with nucleic acid and passes it into mammalian cells. Linear PEI transfection reagents are widely suitable.
M21452 Polyethylenimine Polyethylenimine is a surfactant that acts as a polyelectrolyte multilayer on a charged surface, providing that surface with a biocompatible coat.
M21451 Recombinant Human Cathepsin K protein(E.coli) Protein construction: The DNA sequence encoding human CTSK (Ala115-Met329) is fused with His tag. Accession #P43235.
M21450 ALM201 Sequence: IRQQPRDPPTETLELEVSPDPAS
M21449 Recombinant Mouse IL-21 (E.coli, N-6His) Recombinant mouse interleukin-21 was produced by the expression system of Escherichia coli. The target gene encoding Pro25-Ser146 was expressed by 6His marker at the n-terminal. Protein number: Q9ES17.
M21448 Recombinant Mouse IL-15RA (Mammalian, C-Fc) Recombinant mouse interleukin-15 receptor subunit α is produced by mammalian expression systems, and the target gene encoding Gly33-Lys205 is expressed with Fc tag at the C-terminal. Protein number: Q60819.
M21447 Amelparib Amelparib is a potent, water soluble PARP-1 inhibitor with oral activity.
M21446 AZD-9574 AZD-9574 is a potent blood-brain barrier permeability inhibitor of PARP1, showing > 8,000 times selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 selectively inhibits PARP1 at the SSB site. AZD-9574 is an anticancer compound that can be used in HRD+ breast cancer and advanced solid malignancies.
M21445 Recombinant Human OLR1 (Mammalian, C-6His) Recombinant human oxidized low density lipoprotein receptor 1 is produced by mammalian expression systems, and the target gene encoding Ser61-Gln273 is expressed with the 6His marker at the C-terminal. Protein number: P78380.
M21444 GP130 receptor agonist-1 GP130 receptor agonist-1 is a potent, brain-penetrant and orally active GP130 receptor agonist. GP130 receptor agonist-1 has a neuroprotective effect on NMDA-induced neurotoxicity.
M21443 β-Secretase Inhibitor IV β-Secretase Inhibitor IV is a cellular permeability inhibitor that binds to the active site of BACE-1 and blocks its proteolytic activity (IC₅₀= 15 nM in human BACE-1).
M21442 Recombinant Mouse G-CSF(CHO) Granulocyte Colony-Stimulating Factor (G-CSF), also known as CSF-3 and MGI-1G, is a cytokine and hormone belonging to the IL-6 superfamily. It is expressed by monocytes, macrophages, endothelial cells, fibroblasts and bone marrow stroma.Accession # P09920。
M21440 Sodium iodate Sodium iodate is an inorganic compound with the chemical formula NaIO3 and can be used as an oxidant.


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