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Cat.No.  Name Information
M7562 BX517 BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
M7561 GSK-2881078 GSK 2881078 is a selective androgen receptor modulator potentially for the treatment of cachexia. GSK 2881078 is a selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function.
M7560 Cenerimod Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM.
M7559 ON1231320 ON1231320, also known as GBO-006, is a Polo-like kinase 2 (PLK2) inhibitor. In vitro testing revealed that ON1231320 is a selective inhibitor of PLK2 with no inhibitory activity against PLK1, PLK3 and PLK4.
M7558 SD-06 SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). IC50 value: 170 nM Target: p38MAPK
M7557 ON123300 ON123300 is a potent inhibitor of CDK4, with an IC50 of 3.8 nM, with little inhibitory activity against CDKs 1,2,5 and 8.
M7556 G007-LK G007-LK is a potent and selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
M7555 SAR405 SAR405 is a PIK3C3/Vps34 inhibitor with an IC50 of 1.2 nM. SAR405 also is a proximal inhibitor of the autophagy machinery.
M7554 Fruquintinib Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively.
M7553 Farampator Farampator (CX-691;Org24448) is an AMPA receptor positive modulator.
M7552 ETH2120 Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc.
M7551 Solcitinib Solcitinib is a selective Janus kinase 1 (JAK1) inhibitor, for the treatment of psoriasis, lupus, and ulcerative colitis. Targer: JAK1
M7550 N-Acetylneuraminic acid N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
M7549 Acebilustat Acebilustat is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug.
M7548 A-1331852 A-1331852 is an orally available BCL-XL selective inhibitor with a Ki of less than 10 pM.
M7547 NOD-IN-1 NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 μM and 6.45 μM, respectively.
M7546 SMER 28 SMER28 is an autophagy activator acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
M7545 SKF-86002 SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes.
M7544 SUN11602 SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.
M7543 TP-808 TP808 is a useful intermediate for the synthesis of diverse tetracycline antibiotics.
M7542 SBC-115076 SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases. Target: PCSK9 in vivo: SBC-115076 lowers cholesterol levels in mice that are fed high fat diet.
M7541 TUG-770 TUG-770 is a highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist with EC50 of 6 nM for hFFA1.
M7540 Pancreatin Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.
M7539 AS1517499 AS1517499 is a novel and potent STAT6 inhibitor with an IC50 value of 21 nM.
M7538 Tenalisib Tenalisib (RP6530) is a potent and selective dual PI3Kδ/γ inhibitor with IC50 values of 24.5 nM and 33.2 nM for PI3Kδ and PI3Kγ, respectively. Its selectivity over α and β isoforms are more than 300-fold and 100-fold, respectively.
M7537 SNS-314 Mesylate SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively and less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2.
M7536 BMS-935177 BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.
M7535 HDM201 HDM201 is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
M7534 SSR240612 Treatment with the kinin B1 receptor antagonist, SSR240612, provided a protective effect against organ damage by interfering with multiple target functions, including the suppression of B1R-induced inflammation and platelet aggregation.
M7533 SHP099 hydrochloride SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M7532 KR-33493 KR-33493 is a potent inhibitor of Fas-mediated cell death (FAF1).
M7531 AZD4635 AZD4635 is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.
M7530 Anlotinib Dihydrochloride Anlotinib Dihydrochloride is a novel multi-target tyrosine kinase inhibitor that is designed to primarily inhibit VEGFR2/3, FGFR1-4, PDGFRα/β, c-Kit, and Ret.
M7529 Tris(2-carboxyethyl)phosphine hydrochloride Disufide crosslinks of cystines in proteins can be reduced to cysteine residues by TCEP (tris-(2-carboxyethyl)phosphine). Unlike DTT (dithiothreitol), TCEP does not contain thiols and therefore usually does not need to be removed prior to thiol modification.
M7528 Phosphatase Inhibitor Cocktail (EDTA-Free) AbMole Phosphatase Inhibitor Cocktail (EDTA-Free) is a mixture of protease inhibitors prepared by 8 independent protease inhibitors according to the optimized ratio. It is divided into A and B two tubes: A tube is a phosphate - root analogue to prevent the loss of phosphorylation of proteins and lipids , and B tube is a new natural product to provide more comprehensive protection for phosphatase.
M7527 Gilteritinib Gilteritinib is a potent FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively.
M7526 Linaclotide Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
M7525 6-Chloropurine 6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide.
M7524 Lanolin Lanolin is a wax secreted by the sebaceous glands of wool-bearing animals and used widely in the pharmaceutical and cosmetics industries.
M7523 Potassium acetate Potassium acetate is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
M7522 5-Phenyl-2,4-pentadienoic acid 5-Phenyl-2,4-pentadienoic acid is used as Synthetic building block, anti-malarial agent.
M7521 Methylparaben Methyl 4-hydroxybenzoate is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
M7520 Brivaracetam Brivaracetam is a racetam derivative with anticonvulsant properties, usually used in the treatment of partial-onset seizures.
M7519 Cyclen Cyclen is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
M7518 NGP 555 NGP 555 is a small-molecule modulator of γ-secretase and has been successful in achieving good oral absorption, brain penetration, CNS activity, and specificity for a lipid-based membrane target preclinically.
M7517 Acotiamide hydrochloride Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.
M7516 Cefotiam hydrochloride Cefotiam hydrochloride is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
M7515 Brivudine Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.
M7514 Cefcapene Pivoxil Hydrochloride Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
M7513 Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
M7512 Chlorotetracycline Chlortetracycline is a tetracycline antibiotic and commonly used to treat conjunctivitis in cats.
M7511 Ceftizoxime Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
M7510 α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
M7509 UNC0642 UNC0642 is a potent, selective inhibitor of histone methyltransferases G9a/GLP with IC50s less than 2.5 nM for G9a and GLP and shows more than 300-fold selective for G9a and GLP over a broad range of kinases, GPCRs, transporters, and ion channels.
M7508 JQ-EZ-05 JQ-EZ-05 is a specific and reversible EZH1/2 inhibitor.
M7507 10-Hydroxycamptothecin 10-Hydroxycamptothecin is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.
M7506 5-methoxyflavone 5-methoxyflavone is a novel DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity.
M7505 7-Ethylcamptothecin 7-Ethyl Camptothecin is an anti-cancer chemical that exhibits a strong activity against various murine tumors through Topo I (topoisomerase) inhibition.
M7504 CA3 CA3 has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties.
M7503 YM 511 YM 511 is a potent aromatase (CYP19) inhibitor.
M7502 YM 298198 hydrochloride YM 298198 hydrochloride is a highly potent, selective non-competitive mGlu 1 antagonist.
M7501 YM 022 YM 022 is a highly potent, selective non-peptide CCK 2 antagonist.
M7500 YK 3-237 YK 3-237 is a sIRT1 activator.
M7499 YE 120 YE 120 is a gPR35 agonist.
M7498 Y-26763 Y-26763 is a k ir6 (K ATP) channel opener.
M7497 Y 11 Y 11 is a potent and selective FAK inhibitor.
M7496 XRP44X XRP44X is a ras-Net pathway inhibitor.
M7495 X-Gal X-Gal is a used in cloning procedures with IPTG.
M7494 XE 991 dihydrochloride XE 991 dihydrochloride is a potent, selective K V7 (KCNQ) channel blocker; blocks M-currents.
M7493 XCT 790 XCT 790 is a selective ERRα inverse agonist.
M7492 XAP 044 XAP 044 is a potent and selective mGlu 7 antagonist.
M7491 WR 1065 WR 1065 is a p53 activator. Also ROS scavenger.
M7490 Withaferin A Withaferin A is a inhibits NF-κB activation.
M7489 Wiskostatin Wiskostatin is a n-WASP inhibitor; inhibits Arp2/3 activation.
M7488 WIN 64338 hydrochloride WIN 64338 hydrochloride is a bradykinin B 2 antagonist.
M7487 WIN 18446 WIN 18446 is a aLDH1a2 inhibitor.
M7486 WEB 2086 WEB 2086 is a potent PAF receptor antagonist.
M7485 WAY 208466 dihydrochloride WAY 208466 dihydrochloride is a selective 5-HT 6 agonist.
M7484 WAY 207024 dihydrochloride WAY 207024 dihydrochloride is a gnRH receptor antagonist.
M7483 WAY 200070 WAY 200070 is a selective ERβ agonist.
M7482 WAY 181187 oxalate WAY 181187 oxalate is a high affinity and selective 5-HT 6 agonist.
M7481 W-7 hydrochloride W-7 hydrochloride is a calmodulin antagonist. Inhibits myosin light chain kinase.
M7480 W-5 hydrochloride W-5 hydrochloride is a calmodulin antagonist.
M7479 VUF 8430 dihydrobromide VUF 8430 dihydrobromide is a potent, high affinity H 4 agonist.
M7478 VUF 5574 VUF 5574 is a potent, selective hA 3 antagonist.
M7477 VU 1545 VU 1545 is a mGlu 5 positive allosteric modulator.
M7476 VU 0483605 VU 0483605 is a positive allosteric modulator at mGlu 1.
M7475 VU 0469650 hydrochloride VU 0469650 hydrochloride is a potent and selective negative allosteric modulator of mGlu 1.
M7474 VU 0422288 VU 0422288 is a selective group III mGlu positive allosteric modulator.
M7473 VU 0409106 VU 0409106 is a potent and selective negative allosteric modulator at mGlu 5.
M7472 VU 0365114 VU 0365114 is a positive allosteric modulator of M 5 receptors.
M7471 VU 0364739 hydrochloride VU 0364739 hydrochloride is a potent and selective PLD2 inhibitor.
M7470 VU 0360223 VU 0360223 is a negative allosteric modulator at mGlu 5.
M7469 VU 0240551 VU 0240551 is a kCC2 inhibitor.
M7468 VU 0155041 sodium salt VU 0155041 sodium salt is a potent, positive allosteric mGlu 4 agonist.
M7467 VU 0155041 VU 0155041 is a potent, positive allosteric mGlu 4 agonist.
M7466 VTP 27999 trifluoroacetate VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor.
M7465 VPC 23019 VPC 23019 is a s1P 1 and S1P 3 antagonist.
M7464 VO-OHpic VO-OHpic is a potent PTEN inhibitor.
M7463 Veratridine Veratridine is a voltage-gated Na + channel opener.

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