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Cat.No.  Name Information
M9094 EG00229 Trifluoroacetate salt EG00229 Trifluoroacetate is the first small molecule inhibitor of the neuropilin-1 and VEGF-A interaction with an IC50 of inhibition of 8 uM (125I-VEGF binding to PAE/NRP1 cells).
M9093 DTT Dithiothreitol (DTT) is the common name for a small-molecule redox reagent known as Cleland's reagent; as a reducing or "deprotecting" agent for thiolated DNA.
M9092 Hemin chloride Hemin is an iron-containing porphyrinis potentially for the treatment of gastroparesis.
M9091 A-779 A-779 is a specific antagonist of G-protein coupled receptor (Mas receptor).
M9090 Tranylcypromine hemisulfate Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO).
M9089 SAR7334 SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.
M9088 SRI-011381 hydrochloride SRI-011381 hydrochloride is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease.
M9087 FICZ FICZ is a potent aryl hydrogen receptor (AhR) agonist.
M9086 NAD+ NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
M9085 Indoximod Indoximod, also known as NLG8189 and D-1MT is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor with a Ki value of 19 μM.
M9084 STING-Inducer-1 STING-Inducer-1 (ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes).
M9083 Disitertide Disitertide is a TGF-β1 inhibitor.
M9082 ISO-1 ISO-1, also known as MIF Antagonist, is a MIF inhibitor with an IC50 of 7 uM.
M9081 Sodium Stibogluconate Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase.
M9080 Substance P Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
M9079 Angiotensin-(1-7) Angiotensin (1-7) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7), inhibits purified canine angiotensin converting enzyme (ACE) activity with an IC50 of 0.65 μM.
M9077 MDK-6314 MDK-6314 (STAT5-IN-1) is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain, with an IC50 of 47 μM for STAT5β isoform.
M9076 NADPH tetrasodium salt NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes.
M9075 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt.
M9074 GSK872 GSK872 is a receptor interacting protein kinase-3 (RIP3) inhibitor, which inhibits kinase activity with an IC50 of 1.3 nM.
M9073 Apatinib Apatinib is a selective VEGFR2 inhibitor with IC50 of 1 nM.
M9072 ATP Adenosine triphosphate (ATP) is an adenine nucleotide containing three phosphate groups esterified to the sugar moiety.
M9071 Amyloid beta-peptide(25-35) Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide, has shown neurotoxic activities in cultured cells.
M9070 AMG 487 AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) with IC50 values of 8nM and 8.2nM for I-IP-10 and I-ITAC, respectively.
M9069 AS1842856 AS1842856 is a cell-permeable Foxo1 inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM.
M9068 Mitoquinone mesylate Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant.
M9067 TG-100572 hydrochloride TG-100572 hydrochloride is a potent and selective multi-targeted VEGFR2/Src kinase inhibitor.
M9066 PT2385 PT2385 is an orally active, selective inhibitor of hypoxia inducible factor (HIF)-2alpha, with a Ki value of less than 50 nM.
M9065 Ac-DEVD-CHO Ac-DEVD-CHO is a specific inhibitor of Caspase-3 with a Ki value of 230 pM.
M9064 Oxytocin acetate Oxytocin acetate is a mammalian neurohypophysial hormone.
M9063 TLR2-IN-C29 TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling.
M9062 Necrosulfonamide Necrosulfonamide is an MLKL inhibitor with IC50 value of 124 nM in human HT-29.
M9061 Dehydroepiandrosterone Dehydroepiandrosterone is an effective antiapoptotic factor.
M9060 RSL3 RSL3 is an inhibitor of the glutathione (GSH) peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system.
M9059 TBHQ TBHQ is an aromatic organic compound, as a selective inducer of Nrf2 in a preclinical model of ICH.
M9058 Varenicline hydrochloride Varenicline hydrochloride is a nicotinic receptor partial agonist.
M9057 XMU-MP-1 XMU-MP-1 is a potent and selective MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively.
M9056 Losartan Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
M9055 INT-777 INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM.
M9054 Valproic acid Valproic acid is an HDAC inhibitor with IC50 in the range of 0.5~2 mM.
M9053 D-Luciferin D-Luciferin is a light-emitting compound, also a natural substrate of luciferases.
M9052 ST2825 ST-2825 is MyD88 inhibitor.
M9051 FCCP FCCP is a mitochondrial uncoupling agent.
M9050 MHY1485 MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes.
M9049 MPTP HCl MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease.
M9048 Etomoxir Etomoxir is a potent inhibitor of carnitine palmitoyltransferase-I (CPT-1).
M9047 ARS-1630 ARS-1630 is a novel mutant K-ras G12C inhibitor.
M9046 ARS-1323 ARS-1323 is a novel inhibitor of mutant K-ras G12C.
M9045 ARS-1620 ARS-1620 is an atropisomeric selective KRAS-G12C inhibitor with desirable pharmacokinetics.
M9044 MIK665 MIK665 is an inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3).
M9043 INCB057643 INCB057643 is a novel BET inhibitor.
M9042 Prexasertib dihydrochloride Prexasertib dihydrochloride (LY2606368 HCl) is a potent and selective ATP competitive inhibitor of the Chk1 protein kinase with IC50s of <1 nM and 8 nM for CHK1 and CHK2, respectively.
M9041 PF-03084014 PF-03084014 (Nirogacestat) is a potent and selective γ-secretase inhibitor with IC50 of 6.2 nM.
M9040 EMA400 EMA400 is a potent and highly selective AT2R antagonist.
M9039 Cilofexor Cilofexor is a farnesoid X receptor (FXR) agonist.
M9038 Photochlor Photochlor is a lipophilic, second-generation, chlorin-based photosensitizer.
M9037 AMPPD AMPPD is a new biochemistry ultrasensitive alkaline phosphatase substrate.
M9036 DM1-SMCC DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make ADC.
M9035 WHI-P97 WHI-P97 is a JAK3 inhibitor with an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays.
M9034 Mitapivat Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor.
M9033 VH-298 VH-298 is a potent VHL inhibitor that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, with a Kd value of 80 to 90 nM.
M9032 ZINC00881524 ZINC00881524 is a potent and selective ROCK inhibitor.
M9031 6-Methylcoumarin 6-Methylcoumarin belongs to the class of organic compounds known as coumarins and derivatives.
M9030 Cefquinome sulfate Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic.
M9029 Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
M9028 Nifuratel Nifuratel is a local antiprotozoal and antifungal agent used in gynecology.
M9027 Piroctone Olamine Piroctone Olamine is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff, fungal infections.
M9026 AZD-5153 HNT salt AZD-5153 HNT salt is a potent, selective and orally available BET/BRD4 bromodomain inhibitor, disrupts BRD4 with an IC50 of 1.7 nM.
M9025 Idalopirdine hydrochloride Idalopirdine hydrochloride is a potent and selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM.
M9024 Afuresertib hydrochloride Afuresertib hydrochloride is an orally bioavailable, potent and ATP-competitive inhibitor of the serine/threonine protein kinase Akt with potential antineoplastic activity.
M9023 Ellipticine Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor.
M9022 SKF38393 HCl SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM.
M9021 BTTAA BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.
M9020 TAS-102 TAS-102 is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride.
M9019 SCH 619734 SCH-619734 is an orally bioavailable, centrally-acting, selective neurokinin 1 receptor (NK1-receptor) antagonist with a Ki of 0.66 nM.
M9018 Levobupivacaine Levobupivacaine is a reversible neuronal sodium channel inhibitor.
M9017 Bimiralisib Bimiralisib (PQR309) is an orally bioavailable inhibitor of PI3K and mTOR, with potential antineoplastic activity.
M9016 Ezutromid Ezutromid (also known as BMN-195 and SMT C1100) is a first orally bioavailable utrophin's translation modulator with EC50 of 0.4 uM.
M9015 GNE-495 GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
M9014 RO4987655 RO4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM.
M9013 R1487 Hydrochloride R1487 Hydrochloride is an orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase.
M9012 R112 R112 is an ATP-competitive inhibitor of Syk kinase with an IC50 of 226 nM.
M9011 PRX-08066 PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist with IC50 of 3.4 nM.
M9010 Crolibulin Crolibulin (also known as EPC2407 and crinobulin) is a small molecule tubulin polymerization inhibitor with potential antineoplastic activity.
M9009 Ponatinib hydrochloride Ponatinib hydrochloride is a potent, orally available multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
M9008 PLX7904 PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
M9007 PLX8394 PLX8394 is an orally bioavailable, potent and selective Raf inhibitor with IC50 of 5 nM.
M9006 NSC5844 NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.
M9005 NPS-1034 NPS-1034 is a dual inhibitor of Axl and MET with IC50 values of 10.3 and 48 nM, respectively.
M9004 WDR5-0103 WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 µM).
M9003 MS023 MS023 is a potent and selective, cell-active inhibitor of type I PRMTs with IC50s of 4-119 nM.
M9002 ML281 ML-281 is a potent ans selective STK33 inhibitor with IC50 value of 14 nM.
M9001 ML-265 ML-265 (TEPP-46) is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2).
M9000 ML-098 ML-098 is an activator of the GTP-binding protein Rab7 with EC50 value of 77.6 nM.
M8999 CCG-1423 CCG-1423 is a novel specific inhibitor of RhoA transcriptional signaling.
M8998 PIK-III PIK-III (also known as VPS34-IN2) is a potent and selective inhibitor of VPS34 enzymatic activity, with IC50s of 18 nM and 1.2 μM for VPS34 and PI(3)Kδ, respectively.
M8997 MK-1064 MK-1064 is a potent, selective and orally active Orexin OX2 Receptor Antagonist for the research of insomnia.
M8996 SAR-20347 SAR-20347 is a potent dual inhibitor of JAK1 and TYK2 with IC50 values of 23 and 0.6 nM, respectively.
M8995 THZ2 THZ2 (an analog of THZ1) is a potent and selective CDK7 inhibitor which overcomes the instability of THZ1 in vivo (IC50s: CDK7=13.9 nM; TNBC cells=10 nM).
M8994 AM095 free acid AM095 free acid is a potent LPA1 receptor antagonist which inhibited GTPγS binding to CHO cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73 μM, respectively.


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