|M13394||HDM201 (Siremadlin)||HDM201 (Siremadlin) is a novel, highly effective and selective inhibitor of P53-MDM2 interaction.|
|M13393||NVP-CGM097||NVP-CGM097 is a highly effective and selective MDM2 inhibitor with a Ki value of 1.3 nM.|
|M13392||GeA-69||GeA-69 is a cell-penetrating selective allosteric inhibitor targeting Macrodomain 2 (MD2) with a Kd of 2.1 µM.|
|M13391||RBN012759||RBN012759 is a potent, selective and orally active PARP14 inhibitor with IC50 values of <3 nM and 5 nM against the human and mouse catalytic domains, respectively. AIDS in the anti-tumor immune response.|
|M13390||C527||C527 is an inhibitor of pan-dub enzyme with an IC50 value of 0.88 μM.|
|M13389||ACBI1||ACBI1 is an effective and synergistic PROTAC inhibitor of SMARCA2, SMARCA4 and PBRM1, with DC50 of 6 nM, 11 nM and 32 nM in MV-4-11 cells, respectively. ACBI1 can induce antiproliferative effect and apoptosis.|
|M13388||RP-6306||RP-6306 is the only inhibitor of PKMYT1 currently available in the clinic, which is synthetically fatal to CCNE1 amplification, FBXW7 deletion or other specific mutations.|
|M13387||SNDX-5613||SNDX-5613 is an effective and selective Menin-MLL binding inhibitor with Ki of 0.15 nM. Sndx-5613 can be used to study MLL gene rearrangement in acute leukemia, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).|
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.