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Abmole Inhibitor Catalog 2015

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Cat.No.  Name Information
M5197 Amlexanox Amlexanox is a specific inhibitor of IKKε and TBK1.
M5196 Spautin-1 Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating activity of USP10 and USP13 with IC50 of ∼0.6-0.7 μM.
M5195 Okadaic acid Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively.
M5194 VU0357017 hydrochloride VU0357017 hydrochloride is a highly selective M1 agonist that appear to act at an allosteric site to activate the receptor.
M5193 KS176 KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter with IC50 values of 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays, respectively.
M5192 NSC59984 NSC59984 is a p53 pathway activator via induction of mutant p53 protein degradation and p73 activation.

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