All AbMole products are for research use only, cannot be used for human consumption.
GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 significantly attenuates bladder hyperactivity.
Bone Res. 2024 Mar 29;12(1):20.
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx
GsMTx4 purchased from AbMole
Front Immunol. 2023 May 16;14:1194662.
Macrophages induce gingival destruction via Piezo1-mediated MMPs-degrading collagens in periodontitis
GsMTx4 purchased from AbMole
| Molecular Weight | 4101.89 |
| Formula | C185H279N49O45S6 |
| CAS Number | 1209500-46-8 |
| Solubility (25°C) | Water 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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