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GsMTx4

Cat. No. M10039

All AbMole products are for research use only, cannot be used for human consumption.

GsMTx4 Structure
Synonym:

GsMTx-4

Size Price Availability Quantity
500ug USD 255  USD255 In stock
1mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity

GsMTx4 is a spider venom peptide that selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 significantly attenuates bladder hyperactivity.

Product Citations
Chemical Information
Molecular Weight 4101.89
Formula C185H279N49O45S6
CAS Number 1209500-46-8
Solubility (25°C) Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qian Liu, et al. Exp Mol Med. Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystitis

[2] Radhakrishnan Gnanasambandam, et al. Biophys J. GsMTx4: Mechanism of Inhibiting Mechanosensitive Ion Channels

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Keywords: GsMTx4, GsMTx-4 supplier, Peptides, inhibitors, activators

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