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| Cat.No. | Name | Information |
|---|---|---|
| M10166 | PLGA lactide:glycolide (75:25) | Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics. |
| M10165 | TPEN | TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. |
| M10164 | Icatibant (HOE 140) | Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor, with IC50 value of 1.07 nM and Ki value of 0.798 nM, respectively. |
| M10163 | Baloxavir marboxil | Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections. |
| M10162 | Elexacaftor (VX-445) | Elexacaftor (also known as VX-445 and WHO11180) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector which can restore Phe508del CFTR protein function. This compound is not chiral purity |
| M10161 | PACAP (1-38) | PACAP (1-38) is a highly potent PACAP receptor agonist (Kd = 100 pM), it stimulates adenylate cyclase and phagocytosis. |
| M10160 | Lasmiditan | Lasmiditan (COL-144; LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist, showed a K(i) value of 2.21 nM at the 5-HT(1F) receptor in vitro binding studies. |
| M10159 | Kaempferol 3-O-β-D-glucuronide | Kaempferol 3-O-β-D-glucuronide is a conjugated kaempferol metabolite, which has anti-inflammatory effect. |
| M10158 | AZ32 | AZ32 is an orally bioavailable and blood-brain barrier-(BBB)penetrating inhibitor of ATM with IC50 of <6.2 nM and 0.31 μM for ATM enzyme in cell. |
| M10157 | Seletalisib | Seletalisib (UCB5857) is a potent and selective PI3Kδ inhibitor, with IC50 of 12 nM. |
| M10156 | 5'-Deoxy-5'-(Methylthio)adenosine | 5'-Deoxy-5'-(Methylthio)adenosine, also known as MTA and Methylthioadenosine, is a naturally occurring sulfur-containing nucleoside present in all mammalian tissues. |
| M10155 | 4-Guanidinobutanoic acid | Gamma-Guanidinobutyric acid (4-GBA) is used to study intestinal transport by the human proton-coupled amino acid transporter(s) (hPAT1). |
| M10154 | Choline Glycerophosphate | Choline Glycerophosphate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. |
| M10153 | Guanidineacetic acid | Guanidinoacetic acid (Glycocyamine) is a metabolic intermediate product of glycine in the human body, it is the direct precursor of creatine biosynthesis. |
| M10152 | Naporafenib | Naporafenib (also known as LXH254) is an orally available inhibitor of C-Raf and B-Raf with potential antineoplastic activity. |
| M10151 | PF-04958242 | PF-04958242 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate-positive allosteric modulator. |
| M10150 | Poly-D-lysine hydrobromide | Poly-D-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-D-lysine to be in a crystalline form soluble in water. |
| M10149 | N-Acetyl-L-methionine | N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine. |
| M10148 | Juglone | Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity. |
| M10147 | WKYMVM TFA | WKYMVM TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist. |
| M10146 | TRV-120027 TFA | TRV-120027 (also known as TRV027) is an angiotensin II receptor type 1 (AT1R) antagonist and engages ß-arrestins while blocking G-protein signaling. |
| M10145 | Danicopan | Danicopan (also known as ACH-4471 and ACH-0144471) is a highly potent, orally active Factor D inhibitor. |
| M10144 | NNC0640 | NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM. |
| M10143 | AZ3451 | AZ3451 is a potent PAR2 (protease-activated receptor-2) antagonist with IC50 of 23 nM, which plays a part in inflammation response, apoptosis, autophagy and cellular senescence during Osteoarthritis (OA). |
| M10142 | SBI-553 | SBI-553 is a potent and effective, brain-penetrant and allosteric modulator of NTR1 with EC50 of 0.34 μM. |
| M10141 | ATI-2341 TFA | ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4). |
| M10140 | TLQP-21 TFA | TLQP-21 is a VGF-derived peptide, which protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis and increases energy expenditure and prevents early phase diet-induced diabetes. |
| M10139 | Anakinra | Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. |
| M10138 | Yamogenin | Yamogenin (Diosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. |
| M10137 | DOTMA | DOTMA is applied to DNA delivery. |
| M10136 | GSK717 | GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. |
| M10135 | EGNHS | Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent, it is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). |
| M10134 | (R)-3-Hydroxybutanoic acid | (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. |
| M10133 | (S)-3-Hydroxybutanoic acid | (S)-3-Hydroxybutanoic acid is a human metabolite. |
| M10132 | Inosine | Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose, with immunomodulatory, neuroprotective, and analgesic properties. |
| M10131 | Efinaconazole | Efinaconazole (KP-103) is a triazole antifungal, it also acts as a 14α-demethylase inhibitor. |
| M10130 | AZD0156 | AZD0156 is an orally bioavailable ataxia telangiectasia mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities. |
| M10129 | CCT245737 | CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor, with IC50 values of 1.3 nM, 2440 nM and 30 nM for CHK1, CHK2 and G2 check point abrogation, respectively. |
| M10128 | L189 | L189 is a novel human DNA ligase inhibitor with IC50s of 5 μM, 9 μM and 5 μM for hLigI, hLigIII and hLigIV, respectively. |
| M10127 | Azathramycin | Azathramycin is an antibiotic, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. |
| M10126 | H-151 | H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation. |
| M10125 | C-178 | C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation. |
| M10124 | Porcupine-IN-1 | Porcupine-IN-1 is a potent porcupine inhibitor with IC50 value of 0.5±0.2 nM. |
| M10122 | DSPE-mPEG2000 | DSPE-mPEG2000 |
| M10121 | DSPC | 1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) |
| M10120 | Soybean Lecithin | Soybean Lecithin is a natural emollient, emulsifier, anti-oxidant, and spreading agent, lecithin is a hydrophilic ingredient that attracts water and acts as a moisturizer, generally obtained for cosmetic products from eggs and soybeans. |
| M10119 | DOPC | 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) |
| M10118 | Vericiguat | Vericiguat is a potent and orally available stimulator of guanylate cyclase (sGC). |
| M10117 | Thioflavin T | Thioflavin T is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. |
| M10116 | LM10 | LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). |
| M10115 | Recombinant Murine TNFα Protein | TNF-α is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. |
| M10114 | PMX 205 Trifluoroacetate | PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor. |
| M10113 | BI01383298 | BI01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5). |
| M10112 | Cinromide | Cinromide is an inhibitor of epithelial neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.5 μM. |
| M10111 | Anti-human CD3 mAb | CD3 is an important marker of T cells, it is composed of five polypeptide chains: γ, δ, ε, ζ, and η. |
| M10110 | D-(+)-2-Phosphoglyceric Acid Sodium Hydrate | D-(+)-2-Phosphoglyceric Acid Sodium Hydrate |
| M10109 | SRT2183 | SRT2183 is a selective activator of Sirtuin-1 (SIRT1) with EC1.5 value of 0.36 μM. |
| M10108 | Indirubin-3'-monoxime | Indirubin-3'-monoxime is a potent GSK-3β inhibitor with IC50 of 22 nM, and inhibits Cdk5/p35, Cdk1/cyclin-B and Cdk2/cyclin-E with IC50s of 100, 180, 250 nM. |
| M10107 | Longdaysin | Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7. |
| M10106 | Neoruscogenin | Neoruscogenin is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1). |
| M10105 | PF670462 dihydrochloride | PF670462 is a potent and selective inhibitor of of CK1 delta and epsilon (CK1δ/ε). |
| M10104 | Abaloparatide | Abaloparatide is an analog of PTHrP (parathyroid hormone-related protein). |
| M10103 | Plecanatide | Plecanatide is a structural analog of human uroguanylin, and similarly to uroguanylin, plecanatide functions as a guanylate cyclase-C (GC-C) agonist. |
| M10102 | Calcitonin | Calcitonin is a single-chain polypeptide composed of 32 amino acid residues, the major physiological effects of calcitonin are inhibition of bone resorption and deposition of postabsorptive calcium into bone following a meal, which prevents postprandial hypercalcemia. |
| M10101 | Diallyl disulfide | Diallyl disulfide is naturally found in garlic, which may provide protection against cardiovascular disease. |
| M10100 | Opicapone | Opicapone, also known as BIA 9-1067, is a novel potent and selective catechol-O-methyltransferase inhibitor (COMT inhibitor). |
| M10099 | CAY10404 | CAY10404 is one of the most selective inhibitors of COX-2 (IC50 = 1 nM) over COX-1. |
| M10098 | 1,3-Dimethylthiourea | 1,3-Dimethylthiourea |
| M10097 | Apelin-13 TFA | Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. |
| M10096 | GLPG0974 | GLPG0974 is a potent and selective FFA2 (also called GPR43) antagonist. |
| M10095 | Orelabrutinib | Orelabrutinib is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). |
| M10094 | Picloram | Picloram (4-Amino-3,5,6-trichloropyridine-2-carboxylic acid) is a chlorinated systemic herbicide widely used for woody plant and broad-leaved weed control. |
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide is a potent NKT cell stimulator and selective CD1d ligand. |
| M10092 | Sulfo-NHS | Sulfo-NHS is a peptide condensing agent, can form a stable active ester intermediate, used to prepare hydrophilic active ester, for example as a protein cross-linking agent. |
| M10091 | Thymosin β4 acetate | Thymosin beta 4 is a potent regulator of actin polymerization in living cells. |
| M10090 | Latrunculin B | Latrunculin B inhibits actin polymerization in vitro. Latrunculin B disrupts microfilament-mediated processes. |
| M10089 | Exendin-3 (9-39) amide | Exendin-3 (9-39) amide is a specific and competitive GLP-1 receptor antagonist. |
| M10088 | NVS-ZP7-4 | NVS-ZP7-4 is a potent ZIP7 Inhibitor, which inhibits Notch signaling with IC50 of 0.13 uM in HES-Luc reporter gene assays, selectively induces apoptosis and ER stress. |
| M10087 | Ginkgolide K | Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. |
| M10086 | 2-Aminopurine | 2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes. |
| M10085 | Mycophenolate mofetil | Mycophenolate mofetil is an inhibitor of inosine monophosphate dehydrogenase (IMPDH). |
| M10084 | AMY-101 acetate | AMY-101 acetate is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM). |
| M10083 | MK-0557 | MK-0557 is a highly selective, orally administered neuropeptide NPY5R antagonist (Ki =1.6 nM). |
| M10082 | Amodiaquine | Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent. |
| M10081 | Omaveloxolone | Omaveloxolone (RTA-408) is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2). |
| M10080 | Saccharin 1-methylimidazole | Saccharin 1-methylimidazole (also known as SMI) is an activator for DNA and RNA synthesis. |
| M10079 | ACY-775 | ACY-775 is a potent and selective HDAC6 inhbiitor with IC50 of 7.5 nM. |
| M10078 | Palmitoleic acid (Liquid) | Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism. |
| M10077 | Colivelin | Colivelin is a brain penetrant neuroprotective peptide and a potent activator of STAT3. |
| M10076 | Collagenase I | Collagenase is a protease which cleaves the triple-helical protein called collagen. There are three types of tissue collagenases, and these belong to the matrix metalloproteinases (MMP) family. |
| M10075 | (+)-Biotinamidohexanoic acid hydrazide | Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins. |
| M10074 | Bupivacaine | Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker. |
| M10073 | HLCL-61 hydrochloride | HLCL-61 hydrochloride is a potent and selective, first-in-class protein arginine methyltransferase 5 (PRMT5) inhibitor. |
| M10072 | AFN-1252 | AFN-1252 (API-1252; Debio-1452) is an enoyl-(acyl-carrier protein) reductase fabl inhibitor. |
| M10071 | KO-947 | KO-947 is a potent and selective ERK inhibitor with slow dissociation kinetics. |
| M10070 | LX2343 | LX2343 is a BACE1 enzyme inhibitor with IC50 value of 11.43±0.36 μM, and it is a neuroprotective agent. |
| M10069 | LYN-1604 2HCl | LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. |
| M10068 | Triheptanoin | Triheptanoin (IND106011; UX007) is a fatty acid metabolic modulator. |
| M10067 | Ac4GalNAz | Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
| M10066 | AP1903 (Rimiducid) | Rimiducid (AP1903) is a lipid-permeable tacrolimus analogue acts by cross-linking the FKBP domains. |
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