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Cat.No.  Name Information
M10476 GDC-0575 (ARRY-575) GDC-0575 (ARRY-575, RG7741) is a potent and selective oral inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM.
M10475 Lifirafenib (BGB-283) Lifirafenib (BGB-283) is a novel potent and selective RAF Kinase and EGFR inhibitor with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
M10474 Delgocitinib (JTE-052) Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor with IC50 values of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.
M10473 MK-3118 MK-3118 is a novel glucan synthase inhibitor with activity against many echinocandin-resistant strains of Candida due to differential avidity for the target site compared to echinocandins.
M10472 AZD3759 hydrochloride AZD3759 hydrochloride is an orally available inhibitor of the epidermal growth factor receptor (EGFR) with potential antineoplastic activity.
M10471 MTI-31 (LXI-15029) MTI-31 (LXI-15029) is a novel low-toxicity mTORC1/mTORC2 inhibitor, demonstrated a potent mTOR binding affinity with >5000 fold selectivity over the related PI3K family isoforms. MTI-31 inhibited mTORC1- and mTORC2 function at ≤120 nM in cellular assays.
M10470 Raxatrigine hydrochloride Raxatrigine hydrochloride (GSK-1014802 hydrochloride) is a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker.
M10469 MCH TFA (human, mouse, rat) MCH TFA (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively.
M10468 N-Formyl-Met-Leu-Phe N-Formyl-Met-Leu-Phe (fMLP) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR), which can inhibit TNF-alpha secretion.
M10467 Phosphocreatine disodium Phosphocreatine disodium is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction, belongs to alpha amino acids and derivatives.
M10466 Recombinant Mouse Interleukin-4 (IL-4) (E. coli) Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression.
M10465 Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression.
M10464 EC5026 (BPN-19186) EC5026 (BPN-19186) is a first-in-class, potent and orally active soluble inhibitor of Epoxide Hydrolase (sEH). EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
M10463 DIMBOA DIMBOA is a powerful antibiotic present in maize, wheat, and related grasses, possess growth inhibitory properties against many strains of studied bacteria and fungi, such as Staphylococcus aureus, Escherichia coli as well as against Saccharomyces cerevisiae.
M10462 O-Acetyl-L-carnitine hydrochloride O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
M10461 Euparin Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor, which exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes.
M10460 Recombinant Rat Insulin-like Growth Factor-1 (E. coli) Recombinant Rat Insulin-like Growth Factor-1 belonged to the insulin gene family, it is mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro.
M10459 MSA-2 MSA-2 is an orally available non-nucleotide STING agonist with antitumor activity. MSA-2 shows EC50 values of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
M10458 Huwentoxin IV TFA Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM).
M10457 PEG400 PEG400 is a neutral and biocompatible hydrophilic polymer.
M10456 VPC-80051 VPC-80051 is a novel inhibitor of hnRNP A1 that targets the hnRNP A1 RBD.
M10455 SB-4 SB-4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM.
M10454 JC-1 Mitochondrial Membrane Potential Assay Kit JC-1 Mitochondrial Membrane Potential Assay Kit is a kit that uses JC-1 as a fluorescent probe to quickly and sensitively detect the transmembrane potential difference of tissues, cells or purified mitochondria. It can be used for early apoptosis detection.
M10453 LY518674 LY518674 is a potent and selective PPAR-alpha antagonist with EC50 of 42 nM for human PPARα.
M10452 PFE-360 PFE-360, also known as PF-06685360, is a potent and selective, brain penetrated inhibitor of LRRK2 kinase.
M10451 WRW4 WRW4 is a selective antagonist of formyl peptide receptor 1 (FPR1) signaling, it inhibits WKYMVm binding to FPR1 (IC50 = 0.23 μM).
M10450 D-Ribose 5-phosphate disodium D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP.
M10449 Oleic acid (Liquid) Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is also a Na+/K+ ATPase activator.
M10448 Myristic acid Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
M10447 DMPC 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has the ability to enhance the constancy and in vitro antiproliferative effect of carmofur.
M10446 1400W dihydrochloride 1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM.
M10445 Fluzoparib (SHR3162) Fuzuopali is a poly (ADP-ribose) polymerase inhibitor (PARP) inhibitor with IC50 of 1.46±0.72 nM for a cell‐free enzymatic assay, with superior antitumor activity.
M10444 Oteseconazole Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd <39 nM).
M10443 Linperlisib (YY-20394) Linperlisib, also known as YY-20394 and PI3Kδ-IN-2, is a potent and selective PI3Kδ inhibitor.
M10442 Minodronic acid Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells.
M10441 Tofogliflozin (hydrate) Tofogliflozin (CSG-452) hydrate is a potent and highly specific sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 value of 2.9 nM.
M10440 Luseogliflozin Luseogliflozin is a SGLT2 inhibitor, it reduced reabsorption of renal filtered glucose and decreased renal glucose threshold (RTG) in urine to increase urinary glucose excretion.
M10439 Evocalcet Evocalcet is a calcium-sensing receptor agonist.
M10438 BI 882370 BI 882370 is a highly potent and selective RAF inhibitor that binds to the DFG-out (inactive) conformation of the BRAF kinase.
M10437 PF-06700841 PF-06700841 is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. PF-06700841 also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.
M10436 Belzutifan (PT2977) Belzutifan (PT2977) is a second-generation orally active and selective HIF-2α inhibitor with an IC50 of 9 nM.
M10435 Difamilast Difamilast (OPA-15406) is a topical, highly selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor.
M10434 Olutasidenib (FT-2102) Olutasidenib (FT-2102) is a highly potent and selective, orally active, brain penetrant mutant Isocitrate dehydrogenase 1 (IDH1) inhibitor, with IC50 values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively.
M10433 Bozitinib (PLB-1001) Bozitinib (PLB-1001; CBT-101) is a highly selective, blood-brain barrier permeable c-MET kinase inhibitor.
M10432 Difelikefalin (CR-845; FE-202845) TFA Difelikefalin (CR-845; FE-202845) TFA is a peripherally restricted and selective agonist of kappa opioid receptor (KOR).
M10431 Recombinant Human Nesfatin-1 (E. coli) Recombinant Human Nesfatin-1 is a metabolic polypeptide and is the N-terminal region of the precursor protein, Nucleobindin2 (encoded by NUCB2 gene).
M10430 Recombinant Human TGF-α (E. coli) Recombinant Human TGF-α, also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells.
M10429 Ciprofloxacin hydrochloride Ciprofloxacin hydrochloride is a β-diketone antibiotic with a broad spectrum antibacterial activity.
M10428 N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) is an endogenous metabolite, it is the important constituent of brain heteropolysaccharides (glycoproteins).
M10427 OVA Peptide (257-264) TFA OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
M10426 1,3-Benzoxazole-6-carboxylic acid 1,3-Benzoxazole-6-carboxylic acid
M10425 Dimethyl succinate (Standard for GC) Dimethyl succinate is a biodegradable ester with low odor and low volatility and commonly serves as a flavoring agent that can be used in perfumery and personal are products, including skin-conditioning agents and emollient.
M10424 Deoxyartemisinin Deoxyartemisinin
M10423 DT2216 DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC).
M10422 Sodium bicarbonate Sodium bicarbonate is an inorganic salt used as a buffering agent and a pH adjuster, it also serves as a neutralizer.
M10421 Sodium citrate (dihydrate) Sodium citrate dehydrate is an anticoagulant and also used as a buffer and food preservatives.
M10420 Proglumide Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist.
M10419 Fmoc-Asn(Trt)-OPfp Fmoc-Asn(Trt)-OPfp is a non-essential amino acid.
M10418 Malvidin chloride Malvidin (chloride) is a bioactive compound demonstrates antioxidant capacity with free radical scavenging properties in vitro.
M10417 Delphinidin chloride Delphinidin (chloride) is an anthocyanidin, a natural plant pigment which can modulate JAK/STAT3 and MAPKinase signaling to induce apoptosis in HCT116 cells.
M10416 Ac4ManNAz Ac4ManNAz is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
M10415 Curdlan Curdlan is a polysaccharide produced by bacteria and a homopolymer of glucose with β-1,3-glucosidic linkage.
M10414 Fmoc-3VVD-OH Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
M10413 Boc-Val-Cit-PAB Boc-Val-Cit-PAB is a cleavable ADC linker used in making antibody-drug conjugates (ADCs).
M10412 Val-cit-PAB-OH Val-cit-PAB-OH is a cathepsin cleavable ADC peptide linker for making MC-​Val-​Cit-​PAB, which is also known as MC-​Val-​Cit-​PAB-OH.
M10411 Fmoc-Val-Cit-PAB-PNP Fmoc-Val-Cit-PAB-PNP is a cleavable peptide ADC linker which used in the synthesis of antibody-drug conjugates (ADCs).
M10410 Fmoc-Val-Cit-PAB Fmoc-Val-Cit-PAB-OH is a cleavable useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC).
M10409 Mc-Val-Cit-PAB Mc-Val-Cit-PAB is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs).
M10408 SuO-Val-Cit-PAB-MMAE SuO-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.
M10407 PNU-159682 PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes, it is a highly potent DNA topoisomerase I inhibitor with excellent cytotoxicity. PNU-159682 is a potent ADCs cytotoxin.
M10406 N3-PEG3-vc-PAB-MMAE N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker.
M10405 Fmoc-Val-Cit-PAB-MMAE Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADCs that consists of a ADC linker (Fmoc-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE).
M10404 Tosufloxacin tosylate hydrate Tosufloxacin tosylate hydrate is a fluoroquinolone antibacterial agent used to treat susceptible infections.
M10403 MC-Val-Cit-PAB-MMAF MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.
M10402 MC-GGFG-DX8951 MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.
M10401 SPDP Crosslinker SPDP crosslinker, or SPDP NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. *The compound is unstable in solutions, freshly prepared is recommended
M10400 Val-Cit-PAB-MMAE Val-Cit-PAB-MMAE is a MMAE derivative with a cleavable linker, which is useful to make MMAE conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended
M10399 LY-3310756 hydrochloride LY-3310756 hydrochloride
M10398 Mc-MMAE Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended
M10397 McMMAF McMMAF is a protective group-conjugated MMAF. *The compound is unstable in solutions, freshly prepared is recommended
M10396 Deruxtecan Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
M10395 MKC-3946 MKC-3946 is a potent IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.
M10394 FL118 FL118 is an inhibitor of human survivin expression, activating tumor suppressor p53 as a novel MOA in p53 wild-type cancer cells.
M10393 Eribulin mesylate Eribulin mesylate (E7389 mesylate) is a microtubule targeting agent that is used for the research of metastatic breast cancer.
M10392 Corticotropin Corticotropin (ACTH) is a polypeptide hormone extracted from the anterior lobe of the pituitary gland of mammals, acts on the adrenal cortex, and has the effect of promoting the proliferation of adrenal cortex tissue and the production and secretion of corticosteroids.
M10391 Osthole Osthole (Osthol) is a natural antihistamine alternative with potential inhibition of histamine H1 receptor activity.
M10390 Aminooxy-acetic acid (AOA) Aminooxy-acetic acid (AOA) is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that induces GABA accumulation in the brain. It also inhibits cystathionine β synthase (CBS) and cystathionine γ lyase (CSE) with IC50 values of 8.5 and 1.1 μM, respectively.
M10389 Aminoethoxyvinyl glycine hydrochloride Aminoethoxyvinyl glycine hydrochloride is an ethylene synthesis inhibitor. It is used to study the roles of ethylene in plant processes such as gravitropism and fasciation/cresting.
M10388 (+)-JQ1 PA (+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1 with IC50 of 10.4 nM.
M10387 Thalidomide-NH-CH2-COOH Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein.
M10386 MT-802 MT-802 is a potent BTK degrader based on PROTAC technology, it induces Bruton's tyrosine kinase (BTK) knockdown.
M10385 PROTAC KRASG12C Degrader-LC-2 PROTAC KRASG12C Degrader-LC-2 is a potent first-in-class PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 μM.
M10384 Homo-PROTAC pVHL30 degrader 1 Homo-PROTAC pVHL30 degrader 1 is a pVHL30 degrader based on PROTAC and a potent VHL inhibitor.
M10383 Homo-PROTAC cereblon degrader 1 (OUN20985) Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.
M10382 PROTAC SGK3 degrader-1 PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a potent SGK3 degrader, it is a PROTAC conjugate of the 308-R SGK inhibitor with the VH032 VHL binding ligand, targeting SGK3.
M10381 TD-165 TD-165 is a PROTAC-based cereblon (CRBN) degrader.
M10380 dBET57 dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.
M10379 BSJ-03-123 BSJ-03-123 is a novel, potent CDK6-selective small-molecule degrader (PROTAC).
M10378 Cycloleucine Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation.
M10377 AZD4205 AZD4205 is a novel potent and selective janus kinase 1 (JAK1) inhibitor, with IC50 value of 73 nM.

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