| Cat.No. | Name | Information |
|---|---|---|
| M58223 | Perfluorooctanesulfonamide | Perfluorooctanesulfonamide is a longer chain fluorinated surfactant used in polymers. Used in aqueous film firm-forming foam to extinguish hydrocarbon-based fires. |
| M58222 | Paclobutrazol (97%) | Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants. Paclobutrazol also has antifungal activities. |
| M58221 | QPX7728-OH disodium | Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range. |
| M58219 | TPE-MI | TPE-MI (Tetraphenylethene maleimide) is an aggregation-induced luminescent agent that stains living cells, can be used to capture cysteines in exposed unfolded proteins, and detects protein damage after dihydroartemisinin studies of malaria parasites. |
| M58218 | Galactose oxidase | Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide. Galactose oxidase is often used in biochemical studies. |
| M58216 | N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate | N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate is a chromogenic substrate for plasmin assay, serine protease enzyme activity and fibrinogenolytic assays. |
| M58215 | Asparagusic acid | Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is also a plant growth inhibitor. |
| M58214 | H3K4(Me2) (1-20) | H3K4(Me2) (1-20) is a histone peptide. H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. |
| M58213 | CAY10614 | CAY10614 is a potent TLR4 antagonist. CAY10614 inhibits the lipid A-induced activation of TLR4, with an IC50 of 1.675 μM. |
| M58212 | Heneicosane | Heneicosane is an aroma component isolated from Streptomyces philanthi RL-1-178 or Serapias cordigera. Heneicosane is a pheromone and inhibits aflatoxin production. |
| M58211 | Iobenguane sulfate | Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. |
| M58210 | ABMA | ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. |
| M58209 | Streptonigrin | Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, acts as a pan-PAD inhibitor with IC50s of 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD4, respectively. Streptonigrin possesses both anti-tumor and anti-bacterial activity. |
| M58208 | Ethylene-d4 glycol | Ethylene-d4 glycol |
| M58207 | 1,2-Dibromoethane-d4 | 1,2-Dibromoethane-d4 |
| M58206 | 24-epi-Castasterone | 24-epi-Castasterone, a brassinosteroid, is a nature product that could be isolated from Hydrodictyon reticulatwn. |
| M58205 | DDX3-IN-1 | DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 values of 50 and 36 μM for HIV and HCV, respectively. DDX3-IN-1 has antiviral activity. |
| M58204 | Cross-linked dextran G-25 | Cross-linked dextran G-25 (same as Sephadex G-25) is a dextran chromatography medium. Cross-linked dextran G 25 separates from 1 to 5 kD (spherical proteins) and can be used for the separation of peptides as well as for the desalting and buffer replacement of large molecule proteins. Particle size: 50-150 μm |
| M58202 | Hoechst S 769121 | Hoechst S 769121 (Nuclear yellow) is a DNA-selective dye that is used to label DNA content in live and fixed cells. Upon binding to DNA, nuclear yellow fluoresces, and this fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. Nuclear yellow displays excitation/emission maxima of 355/495 nm, respectively. |
| M58201 | HKGreen-4I | HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively. |
| M58200 | 14-3-3η Protein inhibitor 1 | 14-3-3η Protein inhibitor 1 is a 14-3-3η protein inhibitor with a KD of 35 µM. |
| M58199 | Musk ketone | Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. |
| M58198 | Recombinant Mouse Growth Hormone (E. coli) | Somatotropin (GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. |
| M58197 | Guanosine 5'-diphosphate disodium salt | Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). |
| M58196 | Isocostic acid | Isocostic acid is a kind of terpenoid. Isocostic acid has effective antifeedant and cytotoxic doses with EC50 of 0.5 μg/ml against L. decemlineata. |
| M58195 | FK 565 | FK 565 is an immunoactive peptide and a nucleotide-binding oligomerization domain (Nod)-1 ligand agonist. |
| M58194 | 2,4-D sodium salt | 2,4-D sodium salt is a selective herbicide for the control of broad-leaved weeds. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development. 2,4-D sodium salt can induce apoptosis. |
| M58193 | Recombinant Human Activin A Protein (HEK293) | Recombinant Activin A protein is a multifunctional cytokine belonging to transforming growth factor β (TGF β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis. |
| M58192 | Recombinant Human Wnt3a Protein (HEK293, C-hFc) | Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family. WNT signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues. |
| M58191 | Calphostin C | Calphostin C (PKF115-584) is a small molecule inhibitor of Wnt/beta-catenin/lef-1 signaling. Calphostin C is also a potent and specific inhibitor of protein kinase C. PKF115-584 efficiently killed CLL cells (LC(50)<1 microM), whereas normal B cells were not significantly affected. |
| M58190 | FBnG | FBnG is a component of non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS), which is associated with the biosynthesis of fabrubactin (FBN). |
| M58189 | DOTAP methylsulfate | DOTAP methylsulfate is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. |
| M58188 | 2-(piperidin-2-yl)-1H-indole | 2-(piperidin-2-yl)-1H-indole |
| M58185 | VU0810464 | VU0810464 is a potent and selective non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. VU0810464 displays nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels with improved brain penetration. |
| M58184 | Sulfo-Cy5 carboxylic acid | Sulfo-Cy5 carboxylic acid is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm). |
| M58183 | Recombinant Mouse IL-15 (E. coli, N-His) | Interleukin-15 (IL-15) is a 14-15 kDa glycoprotein with immune regulatory functions in many diverse cell types. As a pleiotropic cytokine, IL-15 mediates the crosstalk between innate immunity and adaptive immunity whose principal role is to kill virally infected cells. IL-15 plays a crucial role in the development, differentiation, and survival of NK cells. |
| M58182 | Ulodesine | Ulodesine is a purine nucleoside phosphorylase (PNP) inhibitor. Ulodesine inhibits PNP with IC50 value of 2.293 nM/L. |
| M58181 | Recombinant Mouse C3a (E. coli) | Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. |
| M58180 | 4-O-Galloylalbiflorin | 4-O-Galloylalbiflorin is a natural product that can be derived from the root of Paeonia lactiflora pall. |
| M58179 | Poly-L-ornithine hydrobromide | Poly-L-ornithine hydrobromide (L-Ornithine homopolymer hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Poly-L-ornithine hydrobromide has been used to coat coverslips in culture vessels for culturing neural progenitor cells. It has also been used to coat culture plates for culturing cerebral cells of mice. |
| M58178 | Lauryl maltose neopentyl glycol | Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes. |
| M58176 | Purpurogallin | Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 µM. Purpurogallin has antioxidant and anti-inflammatory effects. |
| M58173 | DL-3-Phenyllactic acid | DL-3-Phenyllactic acid (3-Phenyllactic acid, PLA) is a broad-spectrum antimicrobial compound. |
| M58172 | 3-Bromoisonicotinic acid | 3-Bromoisonicotinic acid can be used in the synthesis of amides, hydrazides, esters and other derivatives. |
| M58171 | 2-Nitrobenzoic acid | 2-Nitrobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| M58170 | 3,5-Dimethyl-4-methoxybenzoic acid | 3,5-Dimethyl-4-methoxybenzoic acid |
| M58169 | 5-Hydroxyferulic acid | 5-Hydroxyferulic acid is an important hydroxycinnamic acid compound and a metabolite in the phenylpropanoid pathway. It acts as a precursor for the biosynthesis of sinapic acid and functions as a non-esterified substrate for COMT. |
| M58168 | Lunularic acid | Lunularic acid is a bioactive chemical. |
| M58167 | Tafluprost acid | Tafluprost acid (AFP-172) is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor. |
| M58166 | Plazomicin | Plazomicin is a derivative of Sisomicin and a novel aminoglycoside antibiotic that binds to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis in a concentration-dependent manner, with broad-spectrum antimicrobial activity against aerobic Gram-negative bacteria, and can be used in studies related to pyelonephritis. |
| M58165 | Flavin adenine dinucleotide disodium | Flavin adenine dinucleotide disodium (FAD disodium) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. |
| M58164 | Caf1-IN-1 | Caf1-IN-1 is inhibitor for ribonuclease Caf1 with an IC50 of 0.59 µM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 µM. |
| M58163 | (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine | (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. |
| M58162 | LS-102 | LS-102 is a selective E3 ubiquitin ligase synoviolin (Syvn1) inhibitor. LS-102 inhibits the autoubiquitination of synoviolin with an IC50 of 35 μM. |
| M58161 | CMPD-39 | CMPD-39 is a selective USP30 inhibitor with an IC50 of 0.02 μM. CMPD-39 increases protein ubiquitination and accelerates mitophagy. |
| M58160 | 5-(N,N-Hexamethylene)-amiloride | 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively. |
| M58159 | C-021 dihydrochloride | C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. |
| M58158 | C-021 | C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. |
| M58156 | Recombinant Human PRDX6 Protein (E. coli, N-6His) | Peroxiredoxin 6 (PRDX6) belongs to the thiol-specific antioxidant protein family, it is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. |
| M58155 | 5-HT2B antagonist-1 | 5-HT2B antagonist-1 is an orally active 5-HT2B receptor antagonist with an IC50 value of 33.4 nM. |
| M58154 | Recombinant Mouse Galectin-1/LGALS1 Protein (E. coli) | Galectin-1/LGALS1 is a member of the galectins. Galectin-1 contributes to different steps of tumor progression including cell adhesion, migration, and tumor-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. |
| M58153 | L-Lactic dehydrogenase (rabbit muscle) | L-Lactic dehydrogenase is an enzyme that catalyzes the conversion of lactate to pyruvate. L-Lactic dehydrogenase also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids. L-Lactic dehydrogenase is used in the determination of pyruvate (used in conjunction with reduced coenzyme) and in the diagnosis of myocardial infarction and leukemia. |
| M58149 | Recombinant Vaccinia virus B18R (Mammalian, C-6His) | B18R is a type I interferon (IFN)-binding protein encoded by the B18R open reading frame in the Western Reserve strain of vaccinia virus. B18R has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. Secreted B18R binds to uninfected and infected cells. B18R presents at the cell surface and protects cells from the antiviral state. |
| M58148 | N-Dodecanoyl-L-Homoserine lactone | N-Dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa. |
| M58147 | Furanone C-30 | Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain. |
| M58146 | TLR4-IN-C34-C2-COOH | TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
| M58144 | Recombinant Human IL-1R1 (Mammalian, C-6His) | Interleukin 1 receptor, type I (IL-1R1) is an interleukin receptor that belongs to the interleukin-1 receptor family. IL-1R1 is an important mediator involved in many cytokine induced immune and inflammatory responses. It binds to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Recombinant IL1 receptor Type I is a potent antagonist of IL1 action. |
| M58143 | Dihydroxyacetone phosphate | Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle in plants and glycolysis. |
| M58141 | Recombinant Rat VEGF164 (CHO) | Vascular endothelial growth factor (VEGF/VEGF-A) is originally known as vascular permeability factor (VPF). VEGF-As are endothelial cell-specific mitogens with angiogenic and vascular permeability-inducing properties. It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. |
| M58140 | HwTx-IV | Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule. |
| M58139 | CP05 | CP05 (CRHSQMTVTSRL) is a peptide with high affinity to exosomal CD63. The specific exosomal anchor peptide CP05 acted as a flexible linker and effectively combined the engineered exosome nanoparticles with 3D-printed porous bone scaffolds. |
| M58138 | DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
| M58137 | L-Sepiapterin | L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. |
| M58135 | Recombinant Human DEFB3 (E. coli) | Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
| M58134 | Diphenyl-1-pyrenylphosphine | Diphenyl-1-pyrenylphosphine (DPPP) is a probe that reacts with hydroperoxides to yield the fluorescent molecule diphenyl-1-pyrenylphosphine oxide (DPPP-O). DPPP has also been used as a fluorescent probe for the detection of low density lipoprotein and cellular oxidation. Fluorescence of DPPP-O can be monitored using excitation and emission wavelengths of 351 nm and 380 nm, respectively. |
| M58133 | BAY-9835 | BAY-9835 is a potent and orally active ADAMTS7 and ADAMTS12 antagonist with IC50s of 6 nM and 30 nM, respectively. BAY-9835 is very selective against a range of off-targets and metalloproteases. |
| M58131 | ST-2560 | ST-2560 is a selective inhibitor of the NaV1.7 sodium channel with IC50 value of 39 nM in primates with ≥1000-fold selectivity over other isoforms of the human NaV1.x family. |
| M58130 | Zurletrectinib | Zurletrectinib (ICP-723) is a potent tyrosine kinase inhibitor. Zurletrectinib serves as an antineoplastic agent. Zurletrectinib can used for research of TRK-mediated related diseases. |
| M58129 | BIIB129 | BIIB129 is a covalent, selective inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. |
| M58128 | Recombinant Human MIA Protein (E.coli, C-6His) | Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an autocrine fashion and promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. |
| M58127 | Recombinant Human Progranulin Protein (HEK293, C-His) | Progranulin is also called Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. |
| M58126 | Deferoxamine | Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. |
| M58125 | Succinate/succinate receptor antagonist 1 | Succinate/succinate receptor antagonist 1 is a succinate/succinate receptor antagonist. Succinate/succinate receptor antagonist 1 blocks succinate signaling in gingival tissue. Succinate/succinate receptor antagonist 1 inhibits the activation of succinate receptor 1 (SucnRl) with an IC50 value of 20 μΜ. |
| M58124 | Conbercept | Conbercept (KH902) is a monoclonal antibody targeting VEGFRA fused to the IGHG1 Fc fragment. Conbercept is produced by the fusion of the second C-LIKE of FLT1 and the third and fourth C-LIKE of KDR with IGHG1 Fc. |
| M58123 | OICR-8268 | OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can be used in the development of DCAF1-based PROTACs. |
| M58122 | Licoricesaponin E2 | Licoricesaponin E2 is a triterpene saponinthat can be found in Glycyrrhiza inflata. |
| M58121 | Uralsaponin B | Uralsaponin B is a natural product. |
| M58120 | L-α-lysophosphatidylcholine (soybean) | L-α-lysophosphatidylcholine (soybean) |
| M58119 | Metyrosine | Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine significantly inhibits high COX-2 activity. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. |
| M58117 | D-(-)-Lactic acid sodium | D-(-)-Lactic acid sodium is an endogenous metabolite. |
| M58115 | Recombinant Human Bcl-2 Protein (E. coli, C-His) | B-cell leukemia/lymphoma 2, also known as Bcl-2, belongs to the Bcl-2 family. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor. |
| M58114 | Ceramides | Ceramides, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides is a main lipid component of the permeability barrier in epidermis. |
| M58111 | Lauroyl-L-carnitine chloride | Lauroyl-L-carnitine chloride can be used as an absorption enhancer. |
| M58110 | Recombinant Human RIPK3 Protein (E. coli, N-His) | RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury via mitochondrial dysfunction. The FAO-dependent RIPK3 mediates pathogenesis of acute lung injury. |
| M58109 | MMP-9 Inhibitor I | MMP-9 inhibitor I is a cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). MMP-9 inhibitor I also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations. |
| M58108 | SI-2 hydrochloride | SI-2 hydrochloride is a highly promising SRC-3 inhibitor (PPI) with acceptable oral availability, with IC50 values of 3-20 nM for breast cancer cell death. |
| M58107 | PD-1/PD-L1-IN-9 | PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model. |
| M58106 | NCT-505 | NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM. NCT-505 weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57, 22.8, 20.1, >57 μM, respectively. |
| M58105 | Lysozyme (Recombinant) | Lysozyme (EC 3.2.1.17) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. |
| M58104 | Nicotinic acid mononucleotide triethylamine | Nicotinic acid mononucleotide triethylamine is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide triethylamine is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
