Free shipping on all orders over $ 500

New Products


View the latest 100 products by date added
Cat.No.  Name Information
M55684 GLP-1R agonist GLP-1R agonist is a potent GLP-1R (glucagon-like peptide 1 receptor) agonist, with KB of 26.3 nM for the recombinant human receptor. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight.
M55683 U-50488H U-50488H is a selective κ-opioid receptor agonist. U-50488H is known to induce diuresis.
M55682 BCI-137 BCI-137 is a competitive AGO2 inhibitor, with an IC50 of 342 μM. BCI-137 tightly binds to several residues of the Mid domain.
M55681 Recombinant Human MMP13 Protein (E. coli, N-His) The MMP-13 protein plays a role in the degradation of extracellular matrix proteins, especially fibrillar collagen, fibronectin, TNC, and ACAN. It cleaves triple-helical collagen, preferentially cleaves type II collagen, and can also target other collagen types.
M55680 Recombinant Human PSA/KLK3 Protein (Mammalian, 244AA, C-6His) Recombinant Human PSA/KLK3 is a member of serine proteases having diverse physiological functions. Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.
M55679 Recombinant Human CA125 Protein (Mammalian, C-6His) CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion.
M55678 Dapagliflozin-3-O-β-D-glucuronide Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin, and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9).
M55677 DL-β-Phenylserine threo form DL-β-Phenylserine threo form
M55676 Calcium Levofolinate EP Impurity I Arfolitixorin is an antifolate modulator.
M55675 Monochlorobimane Monochlorobimane (Chlorobimane) is a fluorescent dye, which can be used to measure glutathione (GSH) in cellular assays (λex=380 nm, λem=470 nm).
M55674 Recombinant Mouse Neuroserpin Protein (HEK293, C-His) Neuroserpin, also known as SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system.
M55673 VJDT VJDT is a TREM1 inhibitor, it effectively blocks TREM1 signaling. VJDT inhibits tumor growth and has potential for study in cancer research.
M55670 Chamaejasmine Chamaejasmine is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L. Chamaejasmine has antitumor activity. Chamaejasmine induces cell apoptosis, autophagy and ROS production, and activates the activity of AMPK/mTOR signal pathway.
M55668 Recombinant Human PTGDS Protein (Mammalian, C-6His) Prostaglandin-D2 Synthase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes.
M55666 3-Chloro-4-hydroxyphenylacetic acid 3-Chloro-4-hydroxyphenylacetic acid is an auxin influx inhibitor. 3-Chloro-4-hydroxyphenylacetic acid is one of the major chlorinated metabolite of chlorotyrosine.
M55665 6-Furfurylaminopurine 6-Furfurylaminopurine is a purine natural endogenous plant hormone. 6-Furfurylaminopurine has the effect of promoting cell division and tissue differentiation; inducing bud differentiation and relieving apical dominance; delaying protein and chlorophyll degradation, with freshness preservation and antiflagellation; delaying the formation of isolates and increasing fruit set.
M55663 4-Chloroindole-3-acetic acid 4-Chloroindole-3-acetic acid is a plant growth regulator that promotes plant growth and development and regulates fruit growth, flowering and stress tolerance.
M55661 Recombinant Human IFNAR1 (Mammalian, C-6His) Interferon Alpha/Beta Receptor 1 (IFNAR1) interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2. Ligands associate with IFN-α/β R2, and this complex subsequently forms a stable ternary assembly with IFN-α/β R1. IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation.
M55660 MTX-531 MTX-531 is a first-in-class, potent and selective inhibitor of EGFR and PI3K, with IC50s of 14.7 nM and 1.1-233 nM (differ in subtype). MTX-531 can also act as a weak agonist of PPARγ, with the EC50 of 3.4 μM in 293H cells.
M55659 CY7-SE triethylamine CY7-SE triethylamine is a CY dye, often used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction.
M55658 ML-184 ML-184 (CID2440433) is a selective GPR55 agonist with an EC50 of 250 nM and exhibits >100-fold selectivity for GPR55 over GPR35, CB1 and CB2. ML-184(CID2440433) increases proliferation of neural stem cells and promotes neuronal differentiation in vitro.
M55657 MEISi-1 MEISi-1 is a homeodomain inhibitor of small molecule MEIS1 protein. MEISi-1 induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer.
M55656 CW 008 CW 008 is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice.
M55655 2-Me PeER 2-Me PeER is a rhodamine dye-based fluorescent probe that detects CYP3A4 activity. In fluorescence-activated cell sorting (FACS) based on CYP3A4 activity, homogeneous and functional human induced pluripotent stem cell (hiPSC)-derived hepatocytes and intestinal epithelial cells can be obtained with the aid of 2-Me PeER.
M55654 Kyoto probe 1 Kyoto probe 1 is a hiPSCs fluorescent probe. Kyoto probe 1 selectively labels human pluripotent stem cells. Kyoto probe 1 is primarily explained by the distinct expression patterns of ATP-binding cassette (ABC) transporters by hiPS cells and differentiated cells. Kyoto probe 1 (KP-1) rapidly distinguishes between human ES/iPS (hES/iPS) cells and their differentiated cells.
M55653 TCS 2210 TCS 2210 is a neuronal differentiation inducer in mesenchymal stem cells (MSCs).
M55652 (-)-Variabilin (-)-Variabilin promotes differentiation of neural stem cells into neurons. (-)-Variabilin is an Neurogenin2 (Ngn2) promoter activator isolated from Butea superba.
M55651 IM176OUT05 IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 is a high solubility biguanide.
M55650 Stemazole Stemazole is a protective agent that promotes stem cell survival. Stemazole has the protective effect of human embryonic stem cells (hESCs). Stemazole enhances clonal expansion of single cells and decreases apoptosis. Stemazole for the study of stem cell survival in starvation culture.
M55649 Monatepil maleate Monatepil maleate (AJ-2615) is a potent and orally active Ca2+-channel antagonist and a noncompetitive ACAT inhibitor. Monatepil maleate (AJ-2615) is also an α1-adrenoceptor antagonist.
M55647 (R)-NX-2127 (R)-NX-2127 (compound 28) is a first-in-class, orally bioavailable Bruton’s Tyrosine Kinase (Btk) degrader. (R)-NX-2127 mediates the degradation of transcription factors IKZF1 and IKZF3 through molecular glue interactions with the cereblon E3 ubiquitin ligase complex. NX-2127 degrades common BTK resistance mutants, including BTKC481S.
M55646 Recombinant Human CDH16 Protein (Mammalian, C-6His) Cadherin-16 (CDH16) is a single-pass type I membrane protein which contains six cadherin domains. CDH16 is exclusively expressed in kidney, where the protein functions as the principal mediator of homotypic cellular recognition. It plays a role in the morphogenic direction of tissue development.
M55644 Recombinant Human CDH17 Protein (Mammalian, C-6His) Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherin-17 plays a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.
M55643 SKLB-163 SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis.
M55641 Cantuzumab Cantuzumab is a monoclonal antibody that can binds the CanAg antigen.
M55640 TSQ TSQ is a cell penetrant and specific fluorescent zinc sensor that preferentially accumulates in islet cells in a zinc content dependent manner. TSQ is commonly used to assess isolated islet purity.
M55639 2-NP-AOZ 2-NP-AOZ is a 2-nitrophenyl derivative of the tissue-bound metabolite, 3-amino-2-oxazolidinone (AOZ). 2-NP-AOZ may be used as a reference standard for the determination of 2-NP-AOZ in aquatic animals using enzyme linked immunosorbent assay (ELISA).
M55637 TEI-9647 TEI-9647 is a Vitamin D3 Lactone analogue, and it is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9647 blocks both 1α,25(OH)2D3-mediated HL-60 cell differentiation and also activation of the luciferase reporter in COS-7 cells that has been transfected with the cDNA containing the DRE of the rat 25(OH)D3-24-hydroxylase gene and cDNA of the human vitamin D nuclear receptor.
M55634 Peanut agglutinin Peanut agglutinin (PNA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.). Peanut agglutinin (PNA) is a biological material or organic compound that can be used in life science research.
M55633 Thioglycollate Medium (without Agar) AbMole Thioglycollate Medium (without Agar) is a medium for sterility tests and the cultivation of microaerophilic and anaerobic organisms.
M55632 Recombinant Human IL-7 Protein (Mammalian, C-6His) Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
M55631 Recombinant Human IL-7 Protein (E. coli) Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
M55630 Recombinant Human Desmoplakin/DSP Protein (E. coli, N-His) DSP proteins are major components of desmosomes and are critical for the structural integrity of various tissues. In cardiomyocytes, DSP regulates profibrotic gene expression through MAPK14/p38 MAPK activation and increased TGFB1 protein.
M55629 MIPS-21335 MIPS-21335 is a PI3KC2α inhibitor, with IC50 of 7 nM. MIPS-21335 also inhibits PI3KC2β, p110α, p110β and p110δ with IC50 values of 0.043, 0.140, 0.386, 0.742 μM, respectively.
M55628 ZLY28 ZLY28 is a first-in-class intestinal restricted and orally active FXR and FABP1 dual modulator. ZLY28 is also a novel anti-NASH agent.
M55627 RO-275 RO-275 is a potent, selective and orally active HCN1 inhibitor with IC50 values of 0.046, 14.3, 4.6, 13.9 µM for HCN1, HCN2, HCN3, HCN4, respectively. The selective HCN1 inhibitor RO-275 improved performance in a translationally relevant touchscreen task of WM (TUNL) in rats.
M55626 INS018 055 INS018 055 is a TNIK and MAP4K4 inhibitor with IC50 values of 12-120 nM, respectively. INS018 055 exhibits anti-fibrotic activity across different organs in vivo through oral, inhaled or topical administration. INS018 055 possesses anti-inflammatory effects in addition to its anti-fibrotic profile, validated in multiple in vivo studies.
M55625 XRD-0394 XRD-0394 is a potent and specific, orally bioavailable dual inhibitor of ATM and DNA-PKcs. XRD-0394 significantly enhanced tumor cell kill in the setting of therapeutic ionizing irradiation in vitro and in vivo. XRD-0394 also potentiates the effectiveness of topoisomerase I inhibitors in vitro.
M55624 BN-104 BN-104 (BNM-1192) is a novel, potent and highly selective, oral menin inhibitor. BN-104 (BNM-1192) can inhibit the Menin-MLL interaction.
M55623 Gly-Pro-AMC hydrobromide Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity. Gly-Pro-AMC hydrobromide have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 350 nm, fluorescence emission spectrum detection 450 nm.
M55622 Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His) BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-β) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion.
M55621 Recombinant Human ACVR2A Protein (Mammalian, C-6His) Activin Receptor Type-2A (ACVR2A) is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.
M55581 PT-179 PT-179 is an orthogonal Thalidomide (M2225) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.
M55580 Cobalt chloride hexahydrate Cobalt chloride has several applications. It is used in hygrometers; as a humidity indicator; as a temperature indicator in grinding; as a foam stabilizer in beer; in invisible ink; for painting on glass; in electroplating; and a catalyst in Grignard reactions, promoting coupling with an organic halide. It also is used to prepare several other cobalt salts; and in the manufacture of synthetic vitamin B12.
M55579 GLP-26 GLP-26 is an HBV capsid assembly modulators (CAM), inhibits HBV DNA replication (IC50=3 nM) in Hep AD38 system, and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.
M55578 UZH1a UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity.
M55577 Biotin-aniline Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA.
M55575 Timcodar mesylate Timcodar mesylate (VX-853-2) is a macrolide agent and mammalian multidrug-resistant bacterial efflux pump inhibitor that directly inhibits ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae.
M55574 Timcodar Timcodar (VX-853) is a macrolide agent and mammalian multidrug-resistant bacterial efflux pump inhibitor that directly inhibits ethidium bromide efflux in Staphylococcus aureus. Timcodar has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae.
M55573 ACBI3 ACBI3 (compound 7) is a pan-KRAS degrader. ACBI3 achieves in vivo degradation of oncogenic KRAS.
M55571 Empasiprubart Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation.
M55567 Recombinant Human ROR2 (Mammalian, C-6His) Receptor Tyrosine Kinaselike Orphan Receptor 2(ROR2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. ROR2 promotes osteogenesis, binds YWHAB and Interacts with WTIP.
M55566 EPIC-0628 EPIC-0628 is an inhibitor of the HOTAIR-EZH2 interaction and promotes ATF3 expression. EPIC-0628 EPIC-0628 also inhibits the ATF3-p38-E2F1 DDR pathway to inhibit the HR pathway and upregulates CDKN1A (p21) expression, causing cell cycle arrest.
M55565 ATF3 inducer 1 ATF3 inducer 1 is a potent ATF3 inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression.
M55560 Avacincaptad pegol sodium Avacincaptad pegol (ARC1905) is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b.
M55559 Recombinant Human IL-11 Protein (E. coli, N-His) Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation.
M55556 Recombinant Human IL-11 Protein (Yeast) Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation.
M55555 PI3K/Akt/CREB activator 1 PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway.
M55553 p-Cresyl sulfate potassium p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity. p-Cresyl Sulfate is a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.
M55552 Sodium Thioglycolate Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth. Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.
M55551 CID 2745687 CID 2745687 is a specific, reversible and competitive GPR35 antagonist with a Ki of 12.8 nM.
M55550 p-Cresyl sulfate p-Cresyl Sulfate is a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver.
M55549 Recombinant Mouse DPP-4/CD26 Protein (HEK293, N-hFc) Dipeptidyl peptidase-4 (DPP4, CD26) is a serine exopeptidase belonging to the S9B protein family. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV).
M55548 Amoxicillin-d4 Amoxicillin-d4
M55547 Cortisol-d5 Cortisol-d5
M55546 Vancomycin-d10 2TFA salt Vancomycin-d10 2TFA salt
M55545 Cyclosporin A-d4 Cyclosporin A-d4
M55544 Acetaminophen-d3 Acetaminophen-d3
M55543 Alosetron-13c,d3 Alosetron-13c,d3
M55542 Ritonavir-13c,d3 Ritonavir-13c,d3
M55541 Oseltamivir-13c,d3 Acid Oseltamivir-13c,d3 Acid
M55540 Benserazide-d3 HCl Benserazide-d3 HCl
M55539 Mometasone furoate-d3 Mometasone furoate-d3
M55538 Moxifloxacin-d4 Moxifloxacin-d4
M55537 Clevidipine-d7 Clevidipine-d7
M55536 Lamotrigine-13c,d3 Lamotrigine-13c,d3
M55535 Lumefantrine-d9 Lumefantrine-d9
M55534 Oseltamivir phosphate-d5 Oseltamivir phosphate-d5
M55533 Rifampicin-d8 Rifampicin-d8
M55532 DL-Tryptophan-d5 DL-Tryptophan-d5
M55531 L-Lysine 2HCl-d8 L-Lysine 2HCl-d8
M55530 N-Carbobenzyloxyglycine-d2 N-Carbobenzyloxyglycine-d2
M55529 AOZ-d4 AOZ-d4
M55528 Norverapamil-d7 Norverapamil-d7
M55527 SAR107375E Impurity 15-D11 SAR107375E Impurity 15-D11
M55526 SAR107375E Impurity 14-D8 SAR107375E Impurity 14-D8
M55525 SAR107375E Impurity 13-D8 SAR107375E Impurity 13-D8
M55524 2,2'-Bipyridyl-d8 2,2'-Bipyridyl-d8
M55523 Pyridin-3-ylmethanamine-d2 Pyridin-3-ylmethanamine-d2
M55522 PPCS-d9 PPCS-d9



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.