| Cat.No. | Name | Information |
|---|---|---|
| M59112 | BMS-984923 | BMS-984923 is a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling. |
| M59111 | Recombinant Human S100P (E. coli, N-6His) | Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca, S100P also binds Zn and Mg, and may play a role in the etiology of prostate cancer. |
| M59110 | Myoglobin (from equine skeletal muscle) | Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO2, MbO2 is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells. |
| M59109 | Hemoglobin (from bovine blood) | Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin is an inducer of HO-1. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. |
| M59108 | Pepsin (porcine stomach mucose) | Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin is a commonly used digestive enzyme for immunohistochemical procedures. |
| M59106 | 3-Fucosyllactose | 3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function. |
| M59105 | Ulocuplumab-MMAE | Ulocuplumab-MMAE is an antibody-drug conjugate (ADC). |
| M59104 | NEO214 | NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram and perillyl alcohol. NEO214 has anti-cancer activity and blood-brain barrier (BBB) permeability. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death. |
| M59103 | 123B9 | 123B9 is a tumor-homing agent, it is also a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. |
| M59102 | GW590735 | GW590735 is a potent and selective PPARα agonist. GW590735 shows an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. |
| M59101 | CCZ01048 TFA | CCZ01048 TFA is an α-MSH analogue, which exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. |
| M59100 | Lorvotuzumab-MMAE | Lorvotuzumab-MMAE is an antibody-drug conjugate (ADC). |
| M59099 | Yeast Nitrogen Base (Without Amino Acids and Ammonium Sulfate) | Yeast Nitrogen Base Without Amino Acids and Ammonium Sulfate is recommended to use for classifying yeasts based on their carbon and nitrogen requirements. The medium contains all essential nutrients required for the growth of yeasts except amino acids, histidine, methionine and tryptophan, and also ammonium sulphate. The addition of nitrogen and carbon sources is required. |
| M59098 | Hydronidone | Hydronidone is an orally active Pirfenidone derivative. Hydronidone is an inhibitor of phosphodiesterase-4 (PDE4) and cyclo-oxygenase (COX) as well as TGF-β. Hydronidone induces mitochondrial dysfunction and triggers apoptosis. |
| M59096 | Gentisuric Acid | Gentisuric Acid is a metabolite of Aspirin, it is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C. |
| M59095 | 5α-Dihydroprogesterone | 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) is the endogenous progesterone metabolite. 5α-Dihydroprogesterone (5a-Pregnane-3,20-dione) decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells. |
| M59093 | Anetumab-MMAE | Anetumab-MMAE is an antibody-drug conjugate (ADC). |
| M59092 | Diethylenetriaminepentaacetic dianhydride | Diethylenetriaminepentaacetic dianhydride (DTPA anhydride) is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. Diethylenetriaminepentaacetic dianhydride (DTPA anhydride) can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). |
| M59091 | Biotinylated-JQ1 | Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM. |
| M59090 | ML 2-14 | ML 2-14 is a E3-recruiting (RNF114, RNF4)-based PROTAC. ML 2-14 is targeting BRD4 with a C4 alkyl linker. ML 2-14 consists of the E3 ligase ligand EN219, the target protein ligand JQ-1, and the PROTAC linker. ML 2-14 can effectively degrade BRD4 in 231MFP breast cancer cells. |
| M59089 | 3,4-Benzopyrene | 3,4-Benzopyrene shows lung carcinogenicity in animal models. |
| M59088 | α-CGRP (mouse, rat) acetate | α-CGRP (mouse, rat) acetate is a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, it is a potent vasodilator. |
| M59087 | Praluzatamab-MMAE | Praluzatamab-MMAE is an antibody-drug conjugate (ADC). |
| M59086 | Adenosine 2',3'-cyclic phosphate sodium | Adenosine 2',3'-cyclic phosphate sodium serves as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. |
| M59085 | Poly-L-lysine (MW 70000~150000) | Poly-L-lysine is a positively charged amino acid polymer that can bind to DNA, red blood cell membranes, or any negatively charged protein. It is a non-specific cell adhesion factor that promotes cell adhesion to solid substrates. |
| M59084 | Ammonium chloride-15N | Ammonium chloride-15N is the 15N labeled Ammonium chloride. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor. |
| M59083 | Recombinant Human GSDMD Protein (E. coli, N-His) | GSDMD (Gasdermin D) is a protein that plays a crucial role in pyroptosis, a highly inflammatory form of cell death. It acts as a pore-forming protein, creating openings in the cell membrane and triggering the release of inflammatory molecules like interleukin-1β. |
| M59082 | Conoidin A | Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. |
| M59081 | 3-Phenylthiophene | 3-Phenylthiophene is a biochemical material that can be used in scientific research. 3-Phenylthiophene is a conducting polymer precursor. |
| M59080 | AV-153 free base | AV-153 free base is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. |
| M59079 | Creatine phosphokinase (rabbit muscle) | Creatine phosphokinase is an organ-specific enzyme that is mainly found in skeletal muscle, cardiac muscle, and brain tissue. Creatine phosphokinase (CPK) catalyzes the reversible reaction of creatine and ATP to form phosphocreatine and ADP. Creatine phosphokinase is a key enzyme for maintaining a constant ATP/ADP ratio during rapid energy turnover. |
| M59078 | 2-Methylthio-AMP | 2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation. |
| M59077 | Glucose-6-phosphate dehydrogenase | Glucose-6-phosphate dehydrogenase is used to convert p-glucose-6-phosphate to p-glucono-d-lactone-6-phosphate in presence of NADP+ or NAD+. Glucose-6-phosphate dehydrogenase can be used along with hexokinase in the determination of glucose from mice liver samples. |
| M59076 | Oregovomab-MMAE | Oregovomab-MMAE is an antibody-drug conjugate (ADC). |
| M59075 | Patritumab-MMAE | Patritumab-MMAE is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab attached to MMAE. |
| M59074 | pH Fluorescent Probe Red 600, SE | pH Fluorescent Probe Red 600, SE is a pH-sensitive fluorescent dye, the fluorescence intensity changes significantly with changes in the pH of the environment. pH Fluorescent Probe Red 600, SE is weakly fluorescent outside the cells, but its fluorescence is significantly enhanced in acidic compartments (such as phagosomes, lysosomes and endosomes). It can be used for multiplexing cellular functional analysis with green dyes such as GFP, Fluo-8, calcein, or FITC-labeled antibodies. Ex (nm) 576, Em (nm) 597 |
| M59073 | 6α-Hydroxy Paclitaxel | 6α-Hydroxy Paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy Paclitaxel (6-Hydroxytaxol) retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. |
| M59071 | Cu-ATSM | Cu-ATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. Cu-ATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities. |
| M59070 | Depatuxizumab mafodotin | Depatuxizumab mafodotin is an antibody-drug conjugate (ADC) which specifically targets the epidermal growth factor receptor (EGFR). Depatuxizumab mafodotin can induce cell death in glioma cell lines overexpressing EGFR or EGFRvIII. |
| M59069 | Depatuxizumab | Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. |
| M59067 | DSPE-PEG-FA | DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems. |
| M59066 | Ozuriftamab vedotin | Ozuriftamab vedotin (BA3021) is an antibody-drug conjugate (ADC), it is composed of receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab and VcMMAE. |
| M59065 | Lifastuzumab | Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody. |
| M59064 | Recombinant Human TSPAN13 Protein (E. coli, C-His) | Recombinant Human TSPAN13 Protein expressed the target gene encoding Cys94-Glu164 with a polyhistidine tag at the C-terminus. |
| M59063 | DSPE-Rhodamine | DSPE-Rhodamine is formed by the conjugation of DSPE with the Rhodamine fluorescent dye. DSPE possesses a hydrophobic lipid tail and a hydrophilic head group, while Rhodamine is a red fluorescent dye. DSPE-Rhodamine retains the lipid properties of DSPE while also imparting fluorescent labelling capabilities. As a key component of delivery systems, DSPE-Rhodamine enhances targeting and bioavailability. Its lipid properties facilitate the penetration of molecules through cell membranes, while its fluorescent properties enable tracking of distribution and dynamic changes within the body. |
| M59062 | Aloe Polysaccharide | Aloe Polysaccharides are the primary bioactive components of aloe vera gel, primarily found in the gel-like portion of the aloe vera leaf, specifically the transparent, viscous section enclosed by the leaf epidermis. Aloe polysaccharides are a large class of macromolecular compounds with diverse physiological functions, primarily composed of mannose, galactose, glucose, xylose, arabinose, and rhamnose, with mannose, galactose, and glucose being the most abundant. They exhibit various bioactivities, including antibacterial and anti-inflammatory effects, antiviral activity, immune modulation, antitumour properties, radiation protection, antioxidant properties, and hypoglycaemic effects. |
| M59061 | PF-03382792 | PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. |
| M59060 | LD540 | LD540 is a novel high-sensitivity lipophilic dye modified with BODIPY fluorescent groups, designed for precise labelling and imaging of lipid droplets. LD540 exhibits excellent photostability and an optimal fluorescence spectrum, making it compatible with various commonly used fluorescent dyes (such as DAPI and Alexa Fluor 647), thereby supporting multi-colour imaging requirements. Additionally, LD540 is suitable for both fixed and live cells and can label ultra-small lipid droplets. |
| M59059 | Recombinant Human SAA1 Protein (E. coli, N-6His) | Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. |
| M59056 | PDMPO | PDMPO (Yellow/Blue DND-160) is a ratiometric probe for the determination of lysosomal pH for fluorescence imaging. PDMPO exhibits pH-dependent dual excitation and dual emission peaks. PDMPO produces blue fluorescence (Ex/Em=329 nm/440 nm) in weakly acidic organelles, and in more acidic lysosomes it becomes yellow fluorescence (Ex/Em=384 nm/540 nm). |
| M59055 | GPVI antagonist 1 | GPVI antagonist 1 is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM. |
| M59054 | ENMD-1068 hydrochloride | ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. |
| M59053 | Potassium palmitate-13C16 | Potassium palmitate-13C16 can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. |
| M59052 | Palmitoyl-L-carnitine chloride | Palmitoyl-L-carnitine chloride (L-Palmitoylcarnitine chloride) is a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. Palmitoyl-L-carnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. |
| M59051 | 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt | 8-Azido-3,6-dioxaoctanoic Acid Cyclohexylamine Salt is a azido-modified PEG2 acid, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. |
| M59049 | (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of (-)-Blebbistatin. (-)-Blebbistatin is a selective inhibitor of myosin II ATPase. |
| M59048 | MPSD TFA | MPSD TFA (MARCKS-ED TFA) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition. |
| M59046 | Terminalia Chebula Extract | Terminalia Chebula Extract is extracted from Terminalia Chebula, which has antioxidant, hepatoprotective, neuroprotective, cytotoxic, antidiabetic, and anti-inflammatory activities. |
| M59044 | 3-Deoxyglucosone | 3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs). 3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion. 3-Deoxyglucosone is used as a biomarker for diabetes mellitus. |
| M59042 | 4-Nitro-2,1,3-benzoselenadiazole | 4-Nitro-2,1,3-benzoselenadiazole is a biochemical material that can be used in scientific research. |
| M59039 | αvβ1 integrin-IN-1 | αvβ1 integrin-IN-1 is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. αvβ1 integrin-IN-1 has antifibrotic effects. |
| M59038 | Flumethasone pivalate | Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Corticotropic hormone (GC) is an extremely important class of regulatory molecules in the organism, which plays an important role in the regulation of development, growth, metabolism, and immune function of the organism, and it is the most important regulatory hormone of the organism's stress response. |
| M59037 | Estramustine | Estramustine (LEO-275) is a nitrogen mustard linked to estradiol. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 μM for mitosis of DU 145 cells. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone. |
| M59036 | Copper probe CF4 | Copper probe CF4 (Copper fluor CF4) is a Cu+-specific fluorescent probe based on a rhodol dye scaffold. Copper probe CF4 (Copper fluor CF4) has high copper selectivity with a Kd value of 2.9×10-13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper probe CF4 (Copper fluor CF4) is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission). Copper probe CF4 (Copper fluor CF4) can be used to study colon cancer. |
| M59035 | Casein (from bovine milk) | Casein is a phosphorus-containing complex protein with α-casein and β-casein as its main components. Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein can be used in biochemical research, to formulate biological culture media, and as a thickener, emulsifier and stabiliser. |
| M59034 | Phalloidin-Fluor 647 Conjugate | Phalloidin-Fluor 647 Conjugate selectively binds to F-actins. Used at nanomolar concentrations, phalloidin derivatives are convenient probes for labeling, identifying and quantitating F-actins in formaldehyde-fixed and permeabilized tissue sections, cell cultures or cell-free experiments. |
| M59032 | SMS121 | SMS121 is a novel CD36 inhibitor. SMS121 reduced the uptake of fatty acid into AML cells that could be reversed by addition of free fatty acids and caused decreased cell viability. |
| M59031 | Z57346765 | Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes in PGK1 glycolysis and inhibits PGK1-dependent cell proliferation. Z57346765 induced expression changes of genes related to cell metabolism, DNA replication and cell cycle. |
| M59029 | HBC530 | HBC530 is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is nonfluorescent in solution, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm). |
| M59028 | 2',7'-dichlorodihydrofluorescein | 2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO-, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. The fluorescence intensity of DCF is positively correlated with the ROS concentration. |
| M59027 | Palmitic acid-13C16 | Palmitic acid-13C16 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. |
| M59026 | Recombinant Human TIMP-1 (HEK293, C-6His) | Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. |
| M59025 | Glucose isomerase | Glucose isomerase can catalyze the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. |
| M59023 | Gly-Phe-AFC | Gly-Phe-AFC is a fluorogenic, cell-permeant peptide substrate use to measure number of live cells in cytotoxic assay. It enters intact cells where it is cleaved to generate a fluorescent signal proportional to the number of living cells. |
| M59021 | DOPE-PEG2000-FITC | DOPE-PEG2000-FITC is a complex of DOPE, PEG2000 and FITC. DOPE-PEG2000-FITC has a wide range of applications in biomedical research, especially in the fields of drug delivery systems, cellular imaging and biomolecular labelling. |
| M59020 | Valsartan Ethyl Ester | Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist which can be used for the research of high blood pressure and heart failure. |
| M59019 | Enalapril | Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor. |
| M59018 | 4-Vinylsulfonylbenzoic acid | 4-Vinylsulfonylbenzoic acid is a biochemical material that can be used in scientific research. |
| M59017 | Diltiazem | Diltiazem is an orally active L-type Ca2+ channel blocker. Diltiazem shows antihypertensive and antiarrhythmic effects. |
| M59016 | Methionine sulfoximine | Methionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine. |
| M59015 | (R)-Zunsemetinib | (R)-Zunsemetinib is the isomer of Zunsemetinib, it can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. |
| M59014 | Rubrene | Rubrene is a reagent for chemiluminescence research and for transition metal complex ligation. |
| M59013 | Naphthacene | Naphthacene is a fused polycyclic aromatic compound exhibiting an electron field-effect mobility of approximately 10 cm2/Vs; it is an ethylnylated acene that functions as a conducting polymer, making it suitable for use as a donor material. Its exceptional photoluminescence and quantum yield position naphthacene as a highly promising candidate for the advancement of single crystal electronic materials. |
| M59012 | (2-Aminobenzyl)triphenylphosphonium bromide | (2-Aminobenzyl)triphenylphosphonium bromide is a biochemical material that can be used in scientific research. |
| M59010 | L-Glutamine-15N2 | L-Glutamine-15N2 is the 15N-labeled L-Glutamine. L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells. |
| M59009 | L-Phenylalanine-d8 | L-Phenylalanine-d8 is the deuterium labeled L-Phenylalanine. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. |
| M59008 | Recombinant Human IMPDH2 Protein (E. coli, N-His) | Recombinant Human IMPDH2 Protein (E. coli, N-His) expressed the target gene encoding Asp226-Phe514 with a His tag at the N-terminus. |
| M59005 | S-Me-DM4 | S-Me-DM4 is a metabolite of DM4 S-methylated by intracellular enzyme. |
| M59004 | 4-Hydroxyestradiol | 4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM. 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. |
| M59003 | D-Allulose | D-Allulose (D-Psicose) is an ultralow-energy monosaccharide sugar. It is a C-3 epimer of D-fructose, and is present in small quantities in agricultural products and commercially-prepared carbohydrate complexes. |
| M59002 | N,N-Dimethyltrifluoromethanesulfonamide | N,N-Dimethyltrifluoromethanesulfonamide (DMTMSA) is a trifluoromethanesulfonamide solvent. |
| M59000 | Eloralintide | Eloralintide (LY 3841136) is an AMYR agonist. |
| M58999 | PF-04745637 | PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1. |
| M58998 | TTBK1-IN-1 | TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. |
| M58997 | FASN-IN-4 tosylate | FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM. FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. |
| M58996 | Rolistobart | Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. |
| M58995 | β-Galactosidase (from Aspergillus oryzae) | β-Galactosidase acts on the terminal β-D-galactosyl moieties of disaccharides, glycoconjugates, and polysaccharides. It is useful in mediating transglycosylation reactions such as the synthesis of galactooligosaccharides (GOS). β-Galactosidases might be used for glycobiological and biotechnological applications. β-galactosidase cleaves lactose into its monosaccharide components, glucose and galactose. It also catalyses the transglycosylation of glucose into allolactose, the inducer of β-galactosidase, in a feedback loop. |
| M58994 | Cyanidin | Cyanidin is an antioxidant compound extracted from plants. It scavenges free radicals, inhibits xanthine oxidase activity, and protects DNA from cleavage. |
| M58993 | Safranal | Safranal is an orally active component of Saffron (Crocus sativus). Safranal has neuroprotective and anti-inflammatory effects and it can be used for the resaerch of Parkinson’s disease. |
| M58991 | Phenazopyridine | Phenazopyridine is a competitive SARM1 inhibitor, with IC50 145 μM. Phenazopyridine is a TRPM8 antagonist. Phenazopyridine can promote neuronal differentiation and it can also be used in the research of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases. |
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