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Cat.No.  Name Information
M10166 PLGA lactide:glycolide (75:25) Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics.
M10165 TPEN TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.
M10164 Icatibant (HOE 140) Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor, with IC50 value of 1.07 nM and Ki value of 0.798 nM, respectively.
M10163 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
M10162 Elexacaftor (VX-445) Elexacaftor (also known as VX-445 and WHO11180) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector which can restore Phe508del CFTR protein function. This compound is not chiral purity
M10161 PACAP (1-38) PACAP (1-38) is a highly potent PACAP receptor agonist (Kd = 100 pM), it stimulates adenylate cyclase and phagocytosis.
M10160 Lasmiditan Lasmiditan (COL-144; LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist, showed a K(i) value of 2.21 nM at the 5-HT(1F) receptor in vitro binding studies.
M10159 Kaempferol 3-O-β-D-glucuronide Kaempferol 3-O-β-D-glucuronide is a conjugated kaempferol metabolite, which has anti-inflammatory effect.
M10158 AZ32 AZ32 is an orally bioavailable and blood-brain barrier-(BBB)penetrating inhibitor of ATM with IC50 of <6.2 nM and 0.31 μM for ATM enzyme in cell.
M10157 Seletalisib Seletalisib (UCB5857) is a potent and selective PI3Kδ inhibitor, with IC50 of 12 nM.
M10156 5'-Deoxy-5'-(Methylthio)adenosine 5'-Deoxy-5'-(Methylthio)adenosine, also known as MTA and Methylthioadenosine, is a naturally occurring sulfur-containing nucleoside present in all mammalian tissues.
M10155 4-Guanidinobutanoic acid Gamma-Guanidinobutyric acid (4-GBA) is used to study intestinal transport by the human proton-coupled amino acid transporter(s) (hPAT1).
M10154 Choline Glycerophosphate Choline Glycerophosphate is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue.
M10153 Guanidineacetic acid Guanidinoacetic acid (Glycocyamine) is a metabolic intermediate product of glycine in the human body, it is the direct precursor of creatine biosynthesis.
M10152 Naporafenib Naporafenib (also known as LXH254) is an orally available inhibitor of C-Raf and B-Raf with potential antineoplastic activity.
M10151 PF-04958242 PF-04958242 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate-positive allosteric modulator.
M10150 Poly-D-lysine hydrobromide Poly-D-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-D-lysine to be in a crystalline form soluble in water.
M10149 N-Acetyl-L-methionine N-Acetyl-L-methionine, a human metabolite, is nutritionally and metabolically equivalent to L-methionine.
M10148 Juglone Juglone is a natural naphthoquinone found in the black walnut (Juglans regia) shows antimicrobial activity.
M10147 WKYMVM TFA WKYMVM TFA is a potent N-formyl peptide receptor (FPR1) and FPRL1/2 agonist.
M10146 TRV-120027 TFA TRV-120027 (also known as TRV027) is an angiotensin II receptor type 1 (AT1R) antagonist and engages ß-arrestins while blocking G-protein signaling.
M10145 Danicopan Danicopan (also known as ACH-4471 and ACH-0144471) is a highly potent, orally active Factor D inhibitor.
M10144 NNC0640 NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM.
M10143 AZ3451 AZ3451 is a potent PAR2 (protease-activated receptor-2) antagonist with IC50 of 23 nM, which plays a part in inflammation response, apoptosis, autophagy and cellular senescence during Osteoarthritis (OA).
M10142 SBI-553 SBI-553 is a potent and effective, brain-penetrant and allosteric modulator of NTR1 with EC50 of 0.34 μM.
M10141 ATI-2341 TFA ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4).
M10140 TLQP-21 TFA TLQP-21 is a VGF-derived peptide, which protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis and increases energy expenditure and prevents early phase diet-induced diabetes.
M10139 Anakinra Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R.
M10138 Yamogenin Yamogenin (Diosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay.
M10137 DOTMA DOTMA is applied to DNA delivery.
M10136 GSK717 GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor.
M10135 EGNHS Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable cross-linking reagent, it is mainly coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
M10134 (R)-3-Hydroxybutanoic acid (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase.
M10133 (S)-3-Hydroxybutanoic acid (S)-3-Hydroxybutanoic acid is a human metabolite.
M10132 Inosine Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose, with immunomodulatory, neuroprotective, and analgesic properties.
M10131 Efinaconazole Efinaconazole (KP-103) is a triazole antifungal, it also acts as a 14α-demethylase inhibitor.
M10130 AZD0156 AZD0156 is an orally bioavailable ataxia telangiectasia mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities.
M10129 CCT245737 CCT245737 is a potent, selective and orally active checkpoint kinase 1 (CHK1) inhibitor, with IC50 values of 1.3 nM, 2440 nM and 30 nM for CHK1, CHK2 and G2 check point abrogation, respectively.
M10128 L189 L189 is a novel human DNA ligase inhibitor with IC50s of 5 μM, 9 μM and 5 μM for hLigI, hLigIII and hLigIV, respectively.
M10127 Azathramycin Azathramycin is an antibiotic, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
M10126 H-151 H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
M10125 C-178 C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation.
M10124 Porcupine-IN-1 Porcupine-IN-1 is a potent porcupine inhibitor with IC50 value of 0.5±0.2 nM.
M10122 DSPE-mPEG2000 DSPE-mPEG2000
M10121 DSPC 1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC)
M10120 Soybean Lecithin Soybean Lecithin is a natural emollient, emulsifier, anti-oxidant, and spreading agent, lecithin is a hydrophilic ingredient that attracts water and acts as a moisturizer, generally obtained for cosmetic products from eggs and soybeans.
M10119 DOPC 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC)
M10118 Vericiguat Vericiguat is a potent and orally available stimulator of guanylate cyclase (sGC).
M10117 Thioflavin T Thioflavin T is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections.
M10116 LM10 LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively).
M10115 Recombinant Murine TNFα Protein TNF-α is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts.
M10114 PMX 205 Trifluoroacetate PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor.
M10113 BI01383298 BI01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).
M10112 Cinromide Cinromide is an inhibitor of epithelial neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.5 μM.
M10111 Anti-human CD3 mAb CD3 is an important marker of T cells, it is composed of five polypeptide chains: γ, δ, ε, ζ, and η.
M10110 D-(+)-2-Phosphoglyceric Acid Sodium Hydrate D-(+)-2-Phosphoglyceric Acid Sodium Hydrate
M10109 SRT2183 SRT2183 is a selective activator of Sirtuin-1 (SIRT1) with EC1.5 value of 0.36 μM.
M10108 Indirubin-3'-monoxime Indirubin-3'-monoxime is a potent GSK-3β inhibitor with IC50 of 22 nM, and inhibits Cdk5/p35, Cdk1/cyclin-B and Cdk2/cyclin-E with IC50s of 100, 180, 250 nM.
M10107 Longdaysin Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7.
M10106 Neoruscogenin Neoruscogenin is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1).
M10105 PF670462 dihydrochloride PF670462 is a potent and selective inhibitor of of CK1 delta and epsilon (CK1δ/ε).
M10104 Abaloparatide Abaloparatide is an analog of PTHrP (parathyroid hormone-related protein).
M10103 Plecanatide Plecanatide is a structural analog of human uroguanylin, and similarly to uroguanylin, plecanatide functions as a guanylate cyclase-C (GC-C) agonist.
M10102 Calcitonin Calcitonin is a single-chain polypeptide composed of 32 amino acid residues, the major physiological effects of calcitonin are inhibition of bone resorption and deposition of postabsorptive calcium into bone following a meal, which prevents postprandial hypercalcemia.
M10101 Diallyl disulfide Diallyl disulfide is naturally found in garlic, which may provide protection against cardiovascular disease.
M10100 Opicapone Opicapone, also known as BIA 9-1067, is a novel potent and selective catechol-O-methyltransferase inhibitor (COMT inhibitor).
M10099 CAY10404 CAY10404 is one of the most selective inhibitors of COX-2 (IC50 = 1 nM) over COX-1.
M10098 1,3-Dimethylthiourea 1,3-Dimethylthiourea
M10097 Apelin-13 TFA Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM.
M10096 GLPG0974 GLPG0974 is a potent and selective FFA2 (also called GPR43) antagonist.
M10095 Orelabrutinib Orelabrutinib is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).
M10094 Picloram Picloram (4-Amino-3,5,6-trichloropyridine-2-carboxylic acid) is a chlorinated systemic herbicide widely used for woody plant and broad-leaved weed control.
M10093 α-Galactosyl Ceramide α-Galactosyl Ceramide is a potent NKT cell stimulator and selective CD1d ligand.
M10092 Sulfo-NHS Sulfo-NHS is a peptide condensing agent, can form a stable active ester intermediate, used to prepare hydrophilic active ester, for example as a protein cross-linking agent.
M10091 Thymosin β4 acetate Thymosin beta 4 is a potent regulator of actin polymerization in living cells.
M10090 Latrunculin B Latrunculin B inhibits actin polymerization in vitro. Latrunculin B disrupts microfilament-mediated processes.
M10089 Exendin-3 (9-39) amide Exendin-3 (9-39) amide is a specific and competitive GLP-1 receptor antagonist.
M10088 NVS-ZP7-4 NVS-ZP7-4 is a potent ZIP7 Inhibitor, which inhibits Notch signaling with IC50 of 0.13 uM in HES-Luc reporter gene assays, selectively induces apoptosis and ER stress.
M10087 Ginkgolide K Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway.
M10086 2-Aminopurine 2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes.
M10085 Mycophenolate mofetil Mycophenolate mofetil is an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
M10084 AMY-101 acetate AMY-101 acetate is a peptidic inhibitor of the central complement component C3 (KD = 0.5 nM).
M10083 MK-0557 MK-0557 is a highly selective, orally administered neuropeptide NPY5R antagonist (Ki =1.6 nM).
M10082 Amodiaquine Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
M10081 Omaveloxolone Omaveloxolone (RTA-408) is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2).
M10080 Saccharin 1-methylimidazole Saccharin 1-methylimidazole (also known as SMI) is an activator for DNA and RNA synthesis.
M10079 ACY-775 ACY-775 is a potent and selective HDAC6 inhbiitor with IC50 of 7.5 nM.
M10078 Palmitoleic acid (Liquid) Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.
M10077 Colivelin Colivelin is a brain penetrant neuroprotective peptide and a potent activator of STAT3.
M10076 Collagenase I Collagenase is a protease which cleaves the triple-helical protein called collagen. There are three types of tissue collagenases, and these belong to the matrix metalloproteinases (MMP) family.
M10075 (+)-Biotinamidohexanoic acid hydrazide Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins.
M10074 Bupivacaine Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker.
M10073 HLCL-61 hydrochloride HLCL-61 hydrochloride is a potent and selective, first-in-class protein arginine methyltransferase 5 (PRMT5) inhibitor.
M10072 AFN-1252 AFN-1252 (API-1252; Debio-1452) is an enoyl-(acyl-carrier protein) reductase fabl inhibitor.
M10071 KO-947 KO-947 is a potent and selective ERK inhibitor with slow dissociation kinetics.
M10070 LX2343 LX2343 is a BACE1 enzyme inhibitor with IC50 value of 11.43±0.36 μM, and it is a neuroprotective agent.
M10069 LYN-1604 2HCl LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
M10068 Triheptanoin Triheptanoin (IND106011; UX007) is a fatty acid metabolic modulator.
M10067 Ac4GalNAz Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
M10066 AP1903 (Rimiducid) Rimiducid (AP1903) is a lipid-permeable tacrolimus analogue acts by cross-linking the FKBP domains.


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