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| Cat.No. | Name | Information |
|---|---|---|
| M21630 | NMS-P515 | NMS-P515 is a potent inhibitor of PARP-1 both in biochemical (Kd: 0.016 μM) and cellular (IC50: 0.027 μM) assays. |
| M21629 | 3,3-Dimethyl-1-butanol (liquid) | 3,3-Dimethyl-1-butanol (DMB) is an indirect inhibitors of TMAO, which can reduce plasma TMAO levels. 3,3-Dimethyl-1-butanol is a branched alkanol, which can be used as a ligand in the preparation of nickel based single-molecule magnets. |
| M21628 | 2'-Fucosyllactose | 2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines. |
| M21627 | Tautomycetin | Tautomycetin is a potent and specifical PP1 inhibitor with the potential apoptosis-inducing activity. Tautomycetin inhibits purified PP1 and PP2A enzymes with IC50s of 1.6 nM and 62 nM, respectively. |
| M21626 | Cadisegliatin (TTP-399) | Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes. |
| M21625 | CAM833 | CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. |
| M21624 | Timentin (Ticarcillin/Clavunate, 15:1) | |
| M21623 | Clavulanate Potassium | Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic. |
| M21622 | Bepirovirsen | Bepirovirsen is an antisense oligonucleotide targeting all HBV messenger RNAs. Bepirovirsen leads to reductions in HBV-derived RNAs, HBV DNA and viral proteins. |
| M21621 | Recombinant Rat GM-CSF Protein (CHO) | Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. ED50 < 5.0 pg/ml, measured in a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of > 2.0 × 108 units/mg. |
| M21620 | WYRGRL | WYRGRL is a collagen type II-binding peptide. The WYRGRL peptide has an inherent affinity for the cartilage matrix component of collagen II protein. |
| M21619 | Recombinant Human SCARB2 (Mammalian, C-6His) | Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Recombinant Human Scavenger Receptor Class B Member 2 is produced by Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a 6His tag at the C-terminus. |
| M21618 | Violacein | Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities. |
| M21617 | Recombinant Human NANS (E.coli, N-6His) | N-Acetylneuraminate Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. Recombinant Human N-Acetylneuraminate Synthase is produced by E.coli expression system and the target gene encoding Met1-Ser359 is expressed with a 6His tag at the N-terminus. |
| M21616 | Cytidine-5'-monophospho-N-acetylneuraminic acid | Cytidine-5'-monophospho-N-acetylneuraminic acid is a nucleotide. |
| M21615 | MitoTEMPOL | MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. |
| M21614 | 2'3'-cGAMP | 2'3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm. |
| M21613 | Recombinant Human UBE2V1 (E.coli, C-6His) | Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. |
| M21612 | Recombinant Mouse IFN-beta Protein (HEK293) | Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relapsing-remitting multiple sclerosis. Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 3-18 pg/mL. |
| M21611 | Peptidoglycan | The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell wall of most bacteria. |
| M21610 | Recombinant Mouse IL-7 (CHO, His) | Recombinant Mouse IL-7 (Interleukin-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. ED50 is < 0.4 ng/ml, measured in a cell proliferation assay using 2E8 cells. |
| M21609 | Recombinant Mouse Adiponectin (E. coli) | Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. Measured by a cell growth inhibitory assay using M1 cells, the ED50 is < 5.0 µg/ml, corresponding to a specific activity of > 2.0 × 102 units/mg. |
| M21608 | L-Phenylalanyl-L-leucine | L-Phenylalanyl-L-leucine is a leucine derivative. |
| M21601 | Pamoic acid | Pamoic acid is a potent GPR35 agonist with EC50 at 79 nM. Pamoic acid has neuroprotective and anti-inflammatory properties. |
| M21600 | Plitidepsin | Plitidepsin (Aplidine) is a potent anticancer compound targeting eEF1A2 (KD=80 nM). Plitidepsin has antiviral activity, and the IC90 of inhibiting SARS-CoV-2 is 0.88 nM. Plitidepsin is commonly used in multiple myeloma and advanced cancer research and has potential for COVID-19 research. |
| M21599 | Dextran-500kd | Dextran-500kd (Glucan 500) is a multipurpose branched glucan, which can improve plasma colloid osmotic pressure, increase blood volume, reduce platelet adhesion, inhibit red blood cell aggregation, reduce blood viscosity, reduce peripheral circulation resistance, and unclog microcirculation. |
| M21598 | Nicotinic acid mononucleotide | In the biosynthesis of NAD+, Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) by nicotinic phosphate ribosyltransferase. Nicotinate mononucleotide is the substrate of nicotinamide mononucleotide/nicotinic acid mononucleotide adenylyl transferase. |
| M21597 | Beauvericin | Beauvericin is a fusarium toxin. It has a wide range of antifungal, antibacterial, protozoal and insecticidal activities, exhibits ionic properties and inhibits acyl-coenzyme: cholesterol acyltransferase activity; Apoptosis was induced by increasing intracellular calcium levels. |
| M21596 | Pseudouridine | Pseudouridine, an isomer of uridine, is also the most abundant modified nucleoside in non-coding RNA. Pseudouridine can fine-tune and stabilize the regional structure in rRNA and tRNA to maintain their function in mRNA decoding, ribosome assembly, processing, and translation. |
| M21595 | Psammaplin A | Psammaplin A is a Marine metabolite that acts as a potent inhibitor of HDAC and DNA methyltransferases. Psammaplin A is a highly selective HDAC1 inhibitor with an IC50 of 0.9 nM, which is 360 times more selective to HDAC1 than DAC6 and more than 1000 times less potent to HDAC7 and HDAC8. |
| M21594 | Aeroplysinin 1 | Aeroplysinin 1 is a metabolite isolated from sponge V. aerophoba and has anti-inflammatory, antiangiogenic and antitumor activities. It's a tertiary alcohol. Aeroplysinin 1 induced endothelial cell Apoptosis. |
| M21593 | Aaptamine | Aaptamine, an alkaloid isolated from sponge Aaptos aaptos in the ocean, is a competitive antagonist of alpha-adrenergic receptors to activate the p21 promoter independently of the p53 pathway. |
| M21592 | Didemnin B | Didemnin B is a cyclic separation peptide isolated from trididemum solidum extract. It has antiviral and antitumor effects. |
| M21591 | RLX-33 | RLX-33 is a potent and selective blood-brain barrier permeable relaxin family peptide 3 (RXFP3) antagonist that also blocks relaxin 3 (Relaxin 3) -induced ERK1/2 phosphorylation. The IC50 phosphorylated RXFP3, ERK1 and ERK2 were 2.36μM, 7.82μM and 13.86μM, respectively. RLX-33 can block the increase of food intake in rats induced by RXFP3 selective agonist R3/I5. RLX-33 can be used in the study of metabolic syndrome. |
| M21590 | Vornorexant | Vornorexant (ORN-0829; TS-142) is an effective dual antagonist of OX1R and OX2R, with IC50 values of 1.05 nM and 1.27 nM, respectively. Vornorexant has shown effective sleep promotion in animal models and can be used to study insomnia. |
| M21589 | OM-153 | OM-153 is a potent, orally active tankyrase inhibitor with IC50 of 13 nM for tankyrase 1 and 2 nM for tankyrase 2 (TNKS1/2). OM-153 inhibited luciferase based Wnt/β-catenin signal transduction reporter activity with IC50 of 0.63 nM. OM-153 inhibits Wnt/β-catenin signal transduction and proliferation in COLO 320DM. |
| M21588 | GSK2646264 | GSK2646264 is a potent and selective splenic tyrosine kinase (Syk) inhibitor with a pIC50 value of 7.1. GSK2646264 also inhibited other kinases, with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, <4.6 and <4.3 for LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B and Aurora A, respectively. GSK2646264 penetrates into the epidermis and dermis of the skin. |
| M21587 | OBI-3424 | OBI-3424 is a highly selective precursor compound that can be converted into an effective dna alkylating agent by AKR1C3(aldokeone reductase 1C3). It can be used in studies of hepatocellular carcinoma, castration-resistant prostate cancer and acute lymphoblastic leukemia (ALL). |
| M21586 | Poly(2-hydroxyethyl methacrylate) (MW 1000000) | Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials field. Poly(2-hydroxyethyl methacrylate) serves as the basic component of contact lenses, and is also used for soft tissue implantation, synthetic transplantation of carwrist and bone, regeneration of nervous system tissues, compound delivery, etc. |
| M21585 | Poly(2-hydroxyethyl methacrylate) (MW 20000) | Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials field. Poly(2-hydroxyethyl methacrylate) serves as the basic component of contact lenses, and is also used for soft tissue implantation, synthetic transplantation of carwrist and bone, regeneration of nervous system tissues, compound delivery, etc. |
| M21584 | Protamine sulfate | Protamine sulfate is a positive ionic peptide with anti-heparin activity. Protamine sulfate has strong alkaline groups, which combine with strongly acidic heparin in the body to form a stable compound, making heparin lose its anticoagulant ability. |
| M21583 | Tofersen | Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce SOD1 protein synthesis. Tofersen can be used in amyotrophic lateral sclerosis (ALS) research. |
| M21582 | L-Glucose | L-glucose (L-(-) -glucose) is an enantiomer of D-glucose. L-Glucose enhances food intake, and cells can't use it as an energy source because it can't be phosphorylated by hexokinase. |
| M21581 | Magnesium sulfate | Magnesium sulfate is a type of inorganic salt. Magnesium sulfate is currently the preferred anticonvulsant compound for preventing and controlling the onset of eclampsia. Magnesium sulfate is also widely used as a contraction agent. |
| M21580 | EG-011 | WASp is a new target for hematological cancers. The Westcott-Aldridge syndrome protein (WASp) is a protein expressed almost exclusively in hematopoietic cells that promotes actin polymerization. |
| M21579 | TDI-11861 | sAC inhibitors such as DI-11861 can be used effectively as a compound for on-demand, non-hormonal male contraception. |
| M21578 | ENT-01 | ENT-01 is an antibiotic. |
| M21577 | Sirpiglenastat | Sirpiglenastat (DRP-104) is a broad acting glutamine (glutamine) antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing an effective antitumor immune response. |
| M21576 | PTC258 | PTC258 is an oral, brain-penetrating splicing modulator targeting ELP1. |
| M21575 | ervogastat | ervogastat is a similar DGAT2 inhibitor used to treat NASH. Hepatic triglyceride (TG) accumulation is a symptom of non-alcoholic fatty liver disease (NAFLD) that can progress to non-alcoholic steatohepatitis (NASH), which is characterized by liver cell damage, inflammation, and collagen deposition (fibrosis). |
| M21574 | TAM&Met-IN-1 | TAM&Met-IN-1 is a potent TAM and c-Met inhibitor with IC50 of 6.1 nM, 13.2 nM and 21.6 nM against AXL, MER and TYRO3, respectively. TAM&Met-IN-1 can be used in anticancer research. |
| M21573 | Recombinant Human/Cynomolgus CD28 (Mammalian, N-6His) | Recombinant human t cell specific surface glycoprotein CD28 is produced by mammalian expression systems, and the target gene encoding Asn19-Pro152 is expressed in the N-terminal with the 6His tag. Protein number: P10747. |
| M21572 | Recombinant Human CD3E (Mammalian, C-Fc) | Recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression system, and the target gene encoding Asp23-Asp126 is expressed in the C-terminal human IgG1 Fc tag. Protein number: P07766. |
| M21571 | Recombinant Human CD3E (Mammalian, C-mFc) | The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Gln22-Thr48 is expressed at the C-terminal using mouse IgG1 Fc tag. Protein number: P07766. |
| M21570 | Recombinant Human CD3E (Mammalian, C-6His) | The recombinant human t cell surface glycoprotein CD3 Epsilon chain is produced by mammalian expression systems, and the target gene encoding Asp23-Asp126 is expressed by 6His tag at the C-terminal. Protein number: P07766. |
| M21569 | Diethyl succinate | Diethyl succinate (Diethyl Butanedioate) is the Diethyl form of succinate. Diethyl succinate (Diethyl Butanedioate) can be used at physiological pH and passed through a biofilm. Incorporated into cells in tissue cultures and metabolized through the TCA cycle. Diethyl succinate was not toxic. |
| M21568 | Apostatin-1 | Apostatin-1 (Apt-1) is a new type of TRADD inhibitor. Apostatin 1 can bind to TRADD-N (KD=2.17 μM), and destroy the binding of Apostatin 1 to TRADD-C and TRAF2. Apostatin-1 regulates ubiquitination of RIPK1 and beclin 1. By activating autophagy in cells accumulated by mutated tau, α-synuclein or huntingtin, Apostatin 1 blocked apoptosis and restored homeostasis. |
| M21567 | Necrostatin-34 | Necrostatin 34 (Nec-34) is an inhibitor of RIPK1 kinase that stabilizes RIPK1 in a deactivated state by occupying specific binding pockets in the kinase domain. |
| M21566 | RIPK1-IN-4 | RIPK1-IN-4 is a potent type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to the inactive form of RIP1 in D1-out. For RIP1 and ADP-Glo kinases, IC50 was 16 nM and 10 nM, respectively. |
| M21565 | RIPK1-IN-10 | Ripk1-in-10 is a potent inhibitor of RIPK1. |
| M21564 | RIPK1-IN-7 | Ripk1-in-7 is a receptor interacting protein kinase 1 (RIPK1) inhibitor with Kd value of 4 nM and IC50 value of 11 nM. RIPK1-IN-7 showed good antimetastatic activity in experimental B16 melanoma lung metastasis model. |
| M21563 | Ethoxylated hydrogenated castor oil | Ethoxylated castor oil (PEG-40 hydrogenated castor oil) is a mixture of polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used for emulsification and solubility of oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a co-solvent for animal experiments. |
| M21562 | Zymosan A from Saccharomyces cerevisiae | Zymosan A can increase the level of cyclin D2, suggesting the role of cyclin D2 in macrophage activation and proliferation. After injection of galactosamine, it aggravated acute liver injury, suggesting that some non-parenchymal cells besides Kupfer's cells were involved in fermentase action. |
| M21561 | Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride | Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescence indicator widely used as a probe for luminescence detection and oxygen quantification. The maximum absorption wavelength is max 455 nm and the maximum luminescence is λmax 613 nm. |
| M21560 | Racanisodamine | Racanisodamine (7 beta Hydroxyhyoscyamine) is a racemic substance with similar pharmacological effects. Racanisodamine is a vasoactive Chinese herbal extract used to study acute disseminated intravascular coagulation in patients with bacterial shock. |
| M21559 | ART615 | ART615 is a related isomer of ART558. ART615 is an inactive form of ART558, causing <10% Polθ inhibition at 12 μM, so it can be used as a control for ART558 (IC50=7.9 nM). |
| M21558 | ART812 | ART812 is an orally effective DNA polymerase Polθ inhibitor with an IC50 value of 7.6 nM. ART812 had an IC50 value of 240 nM for cell-based microhomologous mediated end-junction (MMEJ). |
| M21557 | RP-6685 | RP-6685 is a potent, selective and orally active inhibitor of DNA polymerase θ (Polθ) with an IC50 value of 5.8 nM (PicoGreen assay). RP-6685 showed antitumor effect in mouse tumor transplantation model. |
| M21556 | Recombinant Human IL-17A（E.coli) | Recombinant human interleukin 17a is produced by the Escherichia coli expression system and expresses the target gene encoding Gly24-Ala155. Protein number: Q16552. |
| M21555 | Recombinant Mouse PDGF-AA （E. coli） | Platelet-derived growth factor-AA (PDGF-AA) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed from four different PDGF subunits. Accession # P20033. |
| M21554 | Recombinant Human FGF-4（E. coli) | Fibroblast growth factor-4 (FGF-4), also known as K-FGF, is a heparin-bound growth factor in the FGF family. It is identified by its carcinogenic transforming activity. Accession # P08620. |
| M21553 | Poly-L-lysine(MW4000～15000） | Poly-L-lysine |
| M21552 | FeRhoNox-1 (Fe2+ indicator) | FeRhoNox-1, also known as RhoNox-1, is an active fluorescent probe that specifically detects unstable iron (1) ions (Fe2+). After the reaction of -denier with Fe2+, -orange (red) fluorescent products are irreversibly generated. (Absmax= 540nm, FLmax= 575nm). |
| M21551 | Cyclo[Arg-Gly-Asp-D-Phe-Lys(Cys)] | Cyclo[Arg-Gly-Asp-D-Phe-Lys(Cys)] is a peptide that binds to integrins, a type of receptor protein on the surface of cells. |
| M21550 | Recombinant Mouse/Rat TGF-beta 1（Mammalian） | Recombinant mouse/rat transforming growth factor β1 is produced by the mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. Protein number :P04202. |
| M21549 | Recombinant Human IFN-α 1b（E. coli） | Protein structure: represented by n-terminal Met. Accession # P01562. Compared with the standard, it has complete biological activity. The specific activity determined by antiviral test was not less than 1.0 × 10 8IU/mg. |
| M21548 | CMFDA | CMFDA is a cell-permeable fluorescent probe that can be used as a cellular tracer. CMFDA can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope. |
| M21547 | Recombinant Mouse PCSK9 (Mammalian, C-6His) | Recombinant mouse Proprotein Convertase Subtilisin/Kexin Type 9 was produced by the mammalian expression system, and the target genes encoding gln35-gln155 and ser156-gln694 were expressed by 6His tag at the C-terminal. Protein number: Q80W65. |
| M21546 | Recombinant Mouse IL-3 (E. coli, C-6His) | Interleukin-3 (IL-3) is a multipotent cytokine belonging to the interleukin-family. Biological activity: ED50 < 0.05 ng/ml was determined by M-NFS-60 cell proliferation method, and the corresponding specific activity was 2.0 × 10 7 units /mg. |
| M21545 | 4-Phenoxyphenylboronic acid | 4-phenoxy phenylboric acid can be used as a reactant. |
| M21544 | 4-Biphenylboronic acid | 4-Biphenylboronic acid is a boric acid compound. |
| M21543 | N-(2-Cyanoethyl)glycine | N-(2-Cyanoethyl)glycine is a glycine derivative. |
| M21542 | Deoxyribonucleic acid sodium salt from salmon testes | Salmon refined deoxyribonucleic acid (SS-DNA) can be used to study the physical and chemical interactions of DNA with binders, inserters, modifiers, detection agents and densifiers. Salmon extract DNA was used to investigate the loading capacity of magnetic mesoporous silica nanoparticles (M-MSNs) and the bonding capacity of polymer nanolayer structures. SS-DNA can be used as a substrate for developing DNA detection methods. |
| M21541 | L-2-Aminooxy-3-phenylpropanoic acid | L-2-Aminooxy-3-phenylpropanoic acid is an inhibitor of L-phenylalanine ammonia-lyase. |
| M21540 | L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) | L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) is a long-term vitamin C derivative that can stimulate the expression and formation of collagen. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) can be used as a medium to supplement osteogenic differentiation of human adipose stem cells (hASCs). Increased alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation. |
| M21539 | TC LPA5 4 | TC LPA5 4 is a specific non-lipid LPA5 (GPR92) antagonist (IC50=0.8 μM in LPA5-RH7777 cells). Shows selectivity for LPA5 against 80 other screening targets.TC LPA5 4 was shown to inhibit LPA-induced aggregation of isolated human platelets.TC LPA5 4 inhibits proliferation and migration of thyroid cancer cells. |
| M21538 | Diphenyl diselenide | Diphenyl diselenide inhibits δ-aminolevulinic acid dehydrase (δ-ALA-D) in brain, liver, and kidney in vivo. Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction. |
| M21537 | Urokinase | Urokinase (urokinase) is a proteolytic enzyme. It can be used as a highly effective thrombolytic agent and also has a local vasodilating effect. Used as an antithrombotic compound. |
| M21536 | BAY-069 | BAY-069 is a branched-chain amino acid transaminase (BCAT) 1/2 inhibitor. Involved in the synthesis and catabolism of branched-chain amino acids. |
| M21535 | UCB7362 | UCB7362 is an oral plasma protease X (PMX) inhibitor that is being developed as an anti-malarial compound. |
| M21534 | AN15368 | AN15368 is an oral cleavage and polyadenylate specific factor (CPSF3) inhibitor being developed for use in Chagas disease (also known as American trypanosomiasis). |
| M21533 | BI-0474 | BI-0474 is a covalent KRASG12C inhibitor. The IC50 value for GDP-KRAS::SOS1 protein-protein interaction was 7.0 nM. BI-0474 also showed better antitumor activity in non-small cell lung cancer xenograft models. |
| M21532 | JNJ-64264681 | JNJ-64264681 is a covalent Bruton tyrosine kinase (BTK) inhibitor under development for hematological malignancies. |
| M21531 | GDC-2394 | GDC-2394 is an oral inhibitor of NLRP3 inflammasome. The NLRP3 inflamome, the best studied and most characterized, also inhibits IL-1β with IC50 of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). |
| M21530 | Sebetralstat | Sebetralstat is an oral, on-demand plasma adrenalin trophin (PKa) inhibitor for hereditary angioedema (HAE). It can be used in the study of acute attacks. |
| M21529 | All-trans-retinal | All-trans-retinal is one of the major vitamin A metabolites in the retina. It is converted into retinoic acid in the body by retinal dehydrogenase. It is an effective photosensitizer.*The compound is unstable in solutions, freshly prepared is recommended |
| M21528 | 1-Carbamoylcyclopropanecarboxylic acid | |
| M21527 | MES hydrate | MES is a buffer solution. MES is an amphoteric ion N- substituted sulfamic acid with a morpholine ring. This composition does not form complexes with most metals used in environmental and biological research. It is soluble in water but extremely insoluble in lipids, and therefore unable to penetrate membranes. |
| M21526 | Recombinant Human S100A11（E.coli ） | The recombinant human protein S100-A11 was produced by the expression system of Escoli and the target gene Met1-Thr105 was expressed. Protein number: P31949. |
| M21525 | Recombinant Mouse S100A11 (E.coli , N-6His) | The recombinant mouse protein S100-A11 was produced by the Escoli expression system, and the target gene Met1-Ile98 was expressed with 6His marker at the n terminal. Protein number: P50543. |
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