Cat.No. | Name | Information |
---|---|---|
M22487 | RBN-3143 | RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. |
M22486 | AH-7614 | AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). |
M22485 | Recombinant Human CD14 (Mammalian, C-6His) | Recombinant Human CD14 is produced by Mammalian expression system and the target gene encoding Thr20-Cys352 is expressed with a 6His tag at the C-terminus. CD14 is a cell surface glycoprotein that is preferentially expressed on monocytes/macrophages. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a pattern recognition receptor that binds lipopolysaccharides (LPS) and a variety of ligands derived from different microbial sources. |
M22484 | Mito Red | Mito Red is a cell membrane permeable rhodamine based dye. It localizes mitochondria, and emits red fluorescence. λex 569 nm; λem 594 nm in DMSO |
M22483 | Linvencorvir (RG7907) | Linvencorvir (RG7907) is a hepatitis B virus (HBV) core protein allosteric modulator, it is an antiviral agent. |
M22482 | Recombinant Murine GM-CSF Protein (HEK293, C-His) | Recombinant Murine GM-CSF Protein is a hematopoietic growth factor that can promote the development of neutrophils and macrophages, and promote the proliferation and development of early erythroid megakaryocytes and eosinophilic progenitors. |
M22481 | L-Ribulose | L-Ribulose is an important precursor for other rare sugars and L-nucleoside analogue synthesis. |
M22480 | 8-Bromo-cGMP sodium | 8-Bromo-cGMP sodium is a PKG (protein kinase G) activator, it is a membrane-permeable analogue of cGMP. 8-Bromo-cGMP sodium significantly inhibits Ca2+ macroscopic currents and impairs insulin release stimulated with high K+. |
M22479 | Lisaftoclax | Lisaftoclax (APG-2575) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. |
M22478 | Zilurgisertib | Zilurgisertib is a selective ALK2 inhibitor. |
M22477 | Recombinant Human FSH (Mammalian, C-Flag&6His) | Recombinant Human Follicle-Stimulating Hormone (FSH) is produced by Mammalian expression system and the target gene encoding Ala25-Ser116&Asn19-Glu129 is expressed with a Flag tag&6His at the C-terminus. FSH is a member of glycoprotein hormones subunit beta family, whichalso includes LH, CG and TSH. |
M22476 | Exarafenib | Exarafenib (KIN-2787) is a highly selective, potent, next-generation, pan-RAF inhibitor with activity across BRAF and RAS mutant human tumor cell models. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. |
M22475 | Insulin glargine | Insulin glargine is a long-acting insulin analog. Insulin glargine can be used for the research of diabetes mellitus. |
M22474 | Insulin aspart | Insulin aspart (B28Asp) is a fast-acting analog of human insulin. Insulin aspart can be used for researching diabetes. |
M22473 | Insulin lispro | Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus. |
M22472 | Insulin degludec | Insulin degludec is an ultra-long-acting form of insulin, shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes. |
M22471 | Rafutrombopag | Rafutrombopag is a thrombopoietin (TPO) agonist. |
M22470 | TA-316 | TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells. |
M22469 | G3-C12 | G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. |
M22468 | Sovilnesib (AMG 650) | Sovilnesib (AMG 650) is a potent, orally active kinesin-like protein KIF18A inhibitor with an IC50 value of 0.071 μM. |
M22467 | Danvatirsen | Danvatirsen is an antisense oligonucleotide targeting STAT3 with potential antitumor activity. Danvatirsen binds to STAT3 mRNA, thereby inhibiting translation of the transcript. |
M22466 | Emraclidine (CVL-231) | Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator. Emraclidine can be used for the research of neurological diseases. |
M22465 | Tyclopyrazoflor | Tyclopyrazoflor is an anthranilamide compound with pesticidal activity. |
M22464 | M4205 | M4205 is a c-KIT inhibitor, with an IC50 of 10 nM for c-KIT V654A. M4205 has high activity on c-KIT mutations in exon 11, 13, 17. |
M22463 | Recombinant Human UBA1 Protein (Baculovirus-Insect, His & GST Tag) | The recombinant human UBA1/GST chimera consists of 1294 amino acids and has a calculated molecular mass of 146 KDa. A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
M22462 | Recombinant Human UBE2D1 (E.coli, N-GST) | Recombinant Human UBE2D1 is produced by E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus. Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. |
M22461 | 1-Boc-3-AMino-4-fluoropyrrolidine | 1-Boc-3-AMino-4-fluoropyrrolidine |
M22460 | UDP-glucuronic acid trisodium | UDP-glucuronic acid (UDPGA) trisodium is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids. |
M22459 | Recombinant Human EGF Protein (HEK293, hFc) | EGF is the founding member of the EGF-family of proteins. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblast cells, the ED50 for this effect is typically 0.3-1.5 ng/mL. |
M22458 | Recombinant Rat CXCL2/CINC-2 Protein (E. coli) | CXCL2/CINC-2, also called macrophage inflammatory protein 2 (MIP-2), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2), is a small cytokine belonging to the CXC chemokine family. CXCL2/MIP-2 is selectively up-regulated in tolerance-conferring APCs and serves to recruit NKT cells to the splenic marginal zone, where they form clusters with APCs and T cells. |
M22457 | Recombinant Rat CXCL1/CINC-1 Protein (E. coli) | Rat CXCL1, also known as CINC-1, is belonging to the CXC chemokine family. CXCL1 may act as a chemoattractant for osteoclast precursors. CXCL1 may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. |
M22456 | Recombinant ASFV p72 complex | Recombinant ASFV p72 complex is produced by Mammalian expression system and the target gene encoding Met1-Thr646&Met1-Leu530 is expressed with a 10His-3*Flag tag and a Flag-Strep tag at the N-terminus. Protein p72 is the major capsid protein of African swine fever virus (ASFV) and is an important target for test and vaccine development. |
M22455 | PLGA lactide:glycolide (50:50) MW 120000 | Poly(D,L-lactide-co-glycolide) is a synthetic amino acid that has been used to deliver macromolecular therapeutics. |
M22454 | Recombinant Human STC-1 (Mammalian, C-6His) | Recombinant Human Stanniocalcin 1/STC-1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. |
M22453 | BMF-219 | BMF-219 is a specific irreversible inhibitor of Menin-MLL interactions, and it can be used in the study of autoimmune diseases, alloimmune diseases, cancer and other diseases dependent on menin-MLL. |
M22452 | 2'-C-Methyladenosine | 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication, it inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3 μM and 1.9 μM, respectively. |
M22451 | Recombinant Human ApoE (Mammalian, C-6His) | Recombinant Human Apolipoprotein E is produced by Mammalian expression system and the target gene encoding Lys19-His317 is expressed with a 6His tag at the C-terminus. ApoE is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons. ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma. |
M22450 | Recombinant Human AMH Protein (HEK293, His Tag) | Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. |
M22449 | Pomalidomide-PEG2-COOH | Pomalidomide-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. |
M22448 | Thalidomide-NH-PEG3-propionic acid | Thalidomide-NH-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. |
M22447 | Glycerol tristearate | Glycerol tristearate |
M22446 | Ferrous Bisglycinate | Ferrous Bisglycinate |
M22445 | Fosamprenavir | Fosamprenavir |
M22444 | Flupirtine | Flupirtine |
M22443 | Fluopyram | Fluopyram |
M22442 | Flavin Adenine Dinucleotide | Flavin Adenine Dinucleotide |
M22441 | Formoterol | Formoterol |
M22440 | ETH 4030 | ETH 4030 |
M22439 | Enocyanin | Enocyanin |
M22438 | Efloxate | Efloxate |
M22437 | Eravacycline dihydrochloride | Eravacycline dihydrochloride |
M22436 | Elubiol | Elubiol |
M22435 | DLin-KC2-DMA | DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6), produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). |
M22434 | 16-Dehydropregnenolone | 16-Dehydropregnenolone |
M22433 | DL-Histidine | DL-Histidine |
M22432 | D-Histidine | D-Histidine |
M22431 | D-Homoproline | D-Homoproline |
M22430 | D-Cysteine hydrochloride monohydrate | D-Cysteine hydrochloride monohydrate |
M22429 | D-Cellobiose octaacetate | D-Cellobiose octaacetate |
M22428 | D-Cystine | D-Cystine |
M22427 | DL-Cystine | DL-Cystine |
M22426 | Cefamandole sodium | Cefamandole sodium |
M22425 | Cetirizine | Cetirizine |
M22424 | Cyproconazole | Cyproconazole |
M22423 | Calcium DL-malate | Calcium DL-malate |
M22422 | Caramel | Caramel |
M22421 | Cryptocyanine | Cryptocyanine |
M22420 | Croton Oil | Croton Oil |
M22419 | Cocamidopropyl betaine | Cocamidopropyl betaine |
M22418 | Calcium phosphorylcholine chloride | Calcium phosphorylcholine chloride |
M22417 | Bazedoxifene | Bazedoxifene |
M22416 | Bicyclomycin benzoate | Bicyclomycin benzoate |
M22415 | Bromobimane | Bromobimane |
M22414 | Buserelin Acetate | Buserelin Acetate |
M22413 | Allopurinol riboside | Allopurinol riboside |
M22412 | Azelastine | Azelastine |
M22411 | AG1406 | AG1406 |
M22410 | ADX88178 | ADX88178 |
M22409 | Amikacin | Amikacin |
M22408 | 8-Azaadenine | 8-Azaadenine |
M22407 | Azure II | Azure II |
M22406 | Glucan | Glucan |
M22405 | Glycine benzyl ester p-toluenesulfonate salt | Glycine benzyl ester p-toluenesulfonate salt |
M22404 | Glycine ethyl ester hydrochloride | Glycine ethyl ester hydrochloride |
M22403 | Glycine methyl ester hydrochloride | Glycine methyl ester hydrochloride |
M22402 | Fostriecin sodium salt | Fostriecin sodium salt |
M22401 | F-Amidine trifluoroacetate salt | F-Amidine trifluoroacetate salt |
M22400 | Furegrelate sodium salt | Furegrelate sodium salt |
M22399 | FLT3 Inhibitor III | FLT3 Inhibitor III |
M22398 | Finafloxacin hydrochloride | Finafloxacin hydrochloride |
M22397 | Fiduxosin | Fiduxosin |
M22396 | Fusicoccin | Fusicoccin |
M22395 | FUBIMINA | FUBIMINA |
M22394 | 5-Fluoropentylindole | 5-Fluoropentylindole |
M22393 | FR 139317 | FR 139317 |
M22392 | Fumonisin B3 | Fumonisin B3 |
M22391 | FK1052 hydrochloride | FK1052 hydrochloride |
M22390 | Fluorocyclopentenylcytosine | Fluorocyclopentenylcytosine |
M22389 | c-Fms inhibitor 2 | c-Fms inhibitor 2 |
M22388 | Flurofamide | Flurofamide |
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