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Ozuriftamab vedotin (BA3021) is an antibody-drug conjugate (ADC), it is composed of receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab and VcMMAE.
Immobilized ROR2 at 2 μg/mL (30 uL/well) can bind ozuriftamab vedotin, the EC50 is 0.160 ug/mL.
Human ROR2 CHO-S Cell Line were stained with ozuriftamab vedotin and negative control protein respectively, washed and then followed by PE and analyzed with FACS, the EC50 is 0.2650 μg/mL.
The drug-to-antibody ratio (DAR) of the ozuriftamab vedotin is 3.9.
| CAS Number | 2460400-11-5 |
| Storage | Store at ≤ -20℃ for 24 months. Avoid repeated freeze-thaw cycles. |
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