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Cytokines and Growth Factors Cytokines and Growth Factors

Cat.No.  Name Information
M22482 Recombinant Murine GM-CSF Protein (HEK293, C-His) Recombinant Murine GM-CSF Protein is a hematopoietic growth factor that can promote the development of neutrophils and macrophages, and promote the proliferation and development of early erythroid megakaryocytes and eosinophilic progenitors.
M21466 Recombinant Rat TNF-α (P. pastoris) Recombinant rat tumor necrosis factor produced in Pichia pastoris. TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. ED50 < 50.0 pg/ml
M21094 Recombinant Rat IL-1β (E. coli) Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg.
M19999 Recombinant Mouse IL-2 (E.coli) Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml
M10465 Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression.
M10022 Recombinant Mouse GM-CSF Protein (CHO) Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg.
M9987 Recombinant Human PDGF-AA Protein (HEK293) Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.
M9981 Recombinant Human IL-11 Protein (E. coli) Recombinant Human IL-11 Protein is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability.
M9406 Recombinant Human bFGF Protein (HEK293) Recombinant Human bFGF Protein (HEK293)
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) Recombinant Human PDGF-BB Protein (HEK293)
M9391 Recombinant Human TGF-β1 (CHO) Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis.
M9370 Recombinant Human TNF α (HEK293, C-His) Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections.
M9241 Recombinant Human EPO Protein (CHO) Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells.
M58627 Recombinant Human FGF-8b Protein (E. coli) Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect.
M58618 Recombinant Rat GDNF Protein (Baculovirus-Insect, N-His) GDNF is an important member of the GDNF family of ligands. GDNF plays a key role in the promotion of the survival of dopaminergic neurons. GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein also promotes the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. GDNF also regulates kidney development and spermatogenesis, and it affects alcohol consumption.
M58602 Recombinant Rat PDGF-BB (E. coli) Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic.
M58600 Recombinant Human ApoE3 Protein (HEK293, C-6His) ApoE is a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport. ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma.
M58590 Recombinant Mouse Granzyme B (HEK293, C-6His) Granzyme B (GZMB) is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.




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