| Cat.No. | Name | Information |
|---|---|---|
| M21466 | Recombinant Rat TNF-α (P. pastoris) | Recombinant rat tumor necrosis factor produced in Pichia pastoris. TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. ED50 < 50.0 pg/ml |
| M21094 | Recombinant Rat IL-1β (E. coli) | Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg. |
| M19999 | Recombinant Mouse IL-2 (E.coli) | Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells. |
| M10922 | Recombinant Mouse TGF-beta 1 Protein (Human Cells) | Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml |
| M10465 | Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) | Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. |
| M10022 | Recombinant Mouse GM-CSF Protein (CHO) | Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg. |
| M9987 | Recombinant Human PDGF-AA Protein (HEK293) | Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. |
| M9981 | Recombinant Human IL-11 Protein (HEK293) | Recombinant Human IL-11 Protein (HEK293) is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. |
| M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. |
| M9406 | Recombinant Human bFGF Protein (HEK293) | Recombinant Human bFGF Protein (HEK293) |
| M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | Recombinant Human PDGF-BB Protein (HEK293) |
| M9391 | Recombinant Human TGF-β1 (HEK293, C-Fc) | Recombinant Human TGF-β1 (HEK293) regulates cell proliferation, growth, differentiation and cells movement. The ED50 is ≤ 0.5 ng/mL as measured by HT-2 cells. |
| M9370 | Recombinant Human TNF α (HEK293, C-His) | Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections. |
| M9241 | Recombinant Human EPO Protein (HEK293, C-His) | Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
| M55397 | Recombinant Human HMGB1 Protein (E. coli) | High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
| M55382 | Recombinant Human IL-25/IL-17E (E. coli, C-His) | Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| M55381 | Recombinant Human IL-25/IL-17E (Mammalian, C-6His) | Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. |
| M55380 | Recombinant Human SEMA3A (Mammalian, N-6His-Flag) | Semaphorin 3A (SEMA3A) is a secreted protein which belongs to the semaphorin family. Semaphorin 3A can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. |
| M55375 | Recombinant Human CD143/ACE (E. coli, N-GST) | CD143/ACE Protein is a recombinant human Angiotensin I-converting enzyme (ACE, CD143) which hydrolyzes small peptides such as angiotensin I, bradykinin, substance P, LH-RH and several others and thus plays a key role in blood pressure regulation and vascular remodeling. ACE plays a crucial role in blood pressure regulation, vascular remodeling, and immunity. |
| M55374 | Recombinant Human Neprilysin (Mammalian, N-8His) | Neprilysin/CD10 (MME; NEP) is a zinc metallopeptidase expressed at the cell surface of a variety of cells. Neprilysin/CD10 (MME) has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide. |
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