Free shipping on all orders over $ 500

Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed)

Cat. No. M10465
Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed) Structure
Synonym:

rMuIL-4

Size Price Availability Quantity
10ug USD 200  USD200 In stock
50ug USD 600  USD600 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. It is produced by mast cells, activated T cells and bone marrow stromal cells. IL-4 regulates the differentiation of native CD4+ T cells (Th0 cells) into helper Th2 cells, and regulates the immunoglobulin class switching to the IgG1 and IgE isotypes. IL-4 also plays a major role in inflammation response and wound repair via activation of macrophage into M2 cells.

ED50 < 2 ng/ml, measured in a cell proliferation assay using murine HT-2 cells, corresponding to a specific activity of >5 x 105 units/mg.

Accession: # P07750

Apparent Molecular Weight: ~15 kDa, on SDS-PAGE under reducing conditions.

Lyophilized after extensive dialysis against PBS.

Product Citations
Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml.
Storage Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added.
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related Recombinant Proteins Products
Recombinant Mouse GDF15 (Mammalian, N-8His-Flag)

Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development.

Recombinant Mouse CX3CL1 Protein (Mammalian, C-6His)

C-X3-C motif Chemokine 1 (CX3CL1; Fractalkine) is a single-pass type I membrane protein which belongs to the intercrine delta family. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.

Recombinant Human IL-29/IFN-λ1 (Mammalian, C-10His)

Interleukin-29 (IL-29; IFN-λ1) is a cytokine with immunomodulatory activity. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity.

Recombinant Mouse Decorin Protein (Mammalian, C-6His)

Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.

Recombinant Human Decorin Protein (HEK293)

Decorin (DCN) is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors such as FGF2, GDF8/Myostatin, TGFβ and WISP1. It also binds and activates EGFR, ErbB4 and IGFI-R.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Mouse Interleukin-4 (IL-4) (CHO-expressed), rMuIL-4 supplier, Recombinant Proteins, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.