Cat.No. | Name | Information |
---|---|---|
M54565 | Recombinant Anti-Mouse PD1 mAb | Recombinant Anti-Mouse PD1 mAb is a recombinant monoclonal antibody against the mouse PD1 protein, with the antibody isoform Mouse lgG1/lambda. the antibody efficiently binds to the mPD1 protein on the cell surface and significantly inhibits tumor growth in a mouse tumor model transplanted with MC38 cells. the antibody is used to detect the presence of the mouse PD1 protein on the cell surface of the cell. the antibody is used to detect the presence of the mouse PD1 protein on the cell surface of the cell. |
M6224 | Etanercept | Etanercept is a dimer fusion protein that binds tumor necrosis factor (TNF) as a TNF inhibitor. Etanercept competitively inhibits the binding of TNF-α and TNF-β to TNF receptors on the cell surface, rendering tumor necrosis factor biologically inactive. |
M6223 | Tocilizumab | Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD. |
M6221 | Pertuzumab | Pertuzumab, a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2 to bind to other members of the HER family, MW: 148 KD. |
M6219 | Rituximab | Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD. |
M6218 | Trastuzumab | Trastuzumab is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2, MW:145.53 KD. |
M6166 | Bevacizumab | Bevacizumab (anti-VEGF, Avastin) is a humanized anti-VEGF monoclonal antibody that is an inhibitor of VEGF. It binds to, and neutralizes, all human-derived VEGF-A isoforms (and biologically active protein hydrolysis fragments).MW:149 KD. |
M6101 | Atezolizumab | Atezolizumab (atezolizumab) is a humanized anti-PD-L1 monoclonal antibody that inhibits PD-L1 signaling with PD-1 and B7-1 and restores tumor-specific T-cell immunity. However, it does not affect the interaction of PD-L2 with PD-1. MW: 145 KD. atezolizumab reacts with murine PD-L1 (for human and non-humanized mice). |
M6100 | Nivolumab | Nivolumab (nabumab) is a fully humanized IgG4 monoclonal antibody against PD-1. It has immune checkpoint inhibitory activity and antitumor activity; MW: 143.597 KD.(for human-derived mice). |
M3835 | Alirocumab | Alirocumab is a humanized IgG1 PCSK9 monoclonal antibody that can be used in the study of hypercholesterolemia. |
M3813 | Avelumab (MSB0010718C) | Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Avelumab recognizes murine PD-L1 |
M1503 | Panitumumab | Panitumumab is a fully human IgG2 monoclonal antibody specific to the epidermal growth factor receptor (EGFR). |
M40939 | Rat IgG2b Isotype Control In vivo | Rat IgG2b Isotype Control In vivo monoclonal antibody (Clone:1-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications. |
M40936 | Anti-Mouse CD4 (Clone GK1.5) In vivo | Anti-Mouse CD4 (Clone GK1.5) antibody recognizes an epitope on Mouse CD4. |
M40935 | Anti-Mouse IFNγ (interferon gamma) (Clone H22) In vivo | Anti-Mouse IFNγ (interferon gamma) (Clone H22) antibody recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. |
M40934 | Anti-Mouse CTLA-4 (Clone 9D9) In vivo | Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes. |
M40918 | Anti-Mouse Ly6G (Clone 1A8) In vivo | Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils. |
M40909 | Anti-Mouse CD8a (Clone 53-6.7) In vivo | Anti-Mouse CD8a (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes. |
M40856 | Anti-Mouse CD4 (Clone YTS191) In vivo | Anti-Mouse CD4 (Clone YTS191) recognizes an epitope on mouse CD4. CD4 is expressed on most thymocytes, MHC class II-restricted T cells, a subset of NKT cells, and subsets of dendritic cells and macrophages. |
M40830 | Anti-Mouse CD3ε In vivo | Anti-Mouse CD3ε (Clone 145-2C11) recognizes an epitope on mouse CD3ε. CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes. |
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