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Panitumumab is a fully human IgG2 monoclonal antibody specific to the epidermal growth factor receptor (EGFR). Panitumumab works by binding to the extracellular domain of the EGFR preventing its activation. This results in halting of the cascade of intracellular signals dependent on this receptor. The pharmacokinetics (PK) of panitumumab shows the so-called target-mediated disposition behavior.
ACS Appl Mater Interfaces. 2023 Jan 26.
Protein Release by Controlled Desorption from Transiently Cationic Nanoparticles
Panitumumab purchased from AbMole
| Molecular Weight | 144321.76 |
| Formula | C6398H9878N1694O2016S48 |
| CAS Number | 339177-26-3 |
| Storage | -80°C for long term |
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