About 4 results found for searched term "EGFR/HER2" (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3217 | AV-412 | EGFR/HER2 |
| MP-412 | ||
| AV-412 is a second-generation, orally bioavailable dual EGFR/HER2 tyrosine kinase inhibitor. | ||
| M5307 | Afatinib dimaleate | EGFR/HER2 |
| BIBW 2992MA2; BIBW2992; Afatinib | ||
| Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. | ||
| M9686 | Tarloxotinib bromide | EGFR/HER2 |
| TH-4000; PR-610 | ||
| Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. | ||
| M14140 | Pyrotinib dimaleate | EGFR/HER2 |
| SHR-1258 dimaleate | ||
| Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. | ||
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