About 5 results found for searched term "EGFR/HER2" (0.039 seconds)
|M3217||AV-412||AV-412 is a second-generation, orally bioavailable dual EGFR/HER2 tyrosine kinase inhibitor.|
|M5307||Afatinib dimaleate||Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.|
|M9686||Tarloxotinib bromide||Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor.|
|M9737||Pyrotinib||Pyrotinib (SHR-1258) is an orally bioavailable, potent and selective EGFR/HER2 dual inhibitor, with IC50 values of 13 and 38 nM, respectively.|
|M14140||Pyrotinib dimaleate||Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively.|
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