| Cat.No. | Name | Information |
|---|---|---|
| M66382 | PLGA(50:50)-OH | PLGA(50:50)-OH is a hydroxyl-terminated polylactic-co-hydroxyacetic acid copolymer, suitable for research into biodegradable nanoparticles, microspheres, sustained-release implants and further surface activation and modification. The hydroxyl end groups serve as starting points for subsequent esterification, carbonate esterification, isocyanate reactions or graft modification, facilitating the construction of PLGA-PEG, PLGA-drug conjugates and multifunctional carrier precursors. |
| M66381 | ZAK-IN-1 | ZAK-IN-1 is an orally active and selective selective leucine-zipper and sterile‑α motif kinase (ZAK) inhibitor with IC50 of 4 nM and KD of 8 nM. ZAK-IN-1 exhibits excellent selectivity against a panel of 403 wild-type kinases. ZAK-IN-1 blocks p38/GATA-4 and JNK/c-Jun signaling and shows promising anti antihypertrophic cardiomyopathy (HCM) efficacy. |
| M66380 | Trimethyl chitosan | Trimethyl chitosan (TMC) is a derivative of Chitosan and a multifunctional polymer. Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic compounds (such as peptides and proteins) and can be used for delivery and synthesis of nanoparticles. |
| M66378 | 6-Hydroxyhexanoic acid | 6-Hydroxyhexanoic acid (6-HHA) is a biochemical reagent. It is used as a precursor to prepare surface active monomers. 6-hydroxyhexanoic acid has a role as a bacterial xenobiotic metabolite. |
| M66377 | L-Tyrosine, N-(2-chloroacetyl)-, cyanomethyl ester | L-Tyrosine, N-(2-chloroacetyl)-, cyanomethyl ester is an amino acid derivative, commonly used as an intermediate in organic synthesis or as a starting material for peptide synthesis. |
| M66374 | Recombinant Mouse IL-1RA Protein (E. coli) | IL-1RA is a member of the interleukin 1 cytokine family. IL-1RA inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. |
| M66373 | Enrofloxacin hydrochloride | Enrofloxacin hydrochloride is an effective antibiotic with antibacterial and antiviral activity. |
| M66371 | Indatuximab | Indatuximab is a chimeric antibody that targets Syndecan-1/CD138. The predicted molecular weight (MW) of Indatuximab is 145.5 kDa. Indatuximab can be used for the research of multiple myeloma and CD138-positive solid tumors. |
| M66370 | BRD4 Inhibitor-20 | BRD4 Inhibitor-20 is a potent orally active bromodomain protein 4 (BRD4) inhibitor. BRD4 Inhibitor-20 has inhibitory activity for BRD4 (BD1) and BRD4 (BD2) with IC50 values of 19 nM and 28 nM, respectively. BRD4 Inhibitor-20 also has anti-proliferation activities in cancer cell lines. |
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