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Cat.No.  Name Information
M21539 TC LPA5 4 TC LPA5 4 is a specific non-lipid LPA5 (GPR92) antagonist (IC50=0.8 μM in LPA5-RH7777 cells). Shows selectivity for LPA5 against 80 other screening targets.TC LPA5 4 was shown to inhibit LPA-induced aggregation of isolated human platelets.TC LPA5 4 inhibits proliferation and migration of thyroid cancer cells.
M21538 Diphenyl diselenide Diphenyl diselenide inhibits δ-aminolevulinic acid dehydrase (δ-ALA-D) in brain, liver, and kidney in vivo.
M21537 Urokinase Urokinase (urokinase) is a proteolytic enzyme. It can be used as a highly effective thrombolytic agent and also has a local vasodilating effect. Used as an antithrombotic compound.
M21536 BAY-069 BAY-069 is a branched-chain amino acid transaminase (BCAT) 1/2 inhibitor. Involved in the synthesis and catabolism of branched-chain amino acids.
M21535 UCB7362 UCB7362 is an oral plasma protease X (PMX) inhibitor that is being developed as an anti-malarial compound.
M21534 AN15368 AN15368 is an oral cleavage and polyadenylate specific factor (CPSF3) inhibitor being developed for use in Chagas disease (also known as American trypanosomiasis).
M21533 BI-0474 BI-0474 is a covalent KRASG12C inhibitor. The IC50 value for GDP-KRAS::SOS1 protein-protein interaction was 7.0 nM. BI-0474 also showed better antitumor activity in non-small cell lung cancer xenograft models.
M21532 JNJ-64264681 JNJ-64264681 is a covalent Bruton tyrosine kinase (BTK) inhibitor under development for hematological malignancies.




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