AbMole BioScience | High Quality Life Science Reagents Supplier

Cat.No.	Name	Information
M13394	HDM201 (Siremadlin)	HDM201 (Siremadlin) is a novel, highly effective and selective inhibitor of P53-MDM2 interaction.
M13393	NVP-CGM097	NVP-CGM097 is a highly effective and selective MDM2 inhibitor with a Ki value of 1.3 nM.
M13392	GeA-69	GeA-69 is a cell-penetrating selective allosteric inhibitor targeting Macrodomain 2 (MD2) with a Kd of 2.1 µM.
M13391	RBN012759	RBN012759 is a potent, selective and orally active PARP14 inhibitor with IC50 values of <3 nM and 5 nM against the human and mouse catalytic domains, respectively. AIDS in the anti-tumor immune response.
M13390	C527	C527 is an inhibitor of pan-dub enzyme with an IC50 value of 0.88 μM.
M13389	ACBI1	ACBI1 is an effective and synergistic PROTAC inhibitor of SMARCA2, SMARCA4 and PBRM1, with DC50 of 6 nM, 11 nM and 32 nM in MV-4-11 cells, respectively. ACBI1 can induce antiproliferative effect and apoptosis.
M13388	RP-6306	RP-6306 is the only inhibitor of PKMYT1 currently available in the clinic, which is synthetically fatal to CCNE1 amplification, FBXW7 deletion or other specific mutations.
M13387	SNDX-5613	SNDX-5613 is an effective and selective Menin-MLL binding inhibitor with Ki of 0.15 nM. Sndx-5613 can be used to study MLL gene rearrangement in acute leukemia, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).