| Cat.No. | Name | Information |
|---|---|---|
| M66355 | Cy7-Glucose | Cy7-Glucose is a fluorescent probe consisting of a covalent bond between the cyanine dye CY7 and a glucose molecule, and is widely used in near-infrared (NIR) optical imaging. The glucose moiety acts as a targeting group, enabling recognition by glucose transporters on the cell surface (such as the GLUT family) and mediating endocytosis, thereby achieving selective labelling of metabolically active cells. It combines the excellent near-infrared optical properties of Cy7 with the biological metabolic activity of glucose, and is primarily used for imaging, metabolic tracking and drug delivery assessment in biomedical research. |
| M66354 | Ezurpimtrostat | Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. |
| M66353 | Levomefolic acid (>97%) | Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. |
| M66352 | Lactoperoxidase, bovine milk | Lactoperoxidase, bovine milk, an antimicrobial protein, is a mammalian heme peroxidase superfamily member isolated from bovine milk with antibacterial activity. Lactoperoxidase, bovine milk can be used for the research of bacterial infections and cancer. |
| M66351 | Fluoresterol | Fluoresterol (22-NBD Cholesterol) is a cholesterol-specific fluorescent probe with cholesterol-mimicking binding properties. Fluoresterol is ineffective orally and does not cross the blood-brain barrier. Fluoresterol specifically binds to cholesterol transport-related proteins (such as ABCA1 and ABCG1) and is primarily used in cholesterol metabolism research, particularly for the visualization and quantitative analysis of cholesterol absorption, efflux, intracellular transport efficiency, and reverse cholesterol transport (RCT) processes. |
| M66350 | Recombinant Human Noggin Protein (CHO) | Recombinant Human Noggin Protein can bind to ligands of the transforming growth factor-β family and regulate its activity by inhibiting its pathway with signal receptors. Noggin was initially identified as a BMP-4 antagonist, and its effect is essential for the normal formation of the head and other back structures. |
| M66349 | Lifeact peptide | Lifeact peptide is a 17-amino-acid sequence derived from an actin-binding domain of yeasts. Lifeact peptide can specifically bind to actin microfilaments and can be used for the labeling of actin. |
| M66348 | Recombinant Human Mucin-1/MUC1 Protein (HEK293, C-6His) | Mucin 1, known as MUC1, is a multifunctional protein expressed on the apical surface of most epithelial cells. MUC1/Muc1 in promotes cell growth and survival. MUC1 does have an exceptionally strong glycan-dependent apical targeting signal that can redirect a basolaterally expressed protein to the apical cell surface in polarized epithelia. Mucin-1/MUC1 protein and its α subunit have dual functions of adhesion and anti-adhesion proteins, forming a protective layer on epithelial cells. |
| M66344 | MGD-28 | MGD-28 is a potent, orally active, Cereblon (CRBN)-dependent IKAROS protein degrader that degrades IKZF1 (DC50=3.8 nM), IKZF2 (DC50=56.3 nM), and IKZF3 (DC50=7.1 nM) in a dose-dependent manner. In addition, MGD-4 also degrades CK1α (DC50=7.8 nM). |
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