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Brassinolide

Cat. No. M9314
Brassinolide Structure
Synonym:

Brassin lactone; BRs; 6DCS; BL

Size Price Availability Quantity
10mg USD 105  USD105 In stock
25mg USD 235  USD235 In stock
50mg USD 375  USD375 In stock
100mg USD 585  USD585 In stock
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Quality Control & Documentation
Biological Activity

Brassinolide is a naturally occurring plant hormone that promotes growth, increases yields for grain and fruit crops, and makes plants more resistant to drought and cold weather. Brassinolide could induce a time and concentration-dependent cytotoxicity in PC-3 cells. Treatment with brassinolide triggers a time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 and marked accumulation in G2/M phase of cell cycle.

Product Citations
Chemical Information
Molecular Weight 480.68
Formula C28H48O6
CAS Number 72962-43-7
Solubility (25°C) DMSO: ≥ 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Wu YD, et al. Pharmazie. Brassinolide, a plant sterol from pollen of Brassica napus L., induces apoptosis in human prostate cancer PC-3 cells.

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Keywords: Brassinolide, Brassin lactone; BRs; 6DCS; BL supplier, Plant growth regulators, inhibitors, activators


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