Brassinolide is a naturally occurring plant hormone that promotes growth, increases yields for grain and fruit crops, and makes plants more resistant to drought and cold weather. Brassinolide could induce a time and concentration-dependent cytotoxicity in PC-3 cells. Treatment with brassinolide triggers a time-dependent decrease in the expression of anti-apoptotic protein Bcl-2 and marked accumulation in G2/M phase of cell cycle.
J Exp Bot. 2021 Jun 22;72(13):4721-4743.
Orchestration of plant development and defense by indirect crosstalk of salicylic acid and brassinosteorid signaling via transcription factor GhTINY2
Brassinolide purchased from AbMole
| Molecular Weight | 480.68 |
| Formula | C28H48O6 |
| CAS Number | 72962-43-7 |
| Solubility (25°C) | DMSO: ≥ 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Plant growth regulators Products |
|---|
| Thioanisole
Thioanisole is used as a raw material for the synthesis of antibiotics and insecticides. |
| Potassium carbonate
Potassium carbonate is a common potassium salt as well as a common potassium fertilizer. |
| Ethyl chloroacetate
Ethyl chloroacetate is used as a raw material for the preparation of the insecticide azoxystrobin and the herbicide ethyl chlormequat, as well as for the synthesis of 5-fluorouracil (5-FU). |
| Chloranil
Chloranil is a fungicide that can be used to treat seeds and bulbs of crops against fungal diseases. |
| Ethyl cyanoglyoxylate-2-oxime
Ethyl cyanoglyoxylate-2-oxime is used as a raw material for insecticides, fungicides, and other pesticides to control pests and diseases in a wide variety of crops. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
