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Teduglutide

Cat. No. M10249

All AbMole products are for research use only, cannot be used for human consumption.

Teduglutide Structure
Synonym:

ALX 0600; Gattex; Revestive; TAK 633

Size Price Availability Quantity
1mg USD 108  USD108 In stock
5mg USD 216  USD216 In stock
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Quality Control & Documentation
Biological Activity

Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue used for the treatment of short-bowel syndrome. Teduglutide has similar binding affinity, agonist potency, and agonist efficacy as GLP-2 in assays with the rat GLP-2 receptor. Administration of teduglutide to rats gave a significant increase in small intestine weight and an increase in the height of intestinal villi.

Product Citations
Chemical Information
Molecular Weight 3752.08
Formula C164H252N44O55S
CAS Number 197922-42-2
Solubility (25°C) DMSO 30 mg/mL
Storage -20°C, sealed, protect from light
References

[1] Beatrice E Rosete, et al. Expert Rev Gastroenterol Hepatol. Teduglutide for pediatric short bowel syndrome patients

[2] No authors listed. Aust Prescr. Teduglutide for short bowel syndrome

[3] Samuel A Kocoshis, et al. JPEN J Parenter Enteral Nutr. Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24-Week, Phase III Study

[4] Palle B Jeppesen, et al. Gastroenterology. Factors Associated With Response to Teduglutide in Patients With Short-Bowel Syndrome and Intestinal Failure

[5] Palle B Jeppesen, et al. Gastroenterology. Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

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Keywords: Teduglutide, ALX 0600; Gattex; Revestive; TAK 633 supplier, GLP Receptor, inhibitors, activators

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