All AbMole products are for research use only, cannot be used for human consumption.
Dulaglutide (Activated main chain) is a glucagon-like peptide-1 receptor agonist (GLP-1 agonist) consisting of GLP-1(7-37) covalently linked to an Fc fragment of human IgG4. Dulaglutide binds to glucagon-like peptide 1 receptors, slowing gastric emptying and increases insulin secretion by pancreatic Beta cells. Simultaneously the compound reduces the elevated glucagon secretion by inhibiting alpha cells of the pancreas. GLP-1 is normally secreted by L cells of the gastrointestinal mucosa in response to a meal.
Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly
| Molecular Weight | 3213.2 |
| CAS Number | 923950-08-7 |
| Solubility (25°C) | Soluble in water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Nadkarni P, et al. Prog Mol Biol Transl Sci. Regulation of glucose homeostasis by GLP-1.
| Related GLP Receptor Products |
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Amycretin is a novel, potentially first-in-class, long-acting co-agonist of GLP-1 and the amyloid receptor (AMYR) for obesity-related studies. |
| NM-003
NM-003 is a GLP-2R agonist that can be used in studies related to inflammatory bowel disease. |
| NB-1002
NB-1002 is a GLP-2R agonist that can be used in studies related to short bowel syndrome. |
| MOD-15014
MOD-15014 is a GLP-2R modulator that can be used in studies related to short bowel syndrome. |
| HM-15912
HM-15912 is a GLP-2R agonist that can be used in studies related to short bowel syndrome. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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