Free shipping on all orders over $ 500

Gastrin-I (human)

Cat. No. M9320
Gastrin-I (human) Structure
Synonym:

Gastrin-1

Size Price Availability Quantity
1mg USD 100  USD100 In stock
5mg USD 300  USD300 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. Gastrin-I (1.5, 5, 15 and 45 nmol/kg, i.v.) increases pepsinogen and acid secretion in rats.

Chemical Information
Molecular Weight 2098.20
Formula C97H124N20O31S
CAS Number 10047-33-3
Solubility (25°C) Water 10 mM
Storage -20°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Blandizzi C, et al. Eur J Pharmacol. CCK1 and CCK2 receptors regulate gastric pepsinogen secretion.

Related Cholecystokinin Receptor Products
PD 135158

PD 135158 (CAM 1028) is a selective CCKB receptor antagonist with an IC50 of 2.8 nM against mouse cortex CCKB.

[Leu15]-Gastrin I (human)

[Leu15]-Gastrin I (human) is a peptide that acts via cholecystokinin (CCK) or CCK-B receptor (CCK-BR).

Gastrin I (rat) TFA

Gastrin I (rat) TFA is a peptide hormone, which can stimulate gastric acid secretion potently.

Mini Gastrin I, human TFA 

Mini Gastrin I, human (TFA) is a shorter version of human gastrin, consists of amino acids 5-17 of the parent peptide.

Mini Gastrin I, human 

Mini Gastrin I, human is a shorter version of human gastrin, consists of amino acids 5-17 of the parent peptide.

  Catalog
Abmole Inhibitor Catalog




Keywords: Gastrin-I (human), Gastrin-1 supplier, Cholecystokinin Receptor, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.