All AbMole products are for research use only, cannot be used for human consumption.
Ceruletide is similar chemically and biologically to the human gastrointestinal hormones cholecystokinin-pancreozymin (CCK) and gastrin II.
In vivo, Ceruletide (0.4-0.5 mcg/kg, i.v.; 3-4 mcg/kg, s.c.) results in emesis and evacuation of the bowel in the intact conscious dog, and recovery is complete 15-30 min after i. v. administration and 2-4 hr after s.c. administration. Ceruletide (5-15 ng/kg, i.v.) shows a marked spasmogenic effect on the pylorus of rats. Ceruletide also reduces blood pressure in anesthetized dogs.
J Interferon Cytokine Res. 2023 Oct;43(10):455-468.
The Role and Potential Regulatory Mechanism of STING Modulated Macrophage Apoptosis and Differentiation in Severe Acute Pancreatitis-Associated Lung Injury
Ceruletide purchased from AbMole
Basic Clin Pharmacol Toxicol. 2021 Nov;129(5):357-368.
RORγt inhibitor SR1001 alleviates acute pancreatitis by suppressing pancreatic IL‐17‐producing Th17 and γδ‐T cells in mice with ceruletide‐induced pancreatitis
Ceruletide purchased from AbMole
Molecular Weight | 1352.41 |
Formula | C58H73N13O21S2 |
CAS Number | 17650-98-5 |
Solubility (25°C) | DMSO ≥ 50 mg/mL Water 2 mg/mL |
Storage | -20°C, protect from light, dry, sealed |
[2] Steinle AU, et al. Gastroenterology. NF-kappaB/Rel activation in cerulein pancreatitis.
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