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Ceruletide

Cat. No. M9316

All AbMole products are for research use only, cannot be used for human consumption.

Ceruletide Structure
Synonym:

Caerulein; Cerulein; FI-6934

Size Price Availability Quantity
500ug USD 110  USD110 In stock
1mg USD 180  USD180 In stock
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Quality Control & Documentation
Biological Activity

Ceruletide is similar chemically and biologically to the human gastrointestinal hormones cholecystokinin-pancreozymin (CCK) and gastrin II.

In vivo, Ceruletide (0.4-0.5 mcg/kg, i.v.; 3-4 mcg/kg, s.c.) results in emesis and evacuation of the bowel in the intact conscious dog, and recovery is complete 15-30 min after i. v. administration and 2-4 hr after s.c. administration. Ceruletide (5-15 ng/kg, i.v.) shows a marked spasmogenic effect on the pylorus of rats. Ceruletide also reduces blood pressure in anesthetized dogs.

Product Citations
Chemical Information
Molecular Weight 1352.41
Formula C58H73N13O21S2
CAS Number 17650-98-5
Solubility (25°C) DMSO ≥ 50 mg/mL
Water 2 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Bridger N, et al. J Vet Intern Med. Comparison of postprandial and ceruletide serum bile acid stimulation in dogs.

[2] Steinle AU, et al. Gastroenterology. NF-kappaB/Rel activation in cerulein pancreatitis.

[3] Vincent ME, et al. Pharmacotherapy. Pharmacology, clinical uses, and adverse effects of ceruletide, a cholecystokinetic agent.

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Keywords: Ceruletide, Caerulein; Cerulein; FI-6934 supplier, Animal Modeling, inhibitors, activators

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