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Olive oil

Cat. No. M15070
Olive oil Structure
Size Price Availability Quantity
100mL USD 50  USD50 In stock
500mL USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Olive oil is an oil extracted from the olives (Olea europaea). The health benefits of olive oil result from its higher proportion of monounsaturated fats, as well as its antioxidant constituents: hydroxytyrosol, oleuropein and oleocanthal.

Slightly soluble in ethanol (95%); miscible with ether, chloroform, light petroleum (50–70°C), and carbon disulfide.

Product Citations
Chemical Information
CAS Number 8001-25-0
Solubility (25°C) miscible with ether and chloroform and carbon disulfide
Storage 2-8°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Constantinos Salis, et al. Adv Exp Med Biol. Olive Oil Polyphenols in Neurodegenerative Pathologies

[2] Antonio Maria Borz, et al. Nutrients. Olive Oil Effects on Colorectal Cancer

[3] Monika Gorzynik-Debicka, et al. Int J Mol Sci. Potential Health Benefits of Olive Oil and Plant Polyphenols

[4] Cristina Angeloni, et al. Int J Mol Sci. Bioactivity of Olive Oil Phenols in Neuroprotection

[5] Luca Fernndez del Ro, et al. Molecules. Olive Oil and the Hallmarks of Aging

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