Bulevirtide is a first-in-class entry inhibitor for the treatment of chronic Hepatitis D infection. Bulevirtide prevents Hepatitis D entry into cells. It is effective in the reduction of Hepatitis D virus (HDV) RNA levels and improvement of liver inflammation in cases of Hepatitis D infection. In rats, bulevirtide administered by subcutaneous injection is rapidly absorbed with a Cmax of 4 to 6 hours.
Int J Biol Macromol. 2023 Jun 22;245:125539.
Strongylocentrotus nudus egg polysaccharide (SEP) suppresses HBV replication via activation of TLR4-induced immune pathway
Bulevirtide purchased from AbMole
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Related Peptides Products|
|Trypsin Inhibitor (from Soybean)
Trypsin inhibitor is an alkaline polypeptide consisting of 58 amino acid residues with a pear shape throughout the molecule and a lysine activity center. It can compete with the activity center of many proteases for a lysyl group and inhibit their activities.
(D-His2,D-Trp6)-LHRH is a peptide that can be discovered by peptide screening. Peptide screening is a research tool that assembles active peptides primarily by immunoassay. It can be used for protein interactions, functional analysis, antigenic epitope screening, and the development and study of active molecules.
|Ghrelin (mouse, rat) TFA
Ghrelin (mouse, rat) TFA is a gastrointestinal secretory-generated, endogenous brain-gut peptide consisting of 28 amino acids that possesses a variety of physiological functions including appetite stimulation, and is also an endogenous agonist peptide for the ghrelin (GHS) receptor.
LIP1 (human) is a polypeptide produced from the anterior region of nerve growth factor (NGF) containing 29 amino acids that induces F-actin rearrangement, phosphorylates TrkA and Akt, and has antiproliferative as well as neuroprotective activities. Sequence: ARSAPAAAIAARVAGQTRNITVDPRLFKK
|Kisspeptin-10, human ACETATE
Kisspeptin-10, human ACETATE is the acetate form of Kisspeptin-10 and is also a potent vasoconstrictor and angiogenesis inhibitor that inhibits tumor metastasis through its receptor GPR54.Kisspeptin-10/GPR54 signaling through NFATc4-mediated BMP2 expression to induces osteoblast differentiation through NFATc4-mediated BMP2 expression.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.