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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M45249 DCBY02 DCBY02 is a monoclonal antibody targeting CD93 for studies related to solid tumors.
M45157 OS2966 OS2966 is a first-in-class (first-in-class) neutralizing anti-CD29 monoclonal antibody that selectively modulates CD29 (integrin b1 subunit) and can be used in glioblastoma-related studies.
M40939 Rat IgG2b Isotype Control In vivo Rat IgG2b Isotype Control In vivo monoclonal antibody (Clone:1-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
M40938 Rat IgG2a Isotype Control In vivo Rat IgG2a Isotype Control In vivo can be used as an isotype-matched control for rat IgG2a antibodies.
M40937 Suciraslimab Suciraslimab is a potentially first-in-class monoclonal antibody against the B-cell target CD22, which can help change CD22 from cis-binding to trans-binding and form a stable CD22 trans-binding structure, thereby restoring B-cell tolerance to its own antigens and inhibiting B-cells from undergoing a series of related immune responses to attack its own organism.
M40936 Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo Anti-Mouse CD4 (Clone GK1.5) antibody recognizes an epitope on Mouse CD4.
M40935 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo Anti-Mouse IFNγ (interferon gamma) (Clone H22) antibody recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
M40934 Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40918 Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils.
M40909 Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo Anti-Mouse CD8a (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes.
M40876 Ebdarokimab Ebdarokimab is a monoclonal antibody to IL-12p40/IL-23 that can be used in studies related to inflammatory bowel disease (IBD).
M40875 Brazikumab Brazikumab is a human IgG2 monoclonal antibody targeting IL-23 that selectively binds to the p19 subunit of IL-23 and has a KD value of 0.138 nM against human IL-23 for Crohn's disease (CD).
M40856 Anti-Mouse CD4 Antibody (Clone YTS191) In vivo Anti-Mouse CD4 (Clone YTS191) recognizes an epitope on mouse CD4. CD4 is expressed on most thymocytes, MHC class II-restricted T cells, a subset of NKT cells, and subsets of dendritic cells and macrophages.
M40854 Elranatamab Elranatamab is a humanized IgG2ҡ bispecific T-cell inducing antibody that targets CD3 and B-cell maturation antigen (BCMA) on the surface of T-cells, resulting in activation of T-cells and the release of a variety of pro-inflammatory cytokines that lead to multiple myeloma cell lysis. It can be used in studies related to relapsed or refractory multiple myeloma (RRMM).
M40830 Anti-Mouse CD3ε Antibody In vivo Anti-Mouse CD3ε (Clone 145-2C11) recognizes an epitope on mouse CD3ε. CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
M40828 Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo Anti-Mouse CTLA-4 (Clone 9H10) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40812 Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo.
M40806 Anti-Mouse NK1.1 Antibody In vivo This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily.
M40797 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.
M40795 Anti-Mouse IL-4 Antibody In vivo IL-4 antibody, 11B11, recognizes mouse IL-4, also known as B-cell differentiation factor (BCDF) and B-cell stimulatory factor (BSF1).

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