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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M55700 Anti-human CD52 mAb (HEK293)
M55669 Anti-Mouse IFNß (interferon beta) Antibody (Clone HDß-4A7) In vivo Anti-Mouse Interferon-beta (IFN-ß) (Clone HDß-4A7) recognizes an epitope on Mouse IFN-ß and binds specifically to murine IFNß and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms.
M55641 Cantuzumab Cantuzumab is a monoclonal antibody that can binds the CanAg antigen.
M55206 Lintuzumab Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia.
M55046 Inetetamab Inetetamab is a monoclonal antibody binding to domain IV of HER2 receptor. Inetetamab shows antitumor activities when used alone or together with tyrosine kinase inhibitors.
M55043 Cinpanemab Cinpanemab (BIIB054) is a human-derived monoclonal antibody that binds to α-synuclein. Cinpanemab can be used for the research of Parkinson's disease.
M55042 Cofetuzumab Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7.
M55041 Crizanlizumab Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs).
M55035 Rosnilimab Rosnilimab is a novel PD-1 checkpoint agonist antibody that reduces overactive T cell inflammation. Rosnilimab optimizes PD-1+ T cell inhibitory signaling by enabling tight immune synapse formation. Rosnilimab restores immune balance bringing T cell composition to a less activated state.
M54716 Trontinemab Trontinemab is a bispecific human IgG1-κ antibody that targets amyloid β A4 precursor protein (APP) and transferrin receptor (TFRC).Trontinemab may be used in Alzheimer's disease-related studies.
M54553 Erfonrilimab Erfonrilimab is a humanized single-domain bispecific antibody-Fc fusion protein (VH-VH-h-CH2-CH3 dimer) targeting the immune checkpoints PD-L1 and CTLA-4.
M54551 Rademikibart Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases.
M54547 Enlonstobart Enlonstobart is a recombinant humanized anti-PD-1 IgG4ҡ monoclonal antibody that can be used for tumor-related studies.
M50198 Pelgifatamab Pelgifatamab is a monoclonal antibody targeting prostate cancer-specific membrane antigen (PSMA) for prostate cancer-related studies.
M49947 Ifabotuzumab Ifabotuzumab is an IgG1κ antibody (KD=610 pM) targeting EphA3. Ifabotuzumab is able to cause apoptosis of tumor cells and activate antibody-dependent cell-mediated cytotoxicity (ADCC), which disrupts the tumor vascular system. In addition, Ifabotuzumab reduces idiopathic pulmonary fibrosis (IPF) CCR10+ cells and ameliorates pulmonary fibrosis.
M49822 Tanruprubart Tanruprubart (ANX005) is a monoclonal antibody that blocks the activation of the entire classical signaling pathway by inhibiting complement protein C1q, which is upstream of the complement cascade reaction, while also maintaining the functional integrity of other complement pathways. It can be used in studies related to Guillain-Barre Syndrome (GBS).
M49458 Raludotatug Raludotatug is a humanized anti-CDH6 IgG1 monoclonal antibody. Raludotatug has antitumor activity and can be used to synthesize the ADC molecule Raludotatug deruxtecan. Raludotatug deruxtecan is a potential first-in-class antibody-drug coupling (ADC) targeting CDH6 for studies related to ovarian cancer.
M49437 Afimkibart Afimkibart (PF-06480605) is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC).
M45360 LYT-200 Research Grade Anti-Human LGALS9 (LYT-200) is a monoclonal antibody that targets galectin-9 (galectin-9) and has antitumor activity.
M45266 Linvoseltamab Linvoseltamab is a bispecific antibody targeting BCMA (TNFRSF17) and CD3. Linvoseltamab is used in studies related to relapsed/refractory multiple myeloma (R/R MM).

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