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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M55669 Anti-Mouse IFNß (interferon beta) Antibody (Clone HDß-4A7) In vivo Anti-Mouse Interferon-beta (IFN-ß) (Clone HDß-4A7) recognizes an epitope on Mouse IFN-ß and binds specifically to murine IFNß and does not bind murine IFNg or several different IFNa species (a-1,4,5 or 13); HDb-4A7 binds both recombinant and natural forms.
M55206 Lintuzumab Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia.
M54716 Trontinemab Trontinemab is a bispecific human IgG1-κ antibody that targets amyloid β A4 precursor protein (APP) and transferrin receptor (TFRC).Trontinemab may be used in Alzheimer's disease-related studies.
M54551 Rademikibart Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases.
M54547 Enlonstobart Enlonstobart is a recombinant humanized anti-PD-1 IgG4ҡ monoclonal antibody that can be used for tumor-related studies.
M49822 ANX005 ANX005 is a monoclonal antibody that blocks the activation of the entire classical signaling pathway by inhibiting complement protein C1q, which is upstream of the complement cascade reaction, while also maintaining the functional integrity of other complement pathways. It can be used in studies related to Guillain-Barre Syndrome (GBS).
M45360 LYT-200 Research Grade Anti-Human LGALS9 (LYT-200) is a monoclonal antibody that targets galectin-9 (galectin-9) and has antitumor activity.
M40939 Rat IgG2b Isotype Control In vivo Rat IgG2b Isotype Control In vivo monoclonal antibody (Clone:1-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
M40936 Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo Anti-Mouse CD4 (Clone GK1.5) antibody recognizes an epitope on Mouse CD4.
M40935 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo Anti-Mouse IFNγ (interferon gamma) (Clone H22) antibody recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
M40934 Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40918 Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils.
M40909 Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo Anti-Mouse CD8a (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes.
M40875 Brazikumab Brazikumab is a human IgG2 monoclonal antibody targeting IL-23 that selectively binds to the p19 subunit of IL-23 and has a KD value of 0.138 nM against human IL-23 for Crohn's disease (CD).
M40856 Anti-Mouse CD4 Antibody (Clone YTS191) In vivo Anti-Mouse CD4 (Clone YTS191) recognizes an epitope on mouse CD4. CD4 is expressed on most thymocytes, MHC class II-restricted T cells, a subset of NKT cells, and subsets of dendritic cells and macrophages.
M40830 Anti-Mouse CD3ε Antibody In vivo Anti-Mouse CD3ε (Clone 145-2C11) recognizes an epitope on mouse CD3ε. CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
M40828 Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo Anti-Mouse CTLA-4 (Clone 9H10) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40812 Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo.
M40806 Anti-Mouse NK1.1 Antibody In vivo This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily.
M40797 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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