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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M49822 ANX005 ANX005 is a monoclonal antibody that blocks the activation of the entire classical signaling pathway by inhibiting complement protein C1q, which is upstream of the complement cascade reaction, while also maintaining the functional integrity of other complement pathways. It can be used in studies related to Guillain-Barre Syndrome (GBS).
M45360 LYT-200 Research Grade Anti-Human LGALS9 (LYT-200) is a monoclonal antibody that targets galectin-9 (galectin-9) and has antitumor activity.
M40939 Rat IgG2b Isotype Control In vivo Rat IgG2b Isotype Control In vivo monoclonal antibody (Clone:1-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
M40936 Anti-Mouse CD4 Antibody (Clone GK1.5) In vivo Anti-Mouse CD4 (Clone GK1.5) antibody recognizes an epitope on Mouse CD4.
M40935 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone H22) In vivo Anti-Mouse IFNγ (interferon gamma) (Clone H22) antibody recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
M40934 Anti-Mouse CTLA-4 Antibody (Clone 9D9) In vivo Anti-Mouse CTLA-4 Antibody (Clone 9D9) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40918 Anti-Mouse Ly6G Antibody (Clone 1A8) In vivo Anti-Mouse Ly6G antibody (Clone 1A8) In vivo recognizes an epitope on mouse Ly6G. Ly6G is expressed by neutrophils.
M40909 Anti-Mouse CD8a Antibody (Clone 53-6.7) In vivo Anti-Mouse CD8a (Clone 53-6.7) In vivo recognizes Lyt 2. Clone 53-6.7 competes with clone 5H10-1 for binding to thymocytes.
M40875 Brazikumab Brazikumab is a human IgG2 monoclonal antibody targeting IL-23 that selectively binds to the p19 subunit of IL-23 and has a KD value of 0.138 nM against human IL-23 for Crohn's disease (CD).
M40856 Anti-Mouse CD4 Antibody (Clone YTS191) In vivo Anti-Mouse CD4 (Clone YTS191) recognizes an epitope on mouse CD4. CD4 is expressed on most thymocytes, MHC class II-restricted T cells, a subset of NKT cells, and subsets of dendritic cells and macrophages.
M40830 Anti-Mouse CD3ε Antibody In vivo Anti-Mouse CD3ε (Clone 145-2C11) recognizes an epitope on mouse CD3ε. CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
M40828 Anti-Mouse CTLA-4 Antibody (Clone 9H10) In vivo Anti-Mouse CTLA-4 (Clone 9H10) recognizes an epitope on mouse CTLA-4. CTLA-4 is expressed on activated T and B lymphocytes.
M40812 Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo Anti-Mouse Ly-6G/Ly-6C Antibody (Clone RB6-8C5) In vivo has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo.
M40806 Anti-Mouse NK1.1 Antibody In vivo This NK1.1 antibody (clone PK136) recognizes mouse NK1.1. NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily.
M40797 Anti-Mouse IFNγ (interferon gamma) Antibody (Clone XMG1.2) In vivo Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.
M40795 Anti-Mouse IL-4 Antibody In vivo IL-4 antibody, 11B11, recognizes mouse IL-4, also known as B-cell differentiation factor (BCDF) and B-cell stimulatory factor (BSF1).
M40769 Anti-Mouse/Human TGF-β Antibody In vivo This Mouse Anti-Human/Mouse TGF-β clone Clone 1D11.16.8 recognizes an epitope on Human/Mouse TGF-β1,2,3.
M40768 Anti-Mouse IFNAR-1 Antibody In vivo IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β.
M40764 Anti-Mouse PD-L1 mAb In vivo
M40599 Ocrelizumab Ocrelizumab is a humanized anti-CD20 monoclonal antibody that may be used in studies related to multiple sclerosis.

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