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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M40769 Anti-Mouse/Human TGF-β Antibody In vivo This Mouse Anti-Human/Mouse TGF-β clone Clone 1D11.16.8 recognizes an epitope on Human/Mouse TGF-β1,2,3.
M40768 Anti-Mouse IFNAR-1 Antibody In vivo IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β.
M40764 Anti-Mouse PD-L1 mAb In vivo
M40609 Eblasakimab Eblasakimab is a potential first-in-class, novel monoclonal antibody that targets the IL-13 receptor alpha 1 subunit (IL-13Rα1) and inhibits signaling of the pro-inflammatory cytokines IL-4 and IL-13. It can be used in studies related to atopic dermatitis (AD).
M40602 Alacizumab Alacizumab is a monoclonal antibody against VEGFR2 that can be used in cancer-related studies.
M40600 Ebronucimab Ebronucimab is a monoclonal antibody to PCSK9 that can be used in studies related to hypercholesterolemia.
M40599 Ocrelizumab Ocrelizumab is a humanized anti-CD20 monoclonal antibody that may be used in studies related to multiple sclerosis.
M40598 Serclutamab Serclutamab is a monoclonal antibody to EGFR that can be used in studies related to solid tumors.
M40596 Pimurutamab Pimurutamab is a monoclonal antibody to EGFR that can be used in tumor-related studies.
M40595 Pidilizumab Pidilizumab is a humanized IgG1k anti-PD-1 monoclonal antibody that can be used in studies related to diffuse large B-cell lymphoma (DLBCL).
M40593 Brolucizumab Brolucizumab (DLX1008) is a single-chain variable fragment (scFv) anti-VEGF-A antibody exhibiting an exceptionally low picomolar binding affinity (K D = 1.05 pM). Brolucizumab can be used in studies related to macular degeneration.
M40592 Certolizumab Certolizumab is a recombinant, polyethylene glycolated, antigen-binding fragment of a humanized monoclonal antibody that selectively targets and neutralizes tumor necrosis factor (TNF)-alpha, and may be used in psoriasis-related studies.
M40552 Osemitamab Osemitamab (TST001) is a recombinant humanized, IgG1 antibody targeting CLDN18.2, consisting of the human mouse monoclonal TST001 γ-1 chain polymerized via disulfide bonding with the human mouse monoclonal TST001 κ-chain dimer (ACI). It can be used in studies related to bile duct tumors.
M31386 Epcoritamab Epcoritamab is a novel bispecific IgG1k/λ antibody targeting CD3 and CD20 that activates T cells and directs them to kill malignant CD20+ B cells.Epcoritamab has antitumor activity and may be used in studies related to RR diffuse large B-cell lymphoma (DLBCL).
M31300 Faricimab Faricimab is a bispecific antibody targeting Ang II and VEGF-A for studies related to eye disease and cardiovascular disease.
M31121 Dinutuximab Dinutuximab is an anti-disialytic ganglioside antigen (GD2) antibody with anticancer activity for studies related to pediatric neuroblastoma.
M25443 Necitumumab Necitumumab is a second-generation fully humanized immunoglobulin G1 (IgG1), epidermal growth factor (EGFR) receptor monoclonal antibody that specifically blocks the ligand binding site of EGFR.
M25387 Daclizumab Daclizumab (Zenapax) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab (Zenapax) reversibly binds to CD25and prevents the interaction of IL-2 with the IL-2R-HA.
M25373 Zilovertamab Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.
M25367 Amlitelimab Amlitelimab is a potential best-in-class (mAb) anti-OX40 ligand (OX40L) monoclonal antibody.Amlitelimab inhibits OX40-OX40L interaction and may be used in studies related to atopic dermatitis.

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