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Humanized monoclonal antibody (mAb)

Cat.No.  Name Information
M54717 GYM329 GYM329 is a monoclonal antibody that binds to and inhibits activation of the muscle growth inhibitor (myostatin) precursor protein target.
M54690 HB0017 HB0017 is a monoclonal antibody that targets interleukin-17 (IL-17) and selectively binds IL-17A, thereby preventing IL-1717A from binding to its receptor.
M54591 SAR-442501 SAR-442501 is a novel anti-FGFR3 monoclonal antibody for studies related to achondroplasia (ACH).
M54557 Chilob7/4 Chilob7/4 is a chimeric agonist anti-CD40 IgG1 antibody that can be used for tumor-related studies.
M54555 ABBV-428 ABBV-428 is a bispecific antibody targeting CD40/Mesothelin and can be used in studies related to solid tumors.
M54553 Erfonrilimab Erfonrilimab is a humanized single-domain bispecific antibody-Fc fusion protein (VH-VH-h-CH2-CH3 dimer) targeting the immune checkpoints PD-L1 and CTLA-4.
M54552 Anselamimab Anselamimab is a human IgG1κ anti-amyloidogenic fibrillar antibody targeting serum amyloid A1 (SAA1) for studies related to AL-type amyloidosis.
M54551 Rademikibart Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases.
M54550 Stapokibart Stapokibart is a humanized monoclonal antibody targeting IL-4Rα that blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit, IL-4Rα. Stapokibart is able to interact with IL-4Rα in humans, cynomolgus monkeys, and rats, and can be used in atopic dermatitis research.
M54549 AZD3152 AZD3152 is a monoclonal antibody targeting SARS-CoV-2.
M54548 Benmelstobart Benmelstobart is an anti-PD-L1 humanized IgG1ҡ monoclonal antibody that can be used for tumor-related studies.
M54547 Enlonstobart Enlonstobart is a recombinant humanized anti-PD-1 IgG4ҡ monoclonal antibody that can be used for tumor-related studies.
M54528 Dargistotug Dargistotug is a fully human IgG1 monoclonal antibody targeting T-cell immunoglobulin and the ITIM structural domain (TIGIT) that induces an immune response targeting cancer cells by blocking the TIGIT pathway.
M54521 Narlumosbart Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB).
M50212 PRX012 PRX012 is a potential best-in-class (BIC) anti-amyloid β (Aβ) monoclonal antibody that stimulates microglia-mediated clearance of amyloid deposits in brain tissues, and can be used in studies related to Alzheimer's disease (AD).
M50211 AL-002 AL-002 is a humanized monoclonal antibody targeting myeloid triggered receptor 2 (TREM2) that improves cell survival and proliferation and increases microglia activity by activating TREM2 signaling, and can be used in studies related to Alzheimer's disease (AD).
M50201 BAY-3401016 BAY-3401016 is a monoclonal antibody targeting SEMA3A for studies related to Alport syndrome.
M50200 BAY-3018250 BAY-3018250 is a monoclonal antibody targeting α2-antifibrinolytic enzyme (A2AP) for use in studies related to cardiovascular disease.
M50198 Pelgifatamab Pelgifatamab is a monoclonal antibody targeting prostate cancer-specific membrane antigen (PSMA) for prostate cancer-related studies.
M50169 IPG0521 IPG0521 is a bifunctional antibody targeting CCR8, which can block CCR8 signaling with high intensity and weak ADCC function, and can effectively inhibit the growth of multiple tumor types in homologous and immunohumanized mouse models.

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