Cat.No. | Name | Information |
---|---|---|
M54717 | GYM329 | GYM329 is a monoclonal antibody that binds to and inhibits activation of the muscle growth inhibitor (myostatin) precursor protein target. |
M54690 | HB0017 | HB0017 is a monoclonal antibody that targets interleukin-17 (IL-17) and selectively binds IL-17A, thereby preventing IL-1717A from binding to its receptor. |
M54591 | SAR-442501 | SAR-442501 is a novel anti-FGFR3 monoclonal antibody for studies related to achondroplasia (ACH). |
M54557 | Chilob7/4 | Chilob7/4 is a chimeric agonist anti-CD40 IgG1 antibody that can be used for tumor-related studies. |
M54555 | ABBV-428 | ABBV-428 is a bispecific antibody targeting CD40/Mesothelin and can be used in studies related to solid tumors. |
M54553 | Erfonrilimab | Erfonrilimab is a humanized single-domain bispecific antibody-Fc fusion protein (VH-VH-h-CH2-CH3 dimer) targeting the immune checkpoints PD-L1 and CTLA-4. |
M54552 | Anselamimab | Anselamimab is a human IgG1κ anti-amyloidogenic fibrillar antibody targeting serum amyloid A1 (SAA1) for studies related to AL-type amyloidosis. |
M54551 | Rademikibart | Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases. |
M54550 | Stapokibart | Stapokibart is a humanized monoclonal antibody targeting IL-4Rα that blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit, IL-4Rα. Stapokibart is able to interact with IL-4Rα in humans, cynomolgus monkeys, and rats, and can be used in atopic dermatitis research. |
M54549 | AZD3152 | AZD3152 is a monoclonal antibody targeting SARS-CoV-2. |
M54548 | Benmelstobart | Benmelstobart is an anti-PD-L1 humanized IgG1ҡ monoclonal antibody that can be used for tumor-related studies. |
M54547 | Enlonstobart | Enlonstobart is a recombinant humanized anti-PD-1 IgG4ҡ monoclonal antibody that can be used for tumor-related studies. |
M54528 | Dargistotug | Dargistotug is a fully human IgG1 monoclonal antibody targeting T-cell immunoglobulin and the ITIM structural domain (TIGIT) that induces an immune response targeting cancer cells by blocking the TIGIT pathway. |
M54521 | Narlumosbart | Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB). |
M50212 | PRX012 | PRX012 is a potential best-in-class (BIC) anti-amyloid β (Aβ) monoclonal antibody that stimulates microglia-mediated clearance of amyloid deposits in brain tissues, and can be used in studies related to Alzheimer's disease (AD). |
M50211 | AL-002 | AL-002 is a humanized monoclonal antibody targeting myeloid triggered receptor 2 (TREM2) that improves cell survival and proliferation and increases microglia activity by activating TREM2 signaling, and can be used in studies related to Alzheimer's disease (AD). |
M50201 | BAY-3401016 | BAY-3401016 is a monoclonal antibody targeting SEMA3A for studies related to Alport syndrome. |
M50200 | BAY-3018250 | BAY-3018250 is a monoclonal antibody targeting α2-antifibrinolytic enzyme (A2AP) for use in studies related to cardiovascular disease. |
M50198 | Pelgifatamab | Pelgifatamab is a monoclonal antibody targeting prostate cancer-specific membrane antigen (PSMA) for prostate cancer-related studies. |
M50169 | IPG0521 | IPG0521 is a bifunctional antibody targeting CCR8, which can block CCR8 signaling with high intensity and weak ADCC function, and can effectively inhibit the growth of multiple tumor types in homologous and immunohumanized mouse models. |
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