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Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.
Immobilized human ROR1 at 2 ug/mL can bind zilovertamab, EC50=0.00283 ug/mL.
A549 cells were stained with zilovertamab and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.002776 ug/ml.
| CAS Number | 2485779-13-1 |
| Storage | Store at ≤ -20℃ for 24 months. Avoid repeated freeze-thaw cycles. |
[3] Anita Kumar, et al. Am Soc Clin Oncol Educ Book. New Directions for Mantle Cell Lymphoma in 2022
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| RORγ antagonist 1
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