About 30 results found for searched term "ROR" (0.047 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3931 | Aurora Kinase Inhibitor III | Aurora Kinase |
| Aurora Kinase Inhibitor 3 | ||
| Aurora Kinase Inhibitor III is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM. | ||
| M4457 | Jatrorrhizine chloride | AChR/AChE |
| Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. | ||
| M5735 | Leuprolide Acetate | LHRH/GnRH |
| Leuprorelin acetate | ||
| Leuprolide acetate is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors. | ||
| M6623 | CORM 2 | Others |
| Tricarbonyldichlororuthenium(II) dimer | ||
| CORM 2 is a carbon monoxide-releasing molecule. | ||
| M9028 | Nifuratel | Anti-infection |
| Macmiror; Magmilor; NF 113; SAP 113; Methylmercadone | ||
| Nifuratel is a local antiprotozoal and antifungal agent used in gynecology. | ||
| M9221 | GSK805 | ROR |
| ROR gamma-t-IN-1 | ||
| GSK805 is a potent, orally bioavailable RORγγ Inhibitor, with pIC50 of 8.4 and >8.2 for RORγ FRET assay and Th17 assay. | ||
| M9265 | Vimirogant | ROR |
| AGN-242428; VTP-43742; RORγ-IN-1 | ||
| Vimirogant (also known as AGN-242428 and VTP-43742) is a potent, selective and orally active RORγt inhibitor. | ||
| M10008 | Retrorsine | Alkaloids |
| Retrorsine is a naturally occurring pyrrolizidine alkaloid, which binds with DNA and inhibits the proliferative capacity of hepatocytes. | ||
| M13375 | Cetrorelix Acetate | LHRH/GnRH |
| Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Sequence：Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2 | ||
| M13781 | Dihydrorhodamine 123 | Fluorescent Dye |
| DHR 123 | ||
| Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λex=488 nm, λem=525 nm). | ||
| M14531 | Cintirorgon | ROR |
| LYC-55716 | ||
| Cintirorgon (LYC-55716) is a first-in-class, selective and orally bioavailable RORγ agonist. | ||
| M16102 | Jatrorrhizine | TNIK |
| Jatrorrhizine, an isoquinoline alkaloid found in common medicinal plants, is also a TNIK inhibitor with antibacterial, anti-inflammatory and antitumor activities. | ||
| M16690 | Dihydrorobinetin | Flavonoids |
| Dihydrorobinetin | ||
| M17098 | Dihydroresveratrol 3-O-glucoside | Phenols |
| Dihydroresveratrol 3-O-glucoside | ||
| M17196 | Dihydroresveratrol | Phenols |
| Dihydroresveratrol | ||
| M18177 | Jatrorrhizine hydrochloride | Others |
| Jatrorrhizine hydrochloride | ||
| M18311 | Tetrahydrojatrorrhizine | Antifungal |
| Tetrahydrojatrorrhizine | ||
| M18748 | Dehydrorotenone | Others |
| Dehydrorotenone | ||
| M21020 | Leuprorelin | LHRH/GnRH |
| Glp-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; Leuprolide | ||
| Leuprorelin is a natriuretic peptide analog of GnRH and a pituitary GnRH receptor agonist. It can be used in studies related to estrogen receptor (ER)-positive premenopausal breast cancer. | ||
| M22099 | Cintirorgon Sodium | Others |
| Cintirorgon Sodium | ||
| M22189 | Dextrorotation nimorazole phosphate ester | Others |
| Dextrorotation nimorazole phosphate ester | ||
| M22205 | Dextrorphan tartrate | Others |
| Dextrorphan tartrate | ||
| M22524 | Dihydrorotenone | Apoptosis |
| Dihydrorotenone is a potent mitochondrial inhibitor. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. | ||
| M25171 | Ozuriftamab | ROR |
| BA302 | ||
| Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC. | ||
| M25312 | Zilovertamab vedotin | Antibody-Drug Conjugates (ADCs) |
| VLS-101; MK-2140 | ||
| Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–drug conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer. | ||
| M25373 | Zilovertamab | ROR |
| UC-961; Cirmtuzumab | ||
| Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling. | ||
| M27931 | Cetrorelix | LHRH/GnRH |
| SB-75 | ||
| Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice. | ||
| M28137 | Cetrorelix diacetate | LHRH/GnRH |
| SB-75 diacetate | ||
| Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. | ||
| M29259 | RORγt modulator 5 | ROR |
| RORγt modulator 5 is a RORγt modulator with a Ki value of <100 nM. RORγt modulator 5 has the potential for inflammatory, metabolic, autoimmune and other diseases mediated by RORy study (WO2017132432A1; compound 2). | ||
| M29284 | Aurora kinase inhibitor-8 | Aurora Kinase |
| Aurora kinase inhibitor-8 is a highly selective inhibitor of the Aurora kinases. | ||
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