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RORγt modulator 5 

Cat. No. M29259

All AbMole products are for research use only, cannot be used for human consumption.

RORγt modulator 5  Structure

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Quality Control & Documentation
Biological Activity

RORγt modulator 5 is a RORγt modulator with a Ki value of <100 nM. RORγt modulator 5 has the potential for inflammatory, metabolic, autoimmune and other diseases mediated by RORy study (WO2017132432A1; compound 2).

Chemical Information
Molecular Weight 611.54
Formula C27H22F5N3O6S
CAS Number 2119042-65-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ji-Xuan Han, et al. Nat Microbiol. Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer

[2] Morgane M Thibaut, et al. Trends Mol Med. Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation

[3] Xinyang Song, et al. Nature. Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis

[4] Markus F Neurath. Nat Rev Gastroenterol Hepatol. Current and emerging therapeutic targets for IBD

[5] Eric V Dang, et al. Cell. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1

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  Catalog
Abmole Inhibitor Catalog




Keywords: RORγt modulator 5  supplier, ROR, inhibitors, activators

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