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CORM 2

Cat. No. M6623

All AbMole products are for research use only, cannot be used for human consumption.

CORM 2 Structure
Synonym:

Tricarbonyldichlororuthenium(II) dimer

Size Price Availability Quantity
25mg USD 50  USD50 In stock
100mg USD 150  USD150 In stock
250mg USD 300  USD300 In stock
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Biological Activity

CORM 2 is a carbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.

Chemical Information
Molecular Weight 512.01
Formula C6Cl4O6Ru2
CAS Number 22594-69-0
Solubility (25°C) DMSO 51.2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Smith, et al. Mol Pharmacol. Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes.

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Keywords: CORM 2, Tricarbonyldichlororuthenium(II) dimer supplier, inhibitors, activators

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