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Abmole Inhibitor Catalog 2017

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Inhibitors

Cat.No.  Name Information
M10671 Garcinone E Garcinone E is the most active xanthone from mangosteen, which has potent cytotoxic effect against hepatocellular carcinoma cell lines. Garcinone E might inhibit metastasis of an oral cancer cell line by blocking invasion, migration and MMP production.
M10646 GRP-60367 hydrochloride GRP-60367 hydrochloride is a first-in-class potent and selective inhibitor of rabies virus (RABV) entry that specifically targets the RABV G protein.
M10642 ML382 ML382 is a potent and selective MrgX1 (Mas-related G protein-coupled receptor X1, MRGPRX1) positive allosteric modulator with EC50 of 190 nM.
M10631 Enpp-1-IN-1 Enpp-1-IN-1, also known as MV 658, is a Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitor.
M10630 GW280264X GW280264X is an ADAM17 inhibitor.
M10613 Vitexin-4-O-glucoside Vitexin-4''-O-glucoside is a flavonoid derived from the leaves of Crataegus pinnatifida.
M10612 4-Nitroquinoline N-oxide 4-Nitroquinoline N-oxide (4-NQO) corrects DNA damage through nucleotide excision repair. 4NQO may induce DNA damage by generating reactive oxygen species thought to be produced by the enzymatic reduction of its nitro group.
M10607 NUN82647 (CU-242) NUN82647 (2-Amino-N-quinolin-8-yl-benzenesulfonamide, QBS, CU-242) is an inhibitor of cell cycle at G2 phase; it is also an apoptosis inducer.
M10583 RRX-001 RRx-001 is a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes dгυg resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity.
M10569 Bombesin Bombesin is a tetradecapeptide, which plays an important role in the release of gastrin and the activation of G-protein receptors.
M10567 Acevaltrate Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
M10566 Valepotriate (Valtrate) Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.
M10560 TNP-470 TNP-470 (AGM-1470; NSC 642492) is a synthetic analog of fumagillin (or Fumagillol) and a methionine aminopeptidase-2 inhibitor.
M10555 17α-Estradiol 17 alpha-Estradiol is a 5α-reductase inhibitor, and it inhibits testosterone metabolism catalyzed by 5 alpha-reductase.
M10554 Rebaudioside M Rebaudioside M is a natural non-calorie sweetener isolated from Stevia rebaudiana Bertoni, it is a glycoside of the ent-kaurene diterpenoid aglycone.
M10552 β-Aminopropionitrile (Liquid) β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor.
M10547 1-Phenyl-2-thiourea 1-Phenyl-2-thiourea is a useful biochemical for proteomics research.
M10544 Tentoxin Tentoxin is a cyclic tetrapeptide isolated from Alternaria tenuis, acts as a herbicide, causes seedling chlorosis, inhibits cyclic photophosphorylation and functions as an energy transfer inhibitor.
M10540 PCO371 PCO371 is a novel, orally active small molecule full agonist of PTHR1. PCO371 does not affect the PTH type 2 receptor (PTHR2).
M10539 Mitochonic acid 5 (MA-5) Mitochonic acid 5 (MA-5) reduces mitochondrial apoptosis via upregulation of mitophagy. Mitochonic acid 5 regulates mitophagy via Bnip3 through the MAPK-ERK-Yap signaling pathway.
M10535 Probenecid sodium Probenecid sodium is water-soluble, it can reduce the amount of β-lactam antibiotics in the compound, thereby effectively reducing bacterial resistance caused by ultra-high doses of antibiotics.
M10533 Chitin (BR, used for chitinase analysis) Chitin is a large, structural polysaccharide found in the cell walls of fungi, the exoskeletons of insects, and certain hard structures in fish and invertebrates.
M10529 PNPG PNPG (4-Nitrophenyl-β-D- glucopyranoside) is a chromogenic β-D-glucosidase substrate, producing a yellow solution upon cleavage.
M10527 L-Asparagine monohydrate L-Asparagine is a naturally occurring amino acid that is not an essential for humans and can be synthesized from central metabolic pathway intermediates.
M10526 L-Alanine L-Alanine (also called 2-aminopropanoic acid, α-aminopropanoic acid) is an amino acid that helps the body convert the simple glucose into energy and eliminate excess toxins from the liver.
M10525 L-Valine L-Valine is a kind of branched-chain amino acids (BCAA). Animal cannot synthesize it by itself. It must be obtained from the diet to meet their nutritional needs. Therefore L-valine belongs to the essential amino acids.
M10524 L-Tyrosine L-Tyrosine is a non-essential amino acid, is the material of a variety of body products, tyrosine is converted in vivo to a variety of biological substances by different metabolic pathways, such as dopamine, epinephrine, thyroxine, and melanin poppy (opium ) of papaverine.
M10523 L-Lysine hydrochloride L-Lysine hydrochloride
M10522 L-Histidine hydrochloride (monohydrate) L-Histidine hydrochloride
M10521 L-Cystine L-Cystine is a non-essential amino acid for human development. L-Cystine is formed by the dimerization of two cysteines through the sulfur.
M10520 FGFR1/DDR2 inhibitor 1 FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC50 values of 31.1 nM and 3.2 nM, respectively.
M10519 Furimazine Furimazine is an imidazopyrazinone substrate, it is also a Coelenterazine analogue.
M10514 Verdiperstat (AZD3241) Verdiperstat (AZD-3241) is a selective and irreversible inhibitor of myeloperoxidase (MPO) with an IC50 of 630 nM.
M10498 CCG-222740 CCG-222740 is a selective, orally active Rho/myocardin-related transcription factor (MRTF) pathway inhibitor.
M10487 NUC-7738 NUC-7738 is an effective pro-apoptotic agent in cancer cells with effects on the NF-kappaB pathway.
M10485 Oleoyl-L-α-lysophosphatidic acid sodium salt Oleoyl-L-α-lysophosphatidic acid (LPA) sodium salt is a ligand for P2Y5.
M10482 Forodesine hydrochloride Forodesine hydrochloride is a potent and orally active transition-state analog inhibitor of purine nucleoside phosphorylase, with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP.
M10479 Esaxerenone (CS-3150) Esaxerenone (CS-3150) is a highly potent and selective non-steroidal mineralocorticoid receptor antagonist.
M10464 EC5026 (BPN-19186) EC5026 (BPN-19186) is a first-in-class, potent and orally active soluble inhibitor of Epoxide Hydrolase (sEH). EC5026 has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
M10456 VPC-80051 VPC-80051 is a novel inhibitor of hnRNP A1 that targets the hnRNP A1 RBD.
M10450 D-Ribose 5-phosphate disodium D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP.
M10449 Oleic acid (Liquid) Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is also a Na+/K+ ATPase activator.
M10447 DMPC 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has the ability to enhance the constancy and in vitro antiproliferative effect of carmofur.
M10439 Evocalcet Evocalcet is a calcium-sensing receptor agonist.
M10426 1,3-Benzoxazole-6-carboxylic acid 1,3-Benzoxazole-6-carboxylic acid
M10425 Dimethyl succinate (Standard for GC) Dimethyl succinate is a biodegradable ester with low odor and low volatility and commonly serves as a flavoring agent that can be used in perfumery and personal are products, including skin-conditioning agents and emollient.
M10422 Sodium bicarbonate Sodium bicarbonate is an inorganic salt used as a buffering agent and a pH adjuster, it also serves as a neutralizer.
M10420 Proglumide Proglumide is a nonpeptide and orally active cholecystokinin (CCK)-A/B receptors antagonist.
M10419 Fmoc-Asn(Trt)-OPfp Fmoc-Asn(Trt)-OPfp is a non-essential amino acid.
M10415 Curdlan Curdlan is a polysaccharide produced by bacteria and a homopolymer of glucose with β-1,3-glucosidic linkage.


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