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Inhibitors

Cat.No.  Name Information
M2497 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
M5083 β-Cyclodextrin β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
M2189 MLN4924 MLN4924 is a novel small molecule NAE inhibitor with IC50 of 4 nM.
M8974 ALW-II-41-27 ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor with an IC50 of 11 nM for EPHA2.
M5708 Iohexol Iohexol is a contrast agent which can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo.
M13386 Myxothiazol Myxothiazol, an antifungal antibiotic, is an inhibitor of mitochondrial electron transport chain complex III (Complex III or Bc1 complex).
M13385 WGA Wheat agglutinin (WGA) is isolated from wheat (Triticum vulgaris, Weat germ), WGA selectively binds to glycoproteins and glycolipids of n-acetylglucosamine (GlcNAc) and n-acetylneuraminine (sialic acid) residues.
M13378 Antide Sequence:Ac-D2Nal-DCpa-DPal-Ser-Lys(nicotinoyl)-DLys(nicotinoyl)-Leu-Lys(isopropyl)-Pro-DAla-NH2
M13377 NE-CARBOXYMETHYL-L-LYSINE NE-CARBOXYMETHYL-L-LYSINE
M13376 Abarelix Abarelix (R3827) is the first approved antagonist for the study of GnRH in advanced prostate cancer. Sequence:Ac-{d-2-Nal}-{d-4-Cpa}-{d-3-Pal}-S-{NMyr}-{d-Asp}-L-K(ipr)-P-{d-Ala}-NH2
M13375 Cetrorelix Sequence:Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2
M13374 Ganirelix Sequence: Ac-D-2-Nal-D-Phe(4-Cl)-D-3-Pal-Ser-Tyr-D-Lys(C(NHEt)2)-Leu-Lys(C(NHEt)2)-Pro-D-Ala-NH2
M13373
M13368 IMT1B IMT1B (LDC203974) is a highly specific human mitochondrial RNA polymerase (POLRMT) inhibitor that inhibits mitochondrial DNA (mtDNA) expression. IMT1B has antitumor effects.
M13364 Tricyclazole Tricyclazole is a biosynthetic inhibitor of pentaketone melanin and a unique fungicide for rice blast control.
M13359 GSK963 GSK963 is a chiral small-molecule inhibitor of RIP1 kinase (RIPK1) with an IC50 value of 29 nM. GSK963 has strong and selective inhibitory effect on the necrosis of mouse and human cells in vitro.
M13358 GSK-843 GSK-843 is a potent ATP-competitive RIP3 (RIPK3) kinase inhibitor (IC50 = 6.5 nM) that inhibits TNF/Z-VAD-FMK/IAP agonist-induced cell necrosis in human mice (EC50 range <0.12 to 3 μM).
M13354 Angiopep-2 TFA Angiopep-2 TFA is a brain peptide carrier. Binding of the antitumor compound to angiopEP-2 peptide carrier enhances its activity in brain cancer. Amino acid serial sequence: Thr-Phe-Phe-Tyr- GLly - Glly -Ser-Arg- GLly -Lys-Arg-Asn-Asn-Phe-Lys-Thr- glu-glu-TYr
M13353 Phosphatidylcholines,soya Phosphatidylcholines, soya is a kind of extracted from soybean phosphatidyl choline, can be used for the preparation of liposomes. Has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. Phosphatidylcholines, soya can be used as animal drug delivery carrier.
M13351 DSPE-PEG(2000)-MAL DSPE-PEG-MAL is one of the reactive phospholipid PEG reagents that can react with sulfhydryl group (mercaptan, -SH). DSPE (1, 2-distearyl-Sn-glycerol 3-phosphate ethanolamine) is a highly hydrophobic saturated 18C phospholipid.
M13349 Tebipenem Tebipenem, the first oral carbapenem antibiotic, inhibits both gram-positive and gram-negative bacteria, but has no effect on Pseudomonas aeruginosa.
M13348 LyP-1 TFA Lyp-1 TFA is a circular 9-amino acid tumor-targeting peptide that selectively binds its P32 receptor protein in a variety of tumor-associated cells.
M13347 FR901464 FR901464 is an effective spliceosome inhibitor with significant antitumor and anticancer effects.
M13344 Tidiacic Tidiacic acid, a carboxylic acid derivative, can be used as pharmaceutical intermediates.
M13340 Uric acid Uric acid is a scavenger of oxygen radical, a very important antioxidant and a product of the metabolic decomposition of purine nucleotides. Helps maintain stable blood pressure and fights oxidative stress. Uric acid removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite and inhibits lipid peroxidation.



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