| Cat.No. | Name | Information |
|---|---|---|
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7791 | Exo-1 | Exo1 is a reversible inhibitor of exocytosis, also a Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator. |
| M2700 | FH1 | FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes. FH1 (NSC 12407) enhances hepatocyte functions, and promotes the differentiation of induced pluripotent stem (iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps). |
| M2560 | Y-320 | Y-320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M66393 | L-Glutamic acid potassium salt | L-Glutamic acid potassium salt can lower blood ammonia levels, plays a role in the metabolism of proteins and sugars in the brain, promotes oxidative processes, and improves central nervous system function. |
| M66383 | 2,5-Dioxopyrrolidin-1-yl acrylate | 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues. |
| M66382 | PLGA(50:50)-OH | PLGA(50:50)-OH is a hydroxyl-terminated polylactic-co-hydroxyacetic acid copolymer, suitable for research into biodegradable nanoparticles, microspheres, sustained-release implants and further surface activation and modification. The hydroxyl end groups serve as starting points for subsequent esterification, carbonate esterification, isocyanate reactions or graft modification, facilitating the construction of PLGA-PEG, PLGA-drug conjugates and multifunctional carrier precursors. |
| M66380 | Trimethyl chitosan | Trimethyl chitosan (TMC) is a derivative of Chitosan and a multifunctional polymer. Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic compounds (such as peptides and proteins) and can be used for delivery and synthesis of nanoparticles. |
| M66378 | 6-Hydroxyhexanoic acid | 6-Hydroxyhexanoic acid (6-HHA) is a biochemical reagent. It is used as a precursor to prepare surface active monomers. 6-hydroxyhexanoic acid has a role as a bacterial xenobiotic metabolite. |
| M66377 | L-Tyrosine, N-(2-chloroacetyl)-, cyanomethyl ester | L-Tyrosine, N-(2-chloroacetyl)-, cyanomethyl ester is an amino acid derivative, commonly used as an intermediate in organic synthesis or as a starting material for peptide synthesis. |
| M66369 | PEG5000-SVA | PEG5000-SVA is a polyethylene glycol derivative bearing SVA functional groups, suitable for applications such as protein and peptide modification, drug delivery systems, biosensing and labelling, and surface modification of materials. |
| M66368 | Polysucrose T-70 | Polysucrose T-70 (same as Ficoll PM 70) is a water-soluble polysaccharide polymer formed by the cross-linking of sucrose with epichlorohydrin. It is widely used in the fields of biomedicine and life sciences, including cell separation, density gradient centrifugation, drug delivery, in vivo tracing and biosensing. |
| M66367 | DSPE-PEG2000-T7 | DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists. |
| M66357 | 1,3,6,8-Tetrakis[p-benzoic acid]pyrene | 1,3,6,8-Tetrakis[p-benzoic acid]pyrene (4,4',4'',4'''-(Pyrene-1,3,6,8-tetrayl)tetrabenzoic acid) is a metal-organic framework (MOF). |
| M66342 | Thionicotinamide | Thionicotinamide (TN), an NAD+ analog, is converted to NADPS upon cell entry and also exhibits cytotoxicity in various cancer cell lines due to NADK inhibition. Thionicotinamide upregulates ROS in C85 cells through downregulation of NADPH. Thionicotinamide also inhibits fatty acid synthesis and nucleotide synthesis pathways, both of which are NADPH-dependent. |
| M66328 | β-D-Fructose | β-D-Fructose is a monosaccharide. Derivatives synthesized using β-D-Fructose as the sugar backbone exhibit potent and selective antiproliferative activity against breast cancer MCF-7 cells. |
| M66323 | Deferoxamine-DBCO | Deferoxamine-DBCO is a bifunctional chelating agent. Deferoxamine-DBCO efficiently chelates with radioactive metals (such as 89Zr) through the DFO structure to achieve radiolabeling. Deferoxamine-DBCO undergoes a metal-free Huisgen cycloaddition reaction with azide-containing biomolecules (such as siRNA, monoclonal antibodies) under bioorthogonal conditions through the DBCO structure to achieve targeted coupling. |
| M66308 | HS-PEG-PBA (MW 2000) | HS-PEG-PBA (MW 2000) is a functional polyethylene glycol derivative that utilises the interaction between phenylboronic acid and sugar molecules to enable targeted recognition of sugar receptors. HS-PEG-PBA forms reversible bonds with sugar molecules and serves as a core material for biosensors, enabling the highly sensitive detection of specific biomolecules. It is widely used in fields such as biomaterial modification, molecular recognition and drug delivery. |
| M66287 | AA92593 | AA92593 is a selective and competitive melanopsin OPN4 antagonist, its presence in the retinal-binding pocket of melanopsin leads to the displacement of retinal, which could trigger a downstream signaling that would ultimately result in Per1 increased expression. |
| M66280 | 8-Arm PEG-VS (20K) | 8-Arm PEG-Vinylsulfone is a versatile PEG reagent featuring eight thiol-reactive vinylsulfone groups. VS reacts selectively with free thiols (SH groups) to enable site-specific PEGylation of peptides and proteins. Due to its eight-arm star structure and high functional group density, 8-Arm PEG-VS enables rapid and stable conjugation as well as multi-ligand co-modification (e.g. targeting ligands + drugs), making it suitable for drug delivery and high-strength hydrogels. |
| M66279 | Chondroitin Sulfate Methacryloyl | Chondroitin Sulphate Methacryloyl (ChS-MA) is a modified form of chondroitin sulphate that can be cross-linked and cured into a gel under the action of a photoinitiator using ultraviolet and visible light. It has been widely applied in numerous biomedical research fields, including the treatment of osteoarthritis, the repair of articular cartilage, and cranial bone repair. It can be used to construct a variety of biomaterials, such as nanocarriers for the diagnosis and treatment of tumours, as well as bioadhesives. Application: cell culture, biological 3D printing, tissue engineering, etc. |
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