All AbMole products are for research use only, cannot be used for human consumption.
Exo1 is a reversible inhibitor of exocytosis, also a Golgi ARF 1 (ADP-Ribosylation Factor) GTPase activator. Exo1 inhibits exocytosis with an IC50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.
J Control Release. 2022 Dec 15;353:675-684.
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia
Exo-1 purchased from AbMole
| Molecular Weight | 273.26 |
| Formula | C15H12NFO3 |
| CAS Number | 75541-83-2 |
| Solubility (25°C) | DMSO 24 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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