Free shipping on all orders over $ 500

Vimirogant

Cat. No. M9265

All AbMole products are for research use only, cannot be used for human consumption.

Vimirogant Structure
Synonym:

AGN-242428; VTP-43742; RORγ-IN-1

Size Price Availability
1mg USD 800  USD800 Custom Synthesis
5mg USD 2700  USD2700 Custom Synthesis
Free Delivery on orders over USD 500 Bulk Inquiry?
Quality Control & Documentation
Biological Activity

Vimirogant is a RORγ inhibitor, which has a Ki value of <100 nM. Vimirogant is used for the research of treating autoimmune disorders, including multiple sclerosis and psoriasis.

Chemical Information
Molecular Weight 552.65
Formula C27H35F3N4O3S
CAS Number 1802706-04-2
Solubility (25°C) DMSO 10 mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pandya VB, et al. J Med Chem. Combating Autoimmune Diseases With Retinoic Acid Receptor-Related Orphan Receptor-γ (RORγ or RORc) Inhibitors: Hits and Misses.

[2] Gege C, et al. Expert Opin Ther Pat. RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345.

[3] Gege C. Expert Opin Ther Pat. Retinoid-related orphan receptor gamma t (RORγt) inhibitors from Vitae Pharmaceuticals (WO2015116904) and structure proposal for their Phase I candidate VTP-43742.

Related ROR Products
ASN06917370 

ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases.
JTE-151

JTE-151 is a RORγ inhibitor that suppresses overactive immune responses by inhibiting RORγ associated with Th17 cell activation.JTE-151 can be used in studies related to autoimmune diseases.
SAR-441169

SAR-441169 is a RORγt inverse agonist that can be used in studies related to psoriasis.
GRC-39815

GRC-39815 is a RORγt inverse agonist that can be used in studies related to chronic obstructive pulmonary disease.
RORγ antagonist 1

RORγ antagonist 1, a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM).
  Catalog
Abmole Inhibitor Catalog




Keywords: Vimirogant, AGN-242428; VTP-43742; RORγ-IN-1 supplier, ROR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.