All AbMole products are for research use only, cannot be used for human consumption.
Afimkibart (PF-06480605) is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC).
| CAS Number | 2911580-96-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TNF Receptor Products |
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| Atrosab
Atrosab is a humanized IgG1 antagonistic anti-TNFR1 antibody. Atrosab inhibits TNF-mediated Apoptosis induction and IL-6 and IL-8 production. Atrosab reduces neurological deficits. |
| Mesaconitine
Mesaconitine is the main active ingredient of Aconitum and has many pharmaceutical effects. |
| Hypaconitine
Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism. |
| Shikonin
Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844) is an effective and specific inhibitor of Pyruvate kinase M2 (PKM2). Shikonin is the main ingredient of Lithosia, a Chinese herb with a variety of biological activities. Shikonin acts as an anti-inflammatory by inhibiting tumor necrosis factor-α (TNF-α), Proteasome can inhibit the activation of nuclear factor-κB (NF-κB) signaling pathway. |
| Forsythoside B
Forsythoside B inhibits TNF-alpha, IL-6, IκB and modulate NF-κB. |
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