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Etanercept

Cat. No. M6224

All AbMole products are for research use only, cannot be used for human consumption.

Etanercept Structure
Size Price Availability Quantity
2mg USD 580  USD580 In stock
5mg USD 780  USD780 In stock
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Quality Control & Documentation
Biological Activity

Etanercept is a dimer fusion protein that binds tumor necrosis factor (TNF) as a TNF inhibitor. Etanercept competitively inhibits the binding of TNF-α and TNF-β to TNF receptors on the cell surface, rendering tumor necrosis factor biologically inactive.

Product Citations
Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models CIA rats
Formulation
Dosages 5 mg/kg
Administration s.c.
Chemical Information
Molecular Weight 51234.33
Formula C2224H3475N621O698S36
CAS Number 185243-69-0
Storage -80°C for long term
References

[1] Hong Xue, et al. Int J Chron Obstruct Pulmon Dis . Etanercept Protected Against Cigarette Smoke Extract-Induced Inflammation and Apoptosis of Human Pulmonary Artery Endothelial Cells via Regulating TNFR1

[2] Ya Li, et al. Molecules . M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction

[3] Chen X, et al. Drug Metab Dispos. Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats

[4] Murdaca G, et al. Expert Opin Drug Saf. Efficacy and safety of etanercept in chronic immune-mediated disease.

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Keywords: Etanercept supplier, Fusion Proteins, inhibitors, activators

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