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Evorpacept (ALX148) is a high affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region designed to enhance the activity of other anti-neoplastic therapies, with minimal additional toxicity.
Evorpacept (ALX148) is a CD47-blocking myeloid checkpoint inhibitor. The myeloid checkpoint inhibitor evorpacept was well tolerated in combination with azacitidine (AZA) with an initial safety profile similar to that of AZA monotherapy.
| CAS Number | 2484949-51-9 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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