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Atacicept

Cat. No. M25255

All AbMole products are for research use only, cannot be used for human consumption.

Atacicept Structure
Synonym:

TACI-Ig; TACI-Fc 5

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Quality Control & Documentation
Biological Activity

Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease.

Chemical Information
CAS Number 845264-92-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Mahya Eslami, et al. Front Immunol. Kinetics of free and ligand-bound atacicept in human serum

[2] Joan T Merrill, et al. Arthritis Rheumatol. Efficacy and Safety of Atacicept in Patients With Systemic Lupus Erythematosus: Results of a Twenty-Four-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm, Phase IIb Study

[3] Christophe Richez, et al. Expert Opin Investig Drugs. Atacicept as an investigated therapy for rheumatoid arthritis

[4] H-P Hartung. Nervenarzt. [Atacicept: a new B lymphocyte-targeted therapy for multiple sclerosis]

[5] C Bracewell, et al. Expert Opin Biol Ther. Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis

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Keywords: Atacicept, TACI-Ig; TACI-Fc 5 supplier, inhibitors, activators

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