All AbMole products are for research use only, cannot be used for human consumption.
Bevacizumab is A humanized IgG1 monoclonal antibody that binds with high affinity and specificity to all VEGF-A.
Talanta. 2025 Apr 1;285:127431.
Biologically-driven RAFT polymerization-amplified platform for electrochemical detection of antibody drugs
Bevacizumab purchased from AbMole
Anal Chem. 2024 Jun 4;96(22):9278-9284.
Site-Directed Electrochemical Grafting for Amplified Detection of Antibody Pharmaceuticals
Bevacizumab purchased from AbMole
Anal Chem. 2023 Sep 19;95(37):14094-14100.
Amplification-Free Ratiometric Electrochemical Aptasensor for Point-of-Care Detection of Therapeutic Monoclonal Antibodies
Bevacizumab purchased from AbMole
EMBO Mol Med. 2022 May 9;14(5):e14844.
SARS‐CoV‐2 spike spurs intestinal inflammation via VEGF production in enterocytes
Bevacizumab purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | NSCLC cell lines |
| Preparation method | Six NSCLC cell lines were seeded (~2,000–5,000 cells per well, depending on cell type) onto 96-well plates. After 24 h of incubation, cells were treated with erlotinib (0–20 µmol/L), bevacizumab (0–20 ng/mL) or a combination of these agents (erlotinib 1 µmol/L; bevacizumab 10 ng/mL) for 72 h in serum-containing medium. The viability was determined by MTS assay (Promega, Madison, WI) according to the manufacturer’s instructions. |
| Concentrations | 0–20 ng/mL |
| Incubation time | 72 h |
| Animal Experiment | |
|---|---|
| Animal models | Female Wistar rats |
| Formulation | 0.9%sodium chloride solution |
| Dosages | 30 mg/kg |
| Administration | i.p. |
| CAS Number | 216974-75-3 |
| Solubility (25°C) | Water PBS |
| Storage | Store at -20°C or -70°C. Avoid multiple freeze-thaws. |
[1] Liu W, et al. Eye Sci. Effect of Avastin on the migration and invasion of pterygium fibroblasts.
| Related VEGFR/PDGFR Products |
|---|
| Conbercept
Conbercept (KH902) is a monoclonal antibody targeting VEGFRA fused to the IGHG1 Fc fragment. Conbercept is produced by the fusion of the second C-LIKE of FLT1 and the third and fourth C-LIKE of KDR with IGHG1 Fc. |
| SU5208
SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2). |
| VEGFR-IN-1
VEGFR-IN-1 is a potent angiogenesis inhibitor with IC50s of 0.02, 0.18, 0.24 7.3, and 7 µM for KDR, Flt-1, c-Kit, EGF-R, and c-Src, respectively. |
| (Z)-Orantinib
(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 0.008, and 1.2 µM, respectively. |
| (Rac)-SAR131675
(Rac)-SAR131675 is the racemate of SAR131675. |
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