Cat.No. | Name | Information |
---|---|---|
M9370 | Recombinant Human TNF α (HEK293, C-His) | Recombinant Human TNF α (HEK293, C-His) plays an important role in growth regulation, differentiation, inflammatory response, viral replication, tumorigenesis, autoimmune diseases, and viral, bacterial, fungal, and parasitic infections. |
M9413 | Recombinant Human VEGF165 Protein (HEK293, C-His) | Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine, it promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. |
M10922 | Recombinant Mouse TGF-beta 1 Protein (Human Cells) | Recombinant Mouse TGF-beta 1 Protein is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis. ED50 is 5-25 pg/ml |
M9391 | Recombinant Human TGF-β1 (HEK293, C-Fc) | Recombinant Human TGF-β1 (HEK293) regulates cell proliferation, growth, differentiation and cells movement. The ED50 is ≤ 0.5 ng/mL as measured by HT-2 cells. |
M9241 | Recombinant Human EPO Protein (HEK293, C-His) | Erythropoietin (EPO) is a glycoprotein hormone known primarily for its role in erythropoiesis, which is responsible for stimulating the proliferation and differentiation of erythroid progenitor cells. |
M9402 | Recombinant Human PDGF-BB Protein (HEK293, C-His) | Recombinant Human PDGF-BB Protein (HEK293) |
M9987 | Recombinant Human PDGF-AA Protein (HEK293) | Recombinant Human PDGF-AA Protein (HEK293) is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. |
M9981 | Recombinant Human IL-11 Protein (HEK293) | Recombinant Human IL-11 Protein (HEK293) is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. |
M21094 | Recombinant Rat IL-1β (E. coli) | Interleukin-1β (IL-1β) is a non-secreted pro-inflammatory cytokine produced primarily by activated macrophages as well as neutrophils, epithelial cells and endothelial cells. Measured by a cell proliferation assay using mouse D10S cells, the ED50 is < 10.0 pg/ml, corresponding to a specific activity of > 1.0 × 108 units/mg. |
M10022 | Recombinant Mouse GM-CSF Protein (CHO) | Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory stimuli. ED50 < 0.05 ng/ml, measured in a cell proliferation assay using mouse FDC-P1 cells, corresponding to a specific activity of > 2.0 × 107 units/mg. |
M45052 | Recombinant Human IL-7 (Mammalian, C-6His) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. |
M45051 | Recombinant Human IL-7 (E. coli) | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. |
M43971 | Recombinant Human MMP12 Protein (E. coli) | Matrix metalloproteinase-12 (MMP12) is a macrophage-secreted elastase that is highly induced in the liver and lung in response to S. mansoni eggs and contains four hemopexin-like domains. MMP12 is a proteolytic enzyme responsible for the cleavage of plasminogen to angiotensin, which has an angiostatic effect. |
M43970 | Recombinant Human MMP-8 Protein (HEK293, C-His) | Matrix metalloproteinase-8 (MMP-8) is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in dгυg development. |
M43969 | Recombinant Mouse MMP-12 (Mammalian, C-6His) | Matrix metalloproteinase-12 (MMP12) contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. |
M43966 | Recombinant Human IL-1β Protein (E.coli) | Interleukin 1 beta (IL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. |
M43961 | Recombinant Human Claudin-6/CLDN6 Full Length Protein (HEK293, VLP) | Claudin-6 (CLDN6) belongs to the claudins family. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. |
M43960 | Recombinant Mouse Sclerostin (Mammalian, C-6His) | Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation. |
M43959 | Recombinant Human Sclerostin (Mammalian, C-6His) | Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST has anti-anabolic effects on bone formation. |
M43958 | Recombinant Rat SDF-1/CXCL12 (E. coli) | SDF-1 also known as CXCL12 is belonging to the CXC chemokine family. SDF-1 binds primarily to CXC receptor 4 (CXCR4; CD184). The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription. |
M43957 | Recombinant Human TNF RII (Mammalian, C-6His) | Recombinant Human TNF RII belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). |
M43949 | Recombinant Rat HGF Protein (HEK293) | Hepatocyte growth factor, also known as HGF, belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. |
M43941 | Recombinant Human TPA Protein (Mammalian, C-6His) | Tissue-type plasminogen activator (TPA) is a protein that secreted into extracellular space. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, TPA plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-translational activation of growth factors. |
M43923 | Recombinant Human Dectin-1 Protein (Mammalian, N-Fc) | Dectin-1 is the most important receptor for beta-glucan. It is a type II transmembrane protein which binds beta-1,3 and beta-1,6 glucans, and is expressed on most cells of the innate immune system and has been implicated in phagocytosis as well as killing of fungi by macrophages, neutrophils and dendritic cells. |
M43922 | Recombinant Mouse Dectin-1 Protein (HEK293, His Tag) | Dectin-1 is the most important receptor for beta-glucan. Dectin-1 can recognize and respond to live fungal pathogens and is being increasingly appreciated as having a key role in the innate responses to these pathogens. |
M43920 | Recombinant Human Catalase/CAT (E.coli) | Catalase (CAT) is a member of the catalase family. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. |
M43918 | Recombinant Human Calreticulin Protein (HEK293, C-His) | Calreticulin acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. |
M43917 | Recombinant Human Thrombospondin-1 Protein (E. coli, N-His) | Thrombospondin-1 (THBS1; TSP1) regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and antithrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells(EC), and destabilizes adhesive contacts between EC. |
M43869 | Recombinant Human Integrin alpha V beta 3 Protein (HEK293, C-His) | Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. |
M43836 | Recombinant Human AP2 Gamma/TFAP2C Protein (E. coli, His Tag) | TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. TFAP2C may be prognostic indicators for breast tumors. |
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