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Recombinant Human VEGF165(HEK293)

Cat. No. M9413
Recombinant Human VEGF165(HEK293) Structure
Size Price Availability Quantity
10ug USD 188  USD188 In stock
20ug USD 280  USD280 In stock
50ug USD 540  USD540 In stock
100ug USD 880  USD880 In stock
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Quality Control & Documentation
  • Purity: ≥95%, Endotoxin ≤0.01EU/ug
  • COA
  • MSDS
Biological Activity

Recombinant Human VEGF165(HEK293) is a powerful growth and angiogenic cytokine. It promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays an important role in normal and pathological angiogenesis.

Product Citations
Chemical Information
Solubility (25°C) Water
Saline
PBS
Storage 2-8°C, dry, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Robin M H Rumney, et al. Sci Rep. In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis

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