All AbMole products are for research use only, cannot be used for human consumption.
The role of Recombinant Human IL-4 Protein (CHO) in the induction of monocytes into DCs is to inhibit the overgrowth of macrophages, thereby directing monocyte differentiation toward DCs. Also, IL-4 has the ability to reduce cell surface expression of CD14 molecules, an important marker for the differentiation of monocytes into DCs. The combined effect of GM-CSF and IL-4 can lead to targeted differentiation of monocytes into immature DCs, which have a strong capacity for antigen uptake and processing, but a weak capacity for antigen presentation.
DNA sequence encoding human IL-4 ( GenBank: AAH70123.1 H25-S153 ) expressed with an Fc tag at the C- terminus.
Measured by the cell proliferation assay with TF-1 cells, the ED50 is ≤0.5 ng/mL.
Endotoxin <0.1 EU/μg
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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