All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human TGF-β1 regulates cell proliferation, growth, differentiation and cells movement. TGFβ is released from degranulating platelets and secreted by all of the major cell types participating in the repair process, including lymphocytes, macrophages, endothelial cells, smooth muscle cells, epithelial cells, and fibroblasts. Mammals express three isoforms of TGFβ designated TGFβI, TGFβ2, and TGFβ3; TGFβ1 is the most abundant isoform in all tissues, and in human platelets it is the only isoform of the peptide. TGFβ1 has immunomodulatory effects. TGFβ1 has profibrogenic effects.
Measured in ability to inhibit the mouse IL-4-dependent proliferation of HT-2 cells, the ED50 is < 0.2 ng/ml.
DNA sequence encoding human TGF-β1 (Ala279-Ser390) expressed.
Apparent Molecular Weight: 12~13 KDa, reducing conditions
Endotoxin: <0.1EU/μg
Toxicol Appl Pharmacol. 2024 Jun 27.
Serum deprivation protein response intervenes in the proliferation, motility, and extracellular matrix production in keloid fibroblasts by blocking the amplification of TGF-β1/SMAD signal cascade via ERK1/2
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Eur J Med Res. 2024 Dec 28;29(1):631.
MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway
Recombinant Human TGF-β1 (CHO) purchased from AbMole
Allergol Immunopathol (Madr). 2022 Mar 1;50(2):104-114.
6-Gingerol, a functional polyphenol of ginger, reduces pulmonary fibrosis by activating Sirtuin1
Recombinant Human TGF-β1 (CHO) purchased from AbMole
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Source | Recombinant Human TGF-β1 (AbMole) |
| Method | SDS-PAGE analyses | |
| Cell Lines | ||
| Concentrations | ||
| Incubation Time | ||
| Results | The purity is > 97 % by SDS-PAGE analyses. |
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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