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Recombinant Mouse TGF-beta 1 Protein (Human Cells)

Cat. No. M10922

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse TGF-beta 1 Protein (Human Cells) Structure
Synonym:

TGF-β1, Mouse

Size Price Availability Quantity
5ug USD 180  USD180 In stock
10ug USD 280  USD280 In stock
50ug USD 800  USD800 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
Biological Activity

TGF-beta 1 protein, Mouse is a multifunctional cytokine that controls many biological processes including immunity, differentiation, tumor suppression, tumor metastasis, aging, migration, wound healing, apoptosis, cell division, adipogenesis, and osteogenesis.

ED50 is 5-25 pg/ml, measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells.


Accession # P04202

Apparent Molecular Weight: ~12.8 kDa, reducing conditions

Endotoxin < 1 EU/μg

Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.

Product Citations
Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O up to 100 μg/ml
Storage Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
References

[1] Yen-Ting Chen, et al. J Clin Invest. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts

[2] Kevin K Kim, et al. Cold Spring Harb Perspect Biol. TGF-β1 Signaling and Tissue Fibrosis

[3] Xiaomeng Wang, et al. Nature. LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling

[4] Daisuke Sugiyama, et al. Mech Dev. TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts

[5] Li Xiao, et al. Front Biosci (Landmark Ed). TGF-beta 1 induced fibroblast proliferation is mediated by the FGF-2/ERK pathway

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Keywords: Recombinant Mouse TGF-beta 1 Protein (Human Cells), TGF-β1, Mouse supplier, Recombinant Proteins, inhibitors, activators

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