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Recombinant Human FGF-basic (145aa, E. coli) also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.
Measured by the cell proliferation assay using 3T3 cells, the ED50 is < 0.25 ng/ml, corresponding to a specific activity of > 4.0 × 106 units/mg.
Accession: P09038
Apparent Molecular Weight: ~16.4 kDa, reducing conditions.
Lyophilized after extensive dialysis against PBS.
Adv Biotechnol (Singap). 2025 Mar 11; .
Simplifying the protocol for low-pollution-risk, efficient mouse myoblast isolation and differentiation
Recombinant Human FGF-basic (145aa, E. coli) purchased from AbMole
Patent. CN119144548A 2024 Dec 17.
Patent. CN119144548A
Recombinant Human FGF-basic (145aa, E. coli) purchased from AbMole
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
[5] D Ledoux, et al. Prog Growth Factor Res. Interactions of FGFs with target cells
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Products are for research use only. Not for human use. We do not sell to patients.
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