All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human FGF-basic (145aa, E. coli) also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.
Measured by the cell proliferation assay using 3T3 cells, the ED50 is < 0.25 ng/ml, corresponding to a specific activity of > 4.0 × 106 units/mg.
Accession: P09038
Apparent Molecular Weight: ~16.4 kDa, reducing conditions.
Lyophilized after extensive dialysis against PBS.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml |
| Storage | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
[5] D Ledoux, et al. Prog Growth Factor Res. Interactions of FGFs with target cells
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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