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EDTA disodium

Cat. No. M9878
EDTA disodium Structure
Size Price Availability Quantity
10g USD 20  USD20 In stock
50g USD 40  USD40 In stock
100g USD 55  USD55 In stock
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Quality Control
  • Current batch:
  • Purity >98.5%, AR
  • COA
  • MSDS
Biological Activity

EDTA disodium is a chelating agent; sequesters di- and trivalent metal ions.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 372.23
Formula C10H14N2Na2O8.2(H2O)
CAS Number 6381-92-6
Purity >98.5%, AR
Solubility Water 50 mg/mL
Storage 2-8°C, dry, sealed
References

[1] S J Hepziba Magie Jessima, et al. Corrosion mitigation performance of disodium EDTA functionalized chitosan biomacromolecule - Experimental and theoretical approach

[2] Alessandro Fulgenzi, et al. EDTA Chelation Therapy for the Treatment of Neurotoxicity

[3] Virginia M Weaver, et al. Does calcium disodium EDTA slow CKD progression?

[4] Rebecca S Lanigan, et al. Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: EDTA disodium supplier, inhibitors

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