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IR808 (MHI-148) is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. IR808 (MHI-148) is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells. IR808, which acts as an optical imaging agent, targeting moiety and also trigger on-demand drug release on application of NIR 808 nm laser.
Emission 808 nm
Excitation 782 nm
Bioactive Materials. 2025 May 21; .
NIR-responsive bio-system with sequential antibacterial and immunomodulatory effects for the treatment of periodontitis
IR808 purchased from AbMole
Aggregate. 2024 Dec 19.
Fluorescent Nanoparticles Achieve Efficient Photothermal Conversion and Enhanced Antitumor Efficacy Through Intermolecular Aggregation-Caused Quenching
IR808 purchased from AbMole
Drug Deliv. 2021 Dec;28(1):2256-2267.
GLUT1 targeting and hypoxia-activating polymer-drug conjugate-based micelle for tumor chemo-thermal therapy
IR808 purchased from AbMole
| Molecular Weight | 764.24 |
| Formula | C42H52BrClN2O4 |
| CAS Number | 172971-76-5 |
| Solubility (25°C) | DMSO 10 mg/mL |
| Storage | -20°C, protect from light |
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