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Cat. No. M11151
IR808 Structure

MHI-148; IR 808

Size Price Availability Quantity
5mg USD 40  USD40 In stock
10mg USD 60  USD60 In stock
25mg USD 100  USD100 In stock
50mg USD 160  USD160 In stock
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Quality Control & Documentation
Biological Activity

IR808 (MHI-148) is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. IR808 (MHI-148) is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells. IR808, which acts as an optical imaging agent, targeting moiety and also trigger on-demand drug release on application of NIR 808 nm laser.

Emission  808 nm

Excitation 782 nm

Product Citations
Chemical Information
Molecular Weight 764.24
Formula C42H52BrClN2O4
CAS Number 172971-76-5
Solubility (25°C) DMSO 10 mg/mL
Storage -20°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Pengkai Ma, et al. Drug Deliv. GLUT1 targeting and hypoxia-activating polymer-drug conjugate-based micelle for tumor chemo-thermal therapy

[2] Peipei Jia, et al. J Mater Chem B. Integration of IR-808 and thiol-capped Au-Bi bimetallic nanoparticles for NIR light mediated photothermal/photodynamic therapy and imaging

[3] Sujun Wang, et al. J Biomed Mater Res A. Study on the optical and biological properties in vitro of IR808-PEG-FA

[4] Miguel M Leito, et al. Adv Healthc Mater. Prototypic Heptamethine Cyanine Incorporating Nanomaterials for Cancer Phototheragnostic

[5] Lihua Zhou, et al. Small. Dye-Anchored MnO Nanoparticles Targeting Tumor and Inducing Enhanced Phototherapy Effect via Mitochondria-Mediated Pathway

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Keywords: IR808, MHI-148; IR 808 supplier, Fluorescent Dye, inhibitors, activators

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