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Cat. No. M10457
PEG400 Structure

PEG-400; Polyethylene glycol

Size Price Availability Quantity
100mL USD 50  USD50 In stock
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Quality Control
  • Current batch:
  • Purity average Mn 400
  • COA
  • MSDS
Biological Activity

PEG400 is a neutral and biocompatible hydrophilic polymer. PEG-400 is usually used to modify therapeutic proteins and peptides to increase their solubility.

Product Citations
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 44.05
Formula HO(CH2CH2O)nH
CAS Number 25322-68-3
Purity average Mn 400
Solubility DMSO ≥ 60 mg/mL
Water ≥ 45 mg/mL
Storage 2-8°C, dry, sealed
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Keywords: PEG400, PEG-400; Polyethylene glycol supplier, Solvent & Hydrotropic Agents, inhibitors

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