PEG400 is a neutral and biocompatible hydrophilic polymer. PEG-400 is usually used to modify therapeutic proteins and peptides to increase their solubility.
Cancers (Basel). 2021 May 12;13(10):2310.
Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA
PEG400 purchased from AbMole
|Solubility (25°C)||DMSO ≥ 60 mg/mL
Water ≥ 45 mg/mL
|Storage||2-8°C, dry, sealed|
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 Siyuan Cao, et al. Pharmacol Res Perspect. The pharmaceutical excipient PEG400 affect the absorption of baicalein in Caco-2 monolayer model by interacting with UDP-glucuronosyltransferases and efflux transport proteins
|Related Solvents & Excipients Products|
|PLGA lactide:glycolide (50:50) (MW 90000)
PLGA lactide:glycolide (50:50) (MW 90000) Poly(D,L-propylidene-CO-ethylidene glycolide) is a synthetic amino acid that can be used for macromolecular delivery.
Soluplus is an amphiphilic polymer that enhances the solubility and bioavailability of difficult-to-solve substances and can be used in studies related to drug delivery.
Polyvinyl alcohol (PVA) is a versatile water-soluble polymer that can be used in studies related to drug delivery.
PEG200 is a neutral and biocompatible hydrophilic polymer.
Polyethylene glycol 20000 (PEG 20000) is a polymer formed by condensation reaction of ethylene oxide and water. Polyethylene glycol is used for the isolation of plasmid DNA and the precipitation of phage.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.