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Recombinant Human TNF α(HEK293)

Cat. No. M9370
Recombinant Human TNF α(HEK293) Structure
Synonym:

TNFSF2(HEK293)

Size Price Availability Quantity
10ug USD 128  USD160 In stock
20ug USD 192  USD240 In stock
100ug USD 320  USD400 In stock
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Quality Control
  • Current batch:
  • Purity >95%, Potency >1×107IU/mg
  • COA
  • MSDS
Biological Activity

Recombinant Human TNF α

Endotoxin <0.01EU/ug

Product Citations
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number
Purity >95%, Potency >1×107IU/mg
Solubility Water
Saline
PBS
Storage 2-8°C, dry, protect from light, sealed
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