2-NBDG is a fluorescent glucose analog for visualizing glucose uptake into living cells.
Arch Pharm Res. 2024 Feb;47(2):127-145.
Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways
2-NBDG purchased from AbMole
J Diabetes. 2023 Aug 18.
Decreased in n-3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction
2-NBDG purchased from AbMole
Nano Today. 2022 August;101541.
Dual regulation on oxidative stress and endoplasmic reticulum stress by [70] fullerenes for reversing insulin resistance in diabetes
2-NBDG purchased from AbMole
Biofabrication. 2022 May 26;4(3).
Dual-core coaxial bioprinting of double-channel constructs with a potential for perfusion and interaction of cells
2-NBDG purchased from AbMole
Proteomics Clin Appl. 2022 Jan;16(1):e2100031.
Quantitative proteomics analysis reveals novel insights into mechanisms of action of disulfiram (DSF)
2-NBDG purchased from AbMole
Front Immunol. 2021 Aug 26;12:728082.
Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation
2-NBDG purchased from AbMole
| Molecular Weight | 342.26 |
| Formula | C12H14N4O8 |
| CAS Number | 186689-07-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 14 mg/mL |
| Storage | -20°C, protect from light |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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