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2-NBDG

Cat. No. M6327
2-NBDG Structure
Size Price Availability Quantity
1mg USD 80 In stock
5mg USD 250 In stock
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Quality Control
Biological Activity

2-NBDG is a fluorescent glucose analog for visualizing glucose uptake into living cells.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 342.26
Formula C12H14N4O8
CAS Number 186689-07-6
Purity >98%
Solubility DMSO 14 mg/mL
Storage at -20°C
References

2-NBDG as a Fluorescent Indicator for Direct Glucose Uptake Measurement
Chenhui Zou, et al. J Biochem Biophys Methods. 2005 Sep 30;64(3):207-15. PMID: 16182371.

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  Catalog
Abmole Inhibitor Catalog 2017




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