4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene (BODIPY 493/503) is a lipophilic fluorescent probe that localizes to polar lipids and can be used to label cellular neutral lipid contents, particularly those localized to lipid droplets, in live and fixed cells. It displays excitation/emission maxima of 493/503 nm, respectively.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Storage||-20°C, protect from light, dry, sealed|
Age-related ultrastructural changes of the basement membrane in the mouse blood-brain barrier
Laura Cristina Ceafalan, et al. J Cell Mol Med. 2019 Feb;23(2):819-827. PMID: 30450815.
BODIPY 493/503 Staining of Neutral Lipid Droplets for Microscopy and Quantification by Flow Cytometry
Bo Qiu, et al. Bio Protoc. 2016 Sep 5;6(17):e1912. PMID: 28573161.
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